| Smickeonn - The Game Deluxe | 2024 | gbc |
| The Smurfs | 1994 | gb, genesis, nes |
| The Smurfs | 1994 | gg, sms, snes |
| The Smurfs | 1999 | ps1 |
| The Smurfs | 1994 | segacd |
| The Smurfs Nightmare | 1997 | gb, gbc |
| The Smurfs Travel the World | 1995 | gb, snes |
| Snail Against Squirrel | 1983 | a2600 |
| Snailo! | 2025 | nes |
| Snake Pass | 2017 | ps4, switch, xboxone |
| Snake Rattle n Roll | 1990 | genesis, nes |
| Snap Jack | 1981 | arcade |
| Sneaky Snakes | 1991 | gb |
| Snoopy's Grand Adventure | 2015 | 3ds, ps4, wiiu, xbox360, xboxone |
| Snow Bros. - Nick & Tom | 1990 | arcade, gb, genesis, nes |
| Snow Bros. 2 - With New Elves / Otenki Paradise | 1994 | arcade |
| Snow Brothers 3 - Magical Adventure | 2002 | arcade |
| Snow White and the Seven Dwarfs | 2001 | gbc |
| Snow White in Happily Ever After | 1994 | snes |
| So Many Me | 2017 | ps4 |
| Soccer Kid | 1993 | 3do, cd32, snes |
| Soccer Kid | 2002 | gba, ps1 |
| Soccer Kid | 2000 | jaguar |
| Sofia the Witch - Curse of the Monster Moon | 2023 | gbc |
| Sokonuke Taisen Game | 1995 | arcade |
| Solar-Warrior | 1986 | arcade |
| Somari | 1994 | nes |
| Son Son | 1986 | nes |
| Son Son | | wii |
| SonSon | 2010 | wii |
| Song of Nunu: A League of Legends Story | 2023 | switch |
| Songbird Symphony | 2019 | ps4 |
| Sonic & Knuckles | 1994 | genesis, wii, xbox360 |
| Sonic & Knuckles + Sonic 3 | 1994 | genesis |
| Sonic & Knuckles + Sonic The Hedgehog | 1994 | genesis |
| Sonic & Knuckles + Sonic The Hedgehog 2 | 1994 | genesis |
| Sonic & Knuckles + Sonic The Hedgehog 2 + Sonic The Hedgehog 3 | | genesis |
| Sonic & Knuckles + Sonic The Hedgehog 3 | 1994 | genesis |
| Sonic & Tails 2 | 1994 | gg |
| Sonic 3D - Flickies' Island | 1996 | genesis, saturn |
| Sonic 3D - Flickies' Island | 2007 | wii |
| Sonic 3D Blast - Director's Cut | 1996 | genesis |
| Sonic 3D Blast 6 | 1997 | nes |
| Sonic 6 | 1998 | gb |
| Sonic Advance | 2001 | gba |
| Sonic Advance | 2015 | wiiu |
| Sonic Advance 2 | 2002 | gba, wiiu |
| Sonic Advance 2 | 2003 | gba |
| Sonic Advance 3 | 2004 | gba |
| Sonic Advance 3 | 2016 | wiiu |
| Sonic Adventure | 1998 | dreamcast, ps3, xbox360 |
| Sonic Adventure - Limited Edition | 1999 | dreamcast |
| Sonic Adventure 2 | 2001 | dreamcast |
| Sonic Adventure 2 | 2012 | ps3, xbox360 |
| Sonic Adventure 2 - Battle | 2001 | gc |
| Sonic Adventure 7 | 1999 | gbc |
| Sonic Adventure 8 | 2000 | gbc |
| Sonic Adventure International | 1999 | dreamcast |
| Sonic Blast | 1996 | gg, sms |
| Sonic Boom - Shattered Crystal | 2014 | 3ds |
| Sonic CD | 2011 | ps3 |
| Sonic CD | 2011 | ps3 |
| Sonic CD | 1993 | segacd, xbox360 |
| Sonic Chaos | 1993 | gg, sms |
| Sonic Classic Collection | 2010 | nds |
| Sonic Colors: Ultimate | 2021 | ps4, switch, xboxone |
| Sonic Colours | 2010 | nds |
| Sonic Colours | 2010 | wii |
| Sonic Crackers | 1994 | genesis |
| Sonic Forces | 2017 | ps4, switch, xboxone |
| Sonic Frontiers | 2022 | ps4, switch |
| Sonic Generations | 2011 | 3ds, ps3, xbox360 |
| Sonic Heroes | 2003 | gc, ps2, xbox |
| Sonic Heroes | 2012 | ps3 |
| Sonic Jam | 1997 | saturn |
| Sonic Jam 6 | 1998 | genesis |
| Sonic Mania | 2017 | ps4, switch, xboxone |
| Sonic Mania Plus | 2018 | ps4, switch, xboxone |
| Sonic Mega Collection | 2002 | gc |
| Sonic MegaMix | 2008 | segacd |
| Sonic Origins | 2022 | ps4, switch |
| Sonic Origins Plus | 2023 | ps4, switch |
| Sonic Rush | 2005 | nds |
| Sonic Rush Adventure | 2007 | nds |
| Sonic Superstars | 2023 | ps4, switch |
| Sonic The Hedgehog | 1991 | gg, sms |
| Sonic The Hedgehog | | nes |
| Sonic The Hedgehog - Genesis | 2006 | gba |
| Sonic The Hedgehog - Pocket Adventure | 1999 | ngpc |
| Sonic The Hedgehog - Triple Trouble | 1994 | gg |
| Sonic The Hedgehog 2 | 1992 | 3ds, arcade, genesis, xbox360 |
| Sonic The Hedgehog 3 | 2007 | wii |
| Sonic The Hedgehog 3 | 1993 | arcade |
| Sonic The Hedgehog 3 Limited Edition | 1994 | genesis |
| Sonic The Hedgehog 4 - Episode 2 | 2012 | ps3, xbox360 |
| Sonic Toon - Fire & Ice | 2016 | 3ds |
| Sonic Toon - Island Adventure | 2014 | 3ds |
| Sonic Unleashed | 2008 | ps2, ps3, wii, xbox360 |
| Sonic Unleashed | 2014 | ps3 |
| Sonic World Adventure | 2008 | ps3, xbox360 |