| 110-in-1 | AS | 1990 |
Supervision Entertainment | Unlicensed |
| 2-in-1 - Conan & Rygar | AS | 1990 |
| Unlicensed |
| 75 Bingo | AS | 1990 |
Sachen | Unlicensed |
| 76-in-1 | AS | 1990 |
| Unlicensed |
| 76-in-1 | CN | 1990 |
| Unlicensed |
| Bad Dudes vs. Dragon Ninja | EU | 1990 |
Ocean Software | Commercial |
| Block Force | TW | 1990 |
Hwang Shinwei | Unlicensed |
| Block Out | US | 1990 |
Technōs Japan | Prototype |
| Brush Roller | TW | 1990 |
RCM | Unlicensed |
| Castle of Deceit | US | 1990 |
Bunch Games | Unlicensed |
| Challenge of the Dragon | AS | 1990 |
Color Dreams | Unlicensed |
| Challenge of the Dragon | US | 1990 |
Color Dreams | Unlicensed |
| Chiller | AU | 1990 |
American Game Cartridges | Unlicensed |
| Chiller | US | 1990 |
AGCI | Prototype |
| Chiller | US | 1990 |
American Game Cartridges | Unlicensed |
| Chuck Yeager's Fighter Combat | US | 1990 |
Electronic Arts | Prototype |
| Corvette ZR-1 Challenge | EU | 1990 |
Milton Bradley | Commercial |
| Dancing Blocks | TW | 1990 |
Sachen | Unlicensed |
| Death Race | US | 1990 |
AGCI | Prototype |
| Deathbots | US | 1990 |
American Video Entertainment | Unlicensed |
| Die Bian - Incantation | TW | 1990 |
Bunch Games | Unlicensed |
| Double Strike - Aerial Attack Force | US | 1990 |
American Video Entertainment | Unlicensed |
| Dudes with Attitude | US | 1990 |
American Video Entertainment | Unlicensed |
| Exploding Fist | US | 1990 |
Tradewest | Commercial |
| Exploding Fist | US | 1990 |
Tradewest | Prototype |
| Exploding Fist | WORLD | 1990 |
Tradewest | Commercial |
| F-15 City War | ES | 1990 |
American Video Entertainment | Unlicensed |
| F-15 City War | TW | 1990 |
American Video Entertainment | Unlicensed |
| F-15 City War | US | 1990 |
American Video Entertainment | Unlicensed |
| Funblaster Pak | AU | 1990 |
HES Interactive | Unlicensed |
| Galactic Crusader | AS | 1990 |
Bunch Games | Unlicensed |
| Galactic Crusader | US | 1990 |
Bunch Games | Unlicensed |
| Grand Combat | AS | 1990 |
| Unlicensed |
| Honey Peach | TW | 1990 |
Sachen | Unlicensed |
| Idol Shisen Mahjong | JP | 1990 |
American Video Entertainment | Unlicensed |
| Impossible Mission II | AU | 1990 |
American Video Entertainment | Unlicensed |
| Impossible Mission II | US | 1990 |
American Video Entertainment | Unlicensed |
| Jurassic Boy 2 | TW | 1990 |
Sachen | Unlicensed |
| King Neptune's Adventure | US | 1990 |
Color Dreams | Prototype |
| King Neptune's Adventure | US | 1990 |
Color Dreams | Unlicensed |
| Kings of the Beach - Professional Beach Volleyball | US | 1990 |
Ultra Games | Commercial |
| Krazy Kreatures | US | 1990 |
American Video Entertainment | Prototype |
| Krazy Kreatures | US | 1990 |
American Video Entertainment | Unlicensed |
| Magic Jewelry | TW | 1990 |
RCM | Unlicensed |
| Magical Mathematics | AS | 1990 |
Sachen | Unlicensed |
| Magical Mathematics | TW | 1990 |
Sachen | Unlicensed |
| Mahjang Companion | JP | 1990 |
Hacker International | Unlicensed |
| Mahjang Companion | TW | 1990 |
Hacker International | Unlicensed |
| Mahjong Samit - Kabukicho Hen | JP | 1990 |
Hacker International | Unlicensed |
| Menace Beach | US | 1990 |
Color Dreams | Unlicensed |
| Millionaire | TW | 1990 |
Sachen | Unlicensed |
| Mindblower Pak | AU | 1990 |
