| The Ren & Stimpy Show - Buckeroo$! | 1993 | nes |
| The Ren & Stimpy Show - Space Cadet Adventures | 1992 | gb |
| The Ren & Stimpy Show - Time Warp | 1994 | snes |
| The Ren & Stimpy Show - Veediots! | 1993 | gb |
| The Ren & Stimpy Show Presents - Stimpy's Invention | 1993 | genesis |
| Repugnant Bounty | 2022 | gbc |
| Rescue Heroes - Billy Blazes! | 2003 | gba |
| Rescue Time | 2020 | nes |
| Resq | 1994 | genesis |
| Revenge of Drancon | 1991 | gg |
| The Revenge of Shinobi | 2002 | gba |
| The Revenge of Shinobi | 2012 | ps3 |
| Revenge of the Bird King | 2020 | vita |
| The Revenge of the Smurfs | 2002 | gba |
| Revenge of the Wounded Dragons | 2009 | ps3 |
| Revita | 2022 | switch |
| Revolve | 2017 | xboxone |
| Rex Rocket | 2019 | xboxone |
| Rex Run | 2019 | gb |
| Rick Dangerous | 2013 | gba |
| Rick Dangerous | 2011 | genesis |
| Rick Dangerous 2 | 2011 | gba |
| Rick Dangerous 2 | 2018 | genesis |
| Rick Dangerous DX | 2025 | genesis |
| Rise of the Penguins | 2024 | gbc |
| Ristar | 1995 | gg |
| Ristar | 2006 | wii |
| Road Runner | 1993 | snes |
| Road Runner | 1985 | arcade |
| Road Runner's Death Valley Rally | 1992 | snes |
| Robbie Swifthand and the Orb of Mysteries | 2019 | ps4 |
| Robbit mon Dieu | 1999 | ps1 |
| RoboCop 2 | 1991 | gb, nes |
| RoboCop Versus The Terminator | 1994 | gb |
| RoboCop Versus The Terminator | 1993 | nes |
| Robocco Wars | 1991 | nes |
| Robocop | 1988 | arcade, gb, nes |
| Robocop 3 | 1992 | arcade, genesis, gg, nes, sms, snes |
| Robots | 2005 | gba, gc, nds, ps2, xbox |
| Robox | 2010 | wii |
| Rock'N'Roll Adventures | 2006 | ps2, wii |
| Rocket - Robot on Wheels | 1999 | n64 |
| Rocket Panda | 2024 | genesis |
| Rocket Power - Beach Bandits | 2002 | gba |
| Rocket Power - Dream Scheme | 2001 | gba |
| Rocketbirds - Hardboiled Chicken | 2013 | ps3, vita |
| Rocketbirds 2: Evolution | 2016 | ps4, vita |
| The Rocketeer | 1991 | nes |
| Rockheaven | | genesis |
| Rockman | 1987 | nes |
| Rockman | 2012 | wii, wiiu |
| Rockman & Crystal | 2016 | gba |
| Rockman & Forte | 2002 | gba |
| Rockman & Forte | 1998 | snes |
| Rockman & Forte - Mirai Kara no Chousensha | 1999 | ws |
| Rockman - Mega World | 1994 | genesis |
| Rockman 10 - Uchuu kara no Kyoui!! | 2010 | wii |
| Rockman 2 - Dr. Wily no Nazo | 1988 | nes |
| Rockman 2 - Dr. Wily no Nazo | 2012 | wii |
| Rockman 3 | | gbc |
| Rockman 3 - Dr. Wily no Saigo! | 1990 | nes |
| Rockman 3 - Dr. Wily no Saigo! | 2012 | wii |
| Rockman 4 - Aratanaru Yabou!! | 1991 | nes |
| Rockman 5 - Blues no Wana! | 1992 | nes |
| Rockman 5 - Blues no Wana! | | wii |
| Rockman 6 - Shijou Saidai no Tatakai!! | 1993 | nes |
| Rockman 7 - Shukumei no Taiketsu! | 2014 | wiiu |
| Rockman 8 - Metal Heroes | 1997 | saturn |
| Rockman 9 - Yabou no Fukkatsu!! | 2008 | wii |
| Rockman DX6 | 1998 | gbc |
| Rockman EXE WS | 2003 | wsc |
| Rockman Rockman | 2006 | psp |
| Rockman World | 1991 | gb |
| Rockman World 2 | 1991 | gb |
| Rockman World 3 | 1992 | gb |
| Rockman World 4 | 1993 | gb |
| Rockman World 5 | 1994 | gb |
| Rockman X | 2013 | wii, wiiu |
| Rockman X - Cyber Mission | 2000 | gbc |
| Rockman X2 | | wii |
| Rockman X2 - Soul Eraser | 2001 | gbc |
| Rockman X3 | | gbc |
| Rockman X3 | 2014 | wiiu |
| Rockman Zero | 2002 | gba |
| Rockman Zero | 2014 | wiiu |
| Rockman Zero 2 | 2015 | wiiu |
| Rockman Zero 3 | 2015 | wiiu |
| Rockman Zero 4 | 2015 | wiiu |
| Rocko's Modern Life - Spunky's Dangerous Day | 1994 | snes |
| Rockworld | | genesis |
| Rocman X | 1995 | nes |
| Rod Land | 1993 | gb |
| Rod-Land | 1990 | arcade, nes |
| Rodland | 1992 | gb, nes |
| Rolling Hare | 2025 | nes |
| Rolling Hare 2 | 2025 | nes |
| Rolling Thunder | | lynx |
| Rolo to the Rescue | 1993 | genesis |
| Ronin | 2016 | ps4 |
| Rootin' Tootin' Cowboy Wizard Lizards | 2025 | gbc |