| We're Back! - A Dinosaur's Story | 1993 | gb |
| Wenjia | 2018 | xboxone |
| Werewolf - The Last Warrior | 1990 | nes |
| Western Express | 1986 | arcade |
| Whac-a-Critter | 1993 | genesis |
| Whack 'n' Roll | 1998 | n64 |
| Where Are My Friends? | 2018 | xboxone |
| Where the Wild Things Are - The Videogame | 2009 | ps3 |
| Whipseey and the Lost Atlas | 2019 | xboxone |
| Whomp 'Em | 1991 | nes |
| Wicked Plague | 2025 | gbc |
| Wickie und die Starken Maenner | 2004 | nds |
| Widget | 1992 | nes |
| Wik and the Fable of Souls | 2005 | xbox360 |
| The Wild Thornberrys - Chimp Chase | 2001 | gba |
| The Wild Thornberrys - Rambler | 2000 | gbc |
| Wild Woody | 1995 | segacd |
| Wile E's Revenge | 1993 | snes |
| Willy Wombat | 1997 | saturn |
| Wily Tower | 1984 | arcade |
| Wink and the Broken Robot | | gbc |
| Winnie the Pooh's Rumbly Tumbly Adventure & Rayman 3 | 2006 | gba |
| Winter in Blue Mountain | 2012 | nds |
| Winx Club - Join the Club | 2007 | psp |
| WireWay | 2009 | nds |
| Witch n' Wiz | 2025 | genesis |
| Witchcrafty | 2021 | vita |
| Witchscape | 2024 | gb |
| Witty Cat | 1992 | svision |
| Wiz 'N' Liz | 1993 | genesis |
| Wiz 'n' Liz - The Frantic Wabbit Wescue | 1993 | genesis |
| The Wizard of Oz | 1993 | snes |
| Wizards & Warriors | 1987 | nes |
| Wizards & Warriors III - Kuros...Visions of Power | 1992 | nes |
| Wizards & Warriors X - The Fortress of Fear | 1990 | gb |
| Wo Xiang Niao Niao | 2017 | nes |
| Woah Dave! | 2014 | 3ds, wiiu |
| Woah Dave! | 2015 | vita |
| Wolf Spirit | 2021 | nes |
| Wolfling | 2018 | nes |
| Wolverine | 1991 | nes |
| Wolverine - Adamantium Rage | 1994 | genesis, snes |
| Wonder Boy | 1990 | gg |
| Wonder Boy | 1986 | arcade, sg1000, sms |
| Wonder Boy - The Dragon's Trap | 1992 | gg |
| Wonder Boy III - Monster Lair | 1988 | arcade, genesis, pcengine |
| Wonder Boy III - Monster Lair | | wii |
| Wonder Boy III - The Dragon's Trap | 1992 | gg |
| Wonder Boy III - The Dragon's Trap | 1989 | pcengine, sms |
| Wonder Boy in Monster Land | 1988 | sms |
| Wonder Boy in Monster World | 1991 | genesis, sms |
| Wonder Boy in Monster World | 1992 | genesis |
| Wonder Dog | 1992 | segacd |
| Wonder Rabbit | 2003 | nes |
| Wonderland Dizzy | 1991 | nes |
| Wooden Sen'SeY | 2014 | wiiu |
| Woodle Tree Adventures | 2019 | xboxone |
| Woodle Tree Adventures 2 | 2020 | xboxone |
| Woodpecker | 1981 | arcade |
| Woody Woodpecker | 2001 | gbc |
| Woody Woodpecker in Crazy Castle 5 | 2002 | gba |
| Wrath of the Black Manta | 1990 | nes |
| Wreck-It Ralph | 2012 | 3ds, nds |
| Wuppo | 2017 | ps4, xboxone |
| X-Men | 1993 | genesis |
| X-Men | 1994 | gg |
| X-Men - Gamemaster's Legacy | 1994 | gg |
| X-Men - Mojo World | 1996 | gg, sms |
| X-Men 2 - Clone Wars | 1995 | genesis |
| Xain'd Sleena | 1986 | arcade |
| Xardion | 1992 | snes |
| Xena - Warrior Princess | 2006 | ps2 |
| Xenon Valkyrie+ | 2018 | xboxone |
| Xexyz | 1990 | nes |
| Xia-Xia | 2012 | nds |
| Xingqiu Dazhan II - Kelong Ren Zhanyi | | gbc |
| Xitian Qujing - Journey to the West | 1994 | nes |
| YakOnTaks | 2025 | gba |
| Yakari - The Mystery of Four Seasons | 2015 | 3ds |
| Yami no Shigotonin Kage | 1990 | nes |
| Yanjamaru | 1986 | arcade |
| Yaobai Senxigang | | gba |
| Yars Rising | 2024 | ps4, switch |
| YesterMorrow | 2020 | ps4, switch, xboxone |
| Yo! Noid | 1990 | nes |
| Yo! Noid | 1990 | arcade |
| YoYo Spell | 1992 | arcade |
| Yogi Bear | 1995 | snes |
| Yogi Bear - Cartoon Capers | 1994 | genesis |
| Yogi Bear - The Video Game | 2010 | nds |
| Yogi Bear in Yogi Bear's Goldrush | 1994 | gg |
| Yogi Bear's Cartoon Capers | 1994 | snes |
| Yogi Bear's Gold Rush | 1994 | gb |
| Yogi's Frustration | 1983 | intv |
| Yokai Ninja | 2025 | sms |
| Yooka-Laylee | 2017 | ps4, switch, xboxone |
| Yooka-Laylee and the Impossible Lair | 2019 | ps4, switch, xboxone |
| Yoshi New Island | 2014 | 3ds |
| Yoshi Sample | | gba |
| Yoshi Wool World | 2015 | wiiu |