| Super Putty Squad | 2017 | switch |
| Super Rescue RoboCop 3 | 1991 | nes |
| Super Rider | 1983 | arcade |
| Super Robin Hood | 1993 | nes |
| Super Rude Bear Resurrection | 2017 | ps4 |
| Super Sami Roll | 2021 | switch |
| The Super Shinobi | | nes |
| The Super Shinobi | | wii |
| The Super Shinobi II | 1993 | genesis |
| The Super Shinobi II | | wii |
| Super Skull Smash GO! 2 Turbo | 2018 | vita |
| Super Smash Bros. Brawl | 2008 | wii |
| Super Sonic 5 | 1997 | nes |
| Super Star Wars | 1992 | ps4, snes, vita |
| Super Star Wars - Return of the Jedi | 1994 | gb, gg, snes, wii |
| Super Tempo | 1998 | saturn |
| Super Thor Quest | 2014 | snes |
| Super Trio | 1994 | arcade |
| Super Troll Islands | 1994 | snes |
| Super Troll Islands - Shiawase o Ageru | 1994 | snes |
| Super Turrican | 1993 | nes |
| Super Turrican Collection | 2022 | snes |
| Super Uwol | 2016 | nes |
| Super Wagyan Land | 1991 | snes |
| Super Wagyan Land 2 | 1993 | snes |
| Super Wonder Boy | | wii |
| Super Wonder Boy - Monster World | 2014 | wii |
| Super Yume Kojo | 1987 | fds |
| Superfrog | 1994 | cd32 |
| Superfrog HD | 2013 | ps3, vita |
| Superman | 1997 | gb |
| Superman | 1987 | nes |
| Superman - The Man of Steel | 1993 | gg, sms |
| Surf Ninjas | 1993 | gg |
| Sushi Nights | 2024 | sms |
| Sushi the Cat | 2007 | gba |
| Sutte Hakkun | 1998 | snes, wiiu |
| Swamp Thing | 1992 | gb, nes |
| Swamp Thing | 1992 | genesis |
| The Swapper | 2014 | ps3, ps4, vita, wiiu |
| The Swapper | 2015 | xboxone |
| Swarm | 2011 | ps3, xbox360 |
| Switch or Die Trying | 2018 | xboxone |
| Switchblade II | 1992 | lynx |
| The Sword of Camelot | 2001 | ps1 |
| Syd of Valis | 1992 | genesis |
| Sydney Hunter - The Sacred Tribe | 2019 | sms |
| Sylvester & Tweety - Breakfast on the Run | 1998 | gbc |
| Sylvester & Tweety in Cagey Capers | 1994 | genesis |
| T2 - Terminator 2 - Judgment Day | 1993 | genesis |
| TORGMAN Adventures Pt. 1 | 2023 | nes |
| Tabaluga - Gruenland in Gefahr | 2008 | nds |
| Tadeo Jones | 2013 | vita |
| Tadeo Jones y el Manuscrito Perdido | 2014 | vita |
| Tail 'Gator | 1991 | gb |
| Taimumari: Complete Edition | 2020 | xboxone |
| Taito Memorial - Bubble Bobble | 2000 | gbc |
| Tak - Mojo Mistake | 2008 | nds |
| Tak - The Great Juju Challenge | 2005 | gba, nds |
| Tak 2 - The Staff of Dreams | 2004 | gba |
| Tak and the Power of Juju | 2003 | gba, gc, ps2 |
| Takahashi Meijin no Bouken-jima | 1986 | nes |
| Takahashi Meijin no Bouken-jima II | 1992 | gb |
| Takahashi Meijin no Bouken-jima II | 1991 | nes |
| Takahashi Meijin no Bouken-jima III | 1992 | gb, nes |
| Takahashi Meijin no Daibouken-jima II | 2014 | wii |
| Takahashi Meijin no Shin Bouken-jima | 1992 | pcengine |
| Takahashi Meijin no Shin Bouken-jima | | wii |
| Takeshi no Chousenjou | 1986 | nes |
| The Tale - Elrond no Eiyuu | 1988 | nes |
| The Tale of Despereaux | 2008 | nds, ps2 |
| The Tale of Despereaux | 2008 | wii |
| A Tale of Paper | 2020 | ps4 |
| TaleSpin | 1992 | genesis, gg |
| TaleSpin | 1991 | pcengine |
| Talent Not Included | 2017 | xboxone |
| Tales From Space - Mutant Blobs Attack!!! | 2012 | ps3, switch, vita, xbox360 |
| Tales from Space - About a Blob | 2011 | ps3 |
| Tales of Elastic Boy - Mission 1 | 2010 | wii |
| Talmit's Adventure | 1992 | genesis |
| Tama & Friends - Sanchoume Daibouken | 1989 | fds |
| Tamarin | 2020 | ps4 |
| Tamashii | 2019 | xboxone |
| Tandem: A Tale of Shadows | 2021 | ps4, switch |
| Tandem: A Tale of Shadows | 2021 | xboxone |
| Tanglewood | 2018 | genesis |
| Tarzan | 1999 | gbc, n64, ps1 |
| Tarzan - Lord of the Jungle | 1994 | gb, gg |
| Tarzan - Return to the Jungle | 2002 | gba |
| Tashiro Masashi no Princess ga Ippai | 1989 | nes |
| Tasmania Monogatari | 1990 | gb |
| Tasmania Story | 1991 | gb |
| Tasmanian Devil - Munching Madness | 1999 | gbc |
| Tatakae Genshijin 3 - Shuyaku wa Yappari Joe & Mac | 1994 | snes |
| Tatakae! Chou Robot Seimeitai Transformers - Convoy no Nazo | 1986 | nes |
| Tatsunoko Fighter | 1989 | pcengine |
| Taz Express | 2000 | n64 |
| Taz in Escape from Mars | 1994 | genesis, gg, sms |
| Taz-Mania | 1992 | gg |
| Taz-Mania 2 | 1997 | gb |