| Famidash | 2024 | nes |
| The Fancy Pants Adventures | 2011 | ps3 |
| The Fancy Pants Adventures | 2011 | xbox360 |
| Fancