| Red Baron | | o2 |
| Red Baron | 2005 | ps2 |
| Red Baron Arcade | 2009 | ps3 |
| Refrain Love - Anata ni Aitai | 1997 | ps1, saturn |
| Refrain Love 2 | 1999 | ps1 |
| Rei Fighter Gekitsui Senki | 2003 | gc |
| Reishiki Kanjou Sentouki | 2004 | ps2 |
| Reishiki Kanjou Sentouki - Seikuuou | 2007 | psp |
| Reishiki Kanjou Sentouki Ni | 2006 | ps2 |
| Reishiki Kanjou Sentouki Ni | | psp |
| Repetto Paris Ballerina | 2010 | wii |
| Rescue - The Embassy Mission | 1990 | nes |
| A Ressha de Ikou | 1991 | nes |
| A Ressha de Ikou 2001 | 2001 | ps2 |
| A Ressha de Ikou 4 - Evolution | 1994 | ps1 |
| A Ressha de Ikou 4 - Evolution Global | 1995 | ps1 |
| A Ressha de Ikou DS | 2009 | nds |
| A Ressha de Ikou MD | 1992 | genesis |
| Restaurant Dream | 1999 | ps1 |
| Return to PopoloCrois - A Story of Seasons Fairytale | 2016 | 3ds |
| Reus | 2016 | ps4, xboxone |
| Riding Academy 2 | 2010 | nds |
| Riding Stables 3D | 2012 | 3ds |
| Riding Star 3 | 2007 | nds |
| Rijexamen Training - Code de la Route | 2004 | nds |
| Rikujou Boueitai Mao-chan | 2003 | ps1 |
| Ringling Bros. and Barnum & Bailey | 2009 | wii |
| Ringling Bros. and Barnum & Bailey - It's My Circus - Elephant Friend | 2004 | nds |
| Rinne no Lagrange - Kamogawa Days - Game & OVA Hybrid Disc | 2013 | ps3 |
| River King - A Wonderful Journey | 2006 | ps2 |
| Road to Guangdong | 2020 | ps4, switch |
| Robot x Robot | 1999 | ps1 |
| Robotech - Crystal Dreams | 1998 | n64 |
| Roger Lemerre - La Selection des Champions 2003 | 2002 | ps2, xbox |
| Roger Lemerre - La Selection des Champions 2004 | 2004 | ps2, xbox |
| Roger Lemerre - La Selection des Champions 2005 | 2004 | ps2 |
| RollerCoaster Tycoon | 2003 | xbox |
| RollerCoaster Tycoon 3D | 2012 | 3ds |
| RollerCoaster Tycoon Adventures | 2018 | switch |
| RollerCoaster Tycoon Classic | 2024 | switch |
| RollerCoaster World | 2003 | ps2 |
| Rollercoaster Park | 2004 | nds |
| Roommania 203 | 2000 | dreamcast, ps2 |
| Roommate - Inoue Ryouko | 1997 | ps1, saturn |
| Roommate Simulator | 2023 | gb |
| Roommate W - Futari | 1999 | saturn |
| Roots of Pacha | 2023 | ps4, switch |
| Rune Factory 2 - A Fantasy Harvest Moon | 2008 | nds |
| Rune Factory 3 - A Fantasy Harvest Moon | 2009 | nds |
| Rune Factory 3 Special | 2023 | switch |
| Rune Factory 4 Special | 2019 | switch |
| S.L.A.I. - Steel Lancer Arena International | 2005 | ps2 |
| The Saddle Club | 2010 | wii |
| Safar'Wii | 2008 | wii |
| Saikin Koi Shiteru | 2009 | nds |
| Sailing | 1993 | cdi |
| Saka Tsuku DS - World Challenge 2010 | 2010 | nds |
| Sakuna: Of Rice and Ruin | 2020 | ps4, switch |
| Sakura Taisen 2 - Kimi, Shinitamou Koto Nakare | 1998 | dreamcast, saturn |
| Sakura Taisen V - Saraba Itoshiki Hito yo | 2005 | ps2 |
| Sally's Salon | 2008 | nds |
| Sam Power - Handyman | 2004 | nds |
| Sam Power - Policeman | 2004 | nds |
| Sangokushi 12 with Power-Up Kit | 2013 | ps3, wiiu |
| Sangokushi Retsuden - Ransei no Eiyuutachi | 1991 | genesis |
| Sangokushi VI | 1998 | dreamcast, ps1 |
| Sangokushi X | 2005 | ps2 |
| SatelliTV | 1998 | ps1 |
| Satisfashion - Rock the Runway | 2004 | nds |
| Satisfashion - Rock the Runway | 2010 | wii |
| Savage Skies | 2002 | ps2 |
| Sea Farm - Iruka to Watashi no Showtime | 2009 | wii |
| Sea Park Tycoon | 2004 | nds |
| Sea Trader - Rise of Taipan | 2003 | gba |
| Seaman | 2000 | dreamcast |
| Seaman - Kindan no Pet - Kanzenban | 2003 | ps2 |
| Seaman 2 - Pekin Genjin Ikusei Kit | 2007 | ps2 |
| Secret Story - Le Jeu Officiel de l'Emission | 2004 | nds |
| Sega Saturn de Hakken!! Tamagotchi Park | 1998 | saturn |
| Sengoku Cyber - Fujimaru Jigokuhen | 1995 | ps1 |
| Sennen Kazoku | 2005 | gba |
| Senran Kagura: Reflexions | 2017 | switch |
| Sentimental Graffiti | 1998 | saturn |
| Sentimental Graffiti - Yakusoku | 2003 | dreamcast |
| Sento Monogatari - Sono I | 1995 | 3do |
| Sento Monogatari - Sono I | 1996 | ps1 |
| Sento Monogatari Sono I | 1995 | saturn |
| Sentou Kokka Kai - New Operations | 2005 | ps2 |
| Sentou Yousei Yukikaze - Yousei no Mau Sora | 2003 | xbox |
| Serial Experiments Lain | 1998 | ps1 |
| The Settlers | 2007 | nds |
| Seventh Cross | 1998 | dreamcast |
| Seventh Cross Evolution | 2000 | dreamcast |
| Shelter Generations | 2018 | switch |
| Shepherd's Crossing | 2003 | ps2 |
| Shepherd's Crossing 2 DS | 2010 | nds |
| Shichuu Suimei Pitagraph | 1995 | ps1 |
| Shichuu Suimei Pitagraph | 1996 | saturn |
| Shichuusuimei-gaku Nyuumon - Shin Tougenkyou | 1995 | snes |
| Shiki-Tei | 2008 | ps3 |