Home Entertainment Suppliers | Unlicensed |
| Mission Cobra | US | 1990 |
Bunch Games | Unlicensed |
| Moon Ranger | US | 1990 |
Bunch Games | Unlicensed |
| Mr. Assy - Momoco & Hanako | AS | 1990 |
Sunsoft | Prototype |
| Nalara Superboy | KR | 1990 |
Color Dreams | Unlicensed |
| Nintendo World Championships 1990 | US | 1990 |
Nintendo | Commercial |
| P'Radikus Conflict | US | 1990 |
Color Dreams | Unlicensed |
| Papillon Gals | JP | 1990 |
Bunch Games | Unlicensed |
| Pesterminator - The Western Exterminator | US | 1990 |
Color Dreams | Unlicensed |
| Pinball Quest | AU | 1990 |
Jaleco | Commercial |
| Pipemania | AU | 1990 |
HES Interactive | Unlicensed |
| Poker Jijin - The World of Card Games | TW | 1990 |
Sachen | Unlicensed |
| Punch-Out!! | EU | 1990 |
Nintendo | Commercial |
| Punch-Out!! | US | 1990 |
Nintendo | Prototype |
| Puzzle | ES | 1990 |
American Video Entertainment | Unlicensed |
| Puzzle | TW | 1990 |
American Video Entertainment | Unlicensed |
| Puzzle | US | 1990 |
American Video Entertainment | Unlicensed |
| Pyramid | US | 1990 |
American Video Entertainment | Unlicensed |
| Pyramid - Cleopatra Kikiippatsu | JP | 1990 |
Disk Original Group (DOG) | Unlicensed |
| Pyramid II | TW | 1990 |
American Video Entertainment | Unlicensed |
| R.B.I. Baseball 2 | US | 1990 |
Tengen | Prototype |
| R.B.I. Baseball 2 | US | 1990 |
Tengen | Unlicensed |
| Robodemons | US | 1990 |
Color Dreams | Unlicensed |
| Silent Assault | AS | 1990 |
Color Dreams | Unlicensed |
| Silent Assault | US | 1990 |
Color Dreams | Unlicensed |
| Skull & Crossbones | KR | 1990 |
Tengen | Unlicensed |
| Skull & Crossbones | US | 1990 |
Tengen | Prototype |
| Skull & Crossbones | US | 1990 |
Tengen | Unlicensed |
| Super Contra DS | AS | 1990 |
| Unlicensed |
| Tagin' Dragon | US | 1990 |
Bunch Games | Unlicensed |
| Taro's Quest | US | 1990 |
Jaleco | Prototype |
| The Legend of Robin Hood | US | 1990 |
Arcadia Systems | Prototype |
| The Miracle Piano Teaching System | DE | 1990 |
The Software Toolworks | Commercial |
| The Miracle Piano Teaching System | FR | 1990 |
The Software Toolworks | Commercial |
| The Miracle Piano Teaching System | UK | 1990 |
The Software Toolworks | Commercial |
| Tiles of Fate | US | 1990 |
American Video Entertainment | Unlicensed |
| Twin Eagle | US | 1990 |
American Video Entertainment | Commercial |
| U-Force Power Games | US | 1990 |
TOSE | Prototype |
| Wally Bear and the No! Gang | US | 1990 |
American Video Entertainment | Unlicensed |
| 8 Eyes | US | 1990-01 |
Taxan USA Corp | Commercial |
| Bases Loaded II - Second Season | US | 1990-01 |
Jaleco | Commercial |
| Chris Evert & Ivan Lendl in Top Players' Tennis | US | 1990-01 |
Nintendo | Commercial |
| Clash at Demonhead | US | 1990-01 |
Vic Tokai | Commercial |
| David Crane's A Boy and His Blob - Trouble on Blobolonia | EU | 1990-01 |
Nintendo | Commercial |
| David Crane's A Boy and His Blob - Trouble on Blobolonia | US | 1990-01 |
Nintendo | Commercial |
| Demon Sword | US | 1990-01 |
Taito | Commercial |
| Double Dragon II - The Revenge | US | 1990-01 |
Acclaim Entertainment | Commercial |
| Ganbare Goemon Gaiden - Kieta Ougon Kiseru | JP | 1990-01 |
Konami | Commercial |
| Genghis Khan | US | 1990-01 |
Infogrames | Commercial |