| Zanac | AS | 1987-10 |
| Unlicensed |
| Zanac | US | 1987-12 |
Compile | Commercial |
| Zapp | WORLD | |
| Demo |
| Zdey The Game | WORLD | 2021-09 |
Art'Cade | Prototype |
| Zelda Chuanshuo - San Shen Zhili | CN | 2004 |
| Unlicensed |
| Zelda Chuanshuo - Shenqi de Maozi | CN | 2006 |
| Unlicensed |
| Zelda Dream - Hourglass | WORLD | 2006 |
| Unlicensed |
| Zelda II - The Adventure of Link | EU | 1988-09-26 |
Nintendo | Commercial |
| Zelda II - The Adventure of Link | US | 1988-12-01 |
Nintendo | Commercial |
| Zelda no Densetsu 1 - The Hyrule Fantasy | JP | 1994-02 |
Nintendo | Commercial |
| Zen - Intergalactic Ninja | EU | 1993-03 |
Konami | Commercial |
| Zen - Intergalactic Ninja | US | 1993-03 |
Konami | Commercial |
| Zenbei Pro Basket | JP | 1989-07 |
Vic Tokai | Commercial |
| Zhanguo Fenghui | CN | |
| Unlicensed |
| Zhanguo Fengyun | CN | |
Shenzhen Jncota | Unlicensed |
| Zhanguo Qunxiong Zhuan | CN | |
| Unlicensed |
| Zhanguo Sichuan Sheng | TW | |
| Unlicensed |
| Zhanguo Wushuang | CN | |
| Unlicensed |
| Zhanshen Shijie | CN | |
Shenzhen Jncota | Unlicensed |
| Zhen Ben Xiyou Ji | TW | |
Asder | Unlicensed |
| Zhen Jia Hou Wang | CN | 1996 |
Waixing | Unlicensed |
| Zhen Shihun - Hun Zhi Liren | CN | |
Shenzhen Nanjing Technology | Unlicensed |
| Zhen Shihun - Wushidao Liezhuan | CN | |
| Unlicensed |
| Zhengba Shiji | CN | |
| Unlicensed |
| Zhengjiu Shiji | CN | 1996 |
| Unlicensed |
| Zhengzhan Tianxia | CN | |
| Unlicensed |
| Zhentian Shi Yongshi | CN | 2005 |
| Unlicensed |
| Zhili Pintu - Play Toy Pictures | CN | |
| Unlicensed |
| Zhong Guo Mahjong | CN | |
| Unlicensed |
| Zhong Zhuang Ji Bing | CN | 1990-02 |
| Unlicensed |
| Zhongguo Daheng - Maixiang Da Fuweng Zhi Lu | TW | |
| Unlicensed |
| Zhongguo Tu Baobao - China Rabbit | AS | |
| Unlicensed |
| Zhongguo Tu Baobao - China Rabbit | TW | |
| Unlicensed |
| Zhongguo Xiangqi - Chinese Chese | AS | |
TXC Corp | Unlicensed |
| Zhongguo Xiangqi - Chinese Chese | CN | |
| Unlicensed |
| Zhonghua Yingxiong | CN | |
| Unlicensed |
| Zhuangqiu Chuanshuo Hua Zhuang II - Ball Story | TW | 1993 |
Whirlwind Manu | Unlicensed |
| Zhuoyue Zhi Jian | CN | |
Henggedianzi | Unlicensed |
| Zippy Race | JP | 1985-07-18 |
Irem | Commercial |
| Zoda's Revenge - StarTropics II | EU | 1994-03 |
Nintendo | Commercial |
| Zoda's Revenge - StarTropics II | US | 1994-03 |
Nintendo | Commercial |
| Zoids - Chuuou Tairiku no Tatakai | JP | 1987-09 |
Toshiba EMI | Commercial |
| Zoids 2 - Zenebas no Gyakushuu | JP | 1989-01 |
Toshiba EMI | Commercial |
| Zoids Mokushiroku | JP | 1990-12-21 |
Tomy | Commercial |
| Zombie Apocalypse Right Now! | WORLD | |
| Unlicensed |
| Zombie Calavera Prologue | WORLD | 2010 |
The Mojon Twins | Prototype |
| Zombie Hunter | JP | 1987-07-03 |
Hi-Score Media Work | Commercial |
| Zombie Legacy | WORLD | |
| Prototype |
| Zombie Nation | US | 1991-09 |
Meldac | Commercial |
| Zombie Nation | US | 1991-01 |
Meldac | Prototype |
| Zombiehunter Bob | WORLD | |
| Unlicensed |
| Zooming Secretary | WORLD | 2011-12 |
Shiru | Unlicensed |
| Zui Youji Zhi Tang Sanzang | CN | |
Shenzhen Nanjing Technology | Unlicensed |
| Zuizhong Huanxiang 4 - Guang Yu An - Shuijing Fenzheng | CN | |
| Unlicensed |
| Zuizhong Huanxiang III | CN | |
| Unlicensed |
| Zuizhong Huanxiang X1 | CN | 2026-02 |
| Unlicensed |
| Zuizhong Huanxiang X2 | CN | 2004 |
| Unlicensed |
| Zuizhong Huanxiang X3 | CN | 2004 |
| Unlicensed |
| Zunou Senkan Galg | JP | 1985-12 |
dB-SOFT | Commercial |
| Zunou Senkan Galg | JP | 1985-12 |
dB-SOFT | Prototype |
| Zuqiu Ziaojiang | CN | |
| Unlicensed |