| Simple 2000 Series Vol. 106 - The Block Kuzushi Quest - Dragon Kingdom | 2006 | ps2 |
| Simple 2000 Series Vol. 116 - The Neko-mura no Hitobito - Pug Daikan no Akugyou Zanmai | 2007 | ps2 |
| Simple 2000 Series Vol. 16 - The Sniper 2 - Akumu no Juudan | 2004 | ps2 |
| Simple 2000 Series Vol. 28 - The Bushidou - Tsujigiri Ichidai | 2003 | ps2 |
| Simple 2000 Series Vol. 5 - The Block Kuzushi Hyper | 2002 | ps2 |
| Simple 2000 Series Vol. 51 - The Senkan | 2004 | ps2 |
| Simple 2000 Series Vol. 52 - The Chikyuu Shinryakugun - Space Raiders | 2004 | ps2 |
| Simple 2000 Series Vol. 56 - The Survival Game | 2004 | ps2 |
| Simple 2000 Series Vol. 60 - The Tokusatsu Henshin Hero | 2004 | ps2 |
| Simple 2000 Series Vol. 64 - The Splatter Action | 2004 | ps2 |
| Simple 2000 Series Vol. 73 - The Saiyuu Touenden | 2005 | ps2 |
| Simple 2000 Series Vol. 83 - The Konchuu Saishuu | 2005 | ps2 |
| Simple 2000 Series Vol. 89 - The Party Game 2 | 2005 | ps2 |
| Simple 2500 Series Portable Vol. 13 - The Akuma Hunters - Exorsister | 2009 | psp |
| Simple 2500 Series Portable Vol. 6 - The Sensha | 2006 | psp |
| Simple 2500 Series Portable!! Vol. 12 - The Hohei 2 - Senyuu yo, Sakini Ike | 2009 | psp |
| Simple 2500 Series Portable!! Vol. 5 - The Block Kuzushi Quest - Dragon Kingdom | 2009 | psp |
| Simple 2960 Tomodachi Series Vol. 2 - The Block Kuzushi | 2003 | gba |
| Simple Character 2000 Series Vol. 15 - Cyborg 009 - The Block Kuzushi | 2002 | ps1 |
| Simple Character 2000 Series Vol. 16 - Gamba no Bouken - The Puzzle Action | 2003 | ps1 |
| Simple Character 2000 Series Vol. 17 - Sentou Mecha Xabungle - The Race in Action | 2003 | ps1 |
| Simple DS Series Vol. 31 - The Chou Dangan!! Custom Sensha | 2008 | nds |
| Simple Series Vol. 1 - The Block Kuzushi neo | 2008 | wii |
| Simple Wii Series Vol. 5 - The Block Kuzushi | 2008 | wii |
| Simple Wii Series Vol. 6 - The Wai Wai Combat | 2008 | wii |
| The Simpsons - Hit & Run | 2003 | gc, ps2, xbox |
| Sir Lancelot | 1984 | a2600 |
| Sir Lancelot | 1983 | col |
| Siren | 2003 | ps2 |
| Sitio do Picapau Amarelo | 1997 | sms |
| Sitting Ducks | 2003 | gba, ps1, ps2 |
| Skate Boy | 1992 | nes |
| Skeet Shoot | 1981 | a2600 |
| Skeleton Warriors | 1996 | ps1 |
| Skindiver | 1983 | a2600 |
| Skorb | 2016 | wiiu |
| Skuljagger - Revolt of the Westicans | 1992 | snes |
| Skull & Crossbones | | genesis |
| Sky Diver | 1978 | a2600, arcade |
| Sky Diver ~ Dare Diver | 1979 | a2600 |
| Sky Odyssey | 2000 | ps2 |
| Sky Skipper | 1983 | a2600 |
| SkyGunner | 2002 | ps2 |
| SkyPeace | 2014 | 3ds |
| Skyblazer | 1994 | snes |
| Skydiver | 1982 | a2600 |
| Skypeace | 2018 | switch |
| Skyscraper | 2008 | ps2, wii |
| Slain: Back from Hell | 2016 | ps4, vita, xboxone |
| Slain: Back from Hell | 2017 | switch |
| Slam City with Scottie Pippen | 1994 | segacd |
| Slap Fight MD | 1993 | genesis |
| Slave Zero | 1999 | dreamcast |
| Sleigh Chase | 2025 | genesis |
| Slither | 1983 | col |
| Sloshed! | 1986 | astrocade |
| Slot Racers | 1978 | a2600 |
| Slot Racers ~ Maze | 1978 | a2600 |
| Slurpy | 1984 | col |
| Sly 2 - Band of Thieves | 2004 | ps2 |
| Sly 3 - Honor Among Thieves | 2005 | ps2 |
| Sly 3 - Honour Among Thieves | 2005 | ps2 |
| Sly Cooper - Jeonseolui Bibeobseoreul Chajaseo | 2003 | ps2 |
| Sly Cooper 2 - Goedo Brothers Daejakjeon! | 2005 | ps2 |
| Sly Cooper 3 - Choehu-ui Daedo | 2005 | ps2 |
| Sly Cooper and the Thievius Raccoonus | 2002 | ps2, vita |
| Sly Raccoon | 2003 | ps2 |
| Small Soldiers | 1998 | ps1 |
| Smash | 1979 | arcade |
| Smithereens | 1982 | o2 |
| Smurf - Rescue in Gargamel's Castle | 1982 | a2600, col |
| The Smurfs | 2015 | 3ds |
| Snacks'n Jaxson | 1984 | arcade |
| Snail Mail | 2011 | wii |
| Snail Maze II | 2024 | genesis |
| Snake Den | 2014 | wiiu |
| Snake Off | 2022 | nes |
| Snakeball | 2007 | ps3 |
| Snakeybus | 2020 | ps4 |
| Snakeybus | 2020 | switch |
| Snaky Pocket | 2024 | gb |
| Snapper | 1990 | arcade |
| Snezhnaja Koroleva | | arcade |
| The Sniper 2 | 2002 | ps2 |
| Snoopy DS - Snoopy to Nakama-tachi ni Ai ni Ikou! | 2008 | nds |
| Snoopy and the Red Baron | 1983 | a2600 |
| Snow Ball | 2020 | lynx |
| Snow Bros. Jr | 1991 | gb |
| Snowball | 2017 | wiiu |
| Soccer | 1973 | arcade |
| Soccer Bashi | 2011 | wii |
| Soccer Kid | 1993 | snes |
| Socket | 1994 | genesis |
| Socks the Cat Rocks the Hill | 2018 | snes |
| Sol Divide: Sword of Darkness | 2018 | switch |
| SolSeraph | 2019 | switch, xboxone |
| Solar Fox | 1983 | a2600 |
| Solar Fox | 1981 | arcade |
| Solar Jetman | 1990 | arcade |
| Solar Storm | 1983 | a2600 |