| Discworld | 1996 | saturn |
| Discworld II - Missing Presumed...! | 1996 | ps1, saturn |
| Discworld II - Mortality Bytes! | 1997 | ps1 |
| Discworld II - Mortellement Votre | 1997 | ps1 |
| Discworld II - Vermutlich vermisst...! | 1997 | ps1 |
| Discworld Noir | 2000 | ps1 |
| Disease: Hidden Object | 2018 | switch |
| Disgaea Infinite | 2010 | psp |
| Disney Anna to Yuki no Joou - Olaf no Okurimono | 2015 | 3ds |
| The Disney Collection - QuackShot Starring Donald Duck + Castle of Illusion Starring Mickey Mouse | 1996 | genesis |
| Disney Fais Ton Histoire! Mulan | 1999 | ps1 |
| Disney Libro Animato Creativo - Mulan | 1999 | ps1 |
| Disney Planes - Fire & Rescue | | nds |
| Disney Princess - Magical Jewels | 2007 | nds |
| Disney Princess - My Fairytale Adventure | 2011 | 3ds, wii |
| Disney Princess - Royal Adventure | 2006 | gba |
| Disney The Princess and the Frog | 2009 | wii |
| Disney Tron - Evolution | 2010 | ps3, psp |
| Disney Villains Cursed Cafe | 2025 | switch |
| Disney's Aventura Interactiva - Mulan | 1999 | ps1 |
| Disney's Mulan - Story Studio | 1999 | ps1 |
| Disney's Story Studio - Mulan | 1999 | ps1 |
| Disney's Verhalenstudio - Mulan | 1999 | ps1 |
| Disney-Pixar Oben | 2009 | ps2, psp |
| Disney-Pixar Up | 2009 | psp |
| Disneys Interaktive Abenteuer - Mulan | 1999 | ps1 |
| Disorder 6 | 2013 | ps3, xbox360 |
| Dispatch | 2026 | switch |
| Distraint | 2019 | ps4 |
| Distraint - Deluxe Edition | 2019 | vita |
| Distraint 2 | 2020 | ps4 |
| Do I Pass | | gb |
| Doctor Lautrec and the Forgotten Knights | 2011 | 3ds |
| Doctor Who - Evacuation Earth | 2010 | nds |
| Doctor Who - Return to Earth | 2010 | wii |
| Doctor Who: The Edge of Reality | 2021 | ps4, switch, xboxone |
| Dog's Muck Island | 2021 | gb |
| Dogz | 2007 | ps2, wii |
| Doki Doki Literature Club Plus! | 2021 | ps4, switch, xboxone |
| Doki Doki Majo Shinpan! | 2007 | nds |
| Doki Majo Plus | 2009 | nds |
| Doki x Doki Sasete!! | 2001 | gbc |
| Doki-Doki Universe | 2013 | ps3, ps4, vita |
| Dokiou-ki | 1995 | ps1 |
| Doko Demo Hamster - Bi! Click Tankentai | 2002 | ps1 |
| Doko Demo Issho - Toro to Nagare-boshi | 2004 | ps2 |
| Doko Demo Issho - Watashi na Ehon | 2003 | ps2 |
| Doko e Iku no Anohi - Hikaru Ashita e | 2005 | ps2 |
| Doko made mo Aoku | 2002 | ps1 |
| Dollhouse | 2019 | ps4 |
| Dollhouse | 2021 | switch |
| Dominus | 1993 | genesis |
| Don Bluth Presents Dragon's Lair Trilogy | 2010 | wii |
| Don't Call Me Mama But Yes I Am Your Mama | 2019 | gb |
| Donut County | 2018 | ps4, switch, xboxone |
| Dora the Explorer - Dora Saves the Mermaids | 2004 | nds |
| Dora the Explorer - Dora's World Adventure! | 2006 | gba |
| Dora the Explorer - Super Star Adventures! | 2004 | gba |
| Doraemon - Minna de Asobou! Miniland | 2003 | gc |
| Dordogne | 2023 | switch |
| Dot Hack Akusei Hen'i Vol. 2 | 2003 | ps2 |
| Dot Hack Part 2 - Mutation | 2003 | ps2 |
| Double Dungeons | 2017 | wiiu |
| Double Reaction! Plus | 2004 | ps2 |
| Double Switch | 1994 | saturn, segacd |
| Double Wish | 2004 | ps2 |
| Doubutsu-jima no Chobigurumi | 2003 | gba |
| Doug - La Grande Aventure | 2001 | gbc |
| Doug's Big Game | 2000 | gbc |
| Doukoku Soshite | 1998 | saturn |
| Doukoku Soshite | 2019 | switch |
| Doukyuusei | 1995 | pcengine |
| Doukyuusei - if | 1996 | saturn |
| Doukyuusei 2 | 1996 | pcfx, ps1, saturn, snes |
| Dousoukai 2 - Again & Refrain | 2002 | dreamcast |
| Dr. Rin ni Kiite Mite! Koi no Happy Four Seasons | 2002 | ps1 |
| Dr. Rin ni Kiitemite! - Koi no Rin Fuusui | 2002 | gbc |
| Dr. Seuss - How the Grinch Stole Christmas! | 2004 | nds |
| Dr. Slump Arale-chan | 2008 | nds |
| Dracula - A Ressurreicao | 2001 | ps1 |
| Dracula - Crazy Vampire | 2001 | gbc |
| Dracula - La Risurrezione | 2001 | ps1 |
| Dracula - Resurreccion | 2001 | ps1 |
| Dracula - Resurrection | 2001 | ps1 |
| Dracula - The Last Sanctuary | 2002 | ps1 |
| Dracula - The Resurrection | 2001 | ps1 |
| Dracula - The Undead | 1992 | lynx |
| Dracula 2 - The Last Sanctuary | 2002 | ps1 |
| Dracula Unleashed | 1993 | segacd |
| DragoDino | 2018 | xboxone |
| Dragon Ball - Le Secret du Dragon | 1990 | nes |
| Dragon Ball - Shen Long no Nazo | 1986 | nes |
| Dragon Buster II - Yami no Fuuin | 1989 | nes |
| Dragon Knight II | 1992 | pcengine |
| Dragon Lore - The Legend Begins | 1995 | 3do |
| Dragon Power | 1988 | nes |
| Dragon Quest VII - Fragments of the Forgotten Past | 2016 | 3ds |
| Dragon Slayer - Eiyuu Densetsu | 1994 | genesis |
| Dragon Tales - Dragonseek | 2000 | ps1 |
| Dragon's Lair | 1990 | 3do, genesis, jaguarcd, nes, segacd |