| Super James Pond | US | 1991 |
Ocean Software | Commercial |
| Super James Pond | US | 1991 |
Ocean Software | Prototype |
| SimCity | JP | 1991-04-26 |
Nintendo | Commercial |
| Super Professional Baseball | JP | 1991-05-17 |
Jaleco | Commercial |
| Super Stadium | JP | 1991-07-02 |
Romstar | Commercial |
| Super Ultra Baseball | JP | 1991-07-12 |
Culture Brain | Commercial |
| Super R-Type | JP | 1991-07-13 |
Nintendo | Commercial |
| Shodan Morita Shougi | JP | 1991-08 |
SETA | Commercial |
| SimCity | US | 1991-08-23 |
Nintendo | Commercial |
| Super Mario World | US | 1991-08-23 |
Nintendo | Commercial |
| Super Mario World | US | 1991-08-23 |
Nintendo | Prototype |
| Super Tennis - World Circuit | JP | 1991-08-30 |
Nintendo | Commercial |
| Super Bases Loaded | US | 1991-09 |
Jaleco | Commercial |
| Super Bases Loaded | US | 1991-09 |
Jaleco | Prototype |
| Super R-Type | US | 1991-09 |
Nintendo | Commercial |
| Super Sangokushi II | JP | 1991-09-15 |
Koei | Commercial |
| Super E.D.F | JP | 1991-10-25 |
Jaleco | Commercial |
| Super Ghouls 'N Ghosts | US | 1991-11 |
Capcom | Commercial |
| Super Ghouls 'N Ghosts | US | 1991-11 |
Capcom | Prototype |
| Super Tennis | US | 1991-11 |
Nintendo | Commercial |
| Super Baseball Simulator 1.000 | US | 1991-12 |
Culture Brain | Commercial |
| Super Castlevania IV | US | 1991-12 |
Konami | Commercial |
| Super Nobunaga no Yabou - Bushou Fuuunroku | JP | 1991-12 |
Koei | Commercial |
| Super Off Road | US | 1991-12 |
Software Creations | Commercial |
| Super Formation Soccer | JP | 1991-12-13 |
Nintendo | Commercial |
| Super Wagyan Land | JP | 1991-12-13 |
Namco | Commercial |
| Super Fire Pro Wrestling | JP | 1991-12-20 |
Human | Commercial |
| SD Gundam Gaiden - Knight Gundam Monogatari - Ooinaru Isan | JP | 1991-12-21 |
Angel | Commercial |
| Super Chinese World | JP | 1991-12-28 |
Culture Brain | Commercial |
| SimEarth - The Living Planet | JP | 1991-12-29 |
FCI | Commercial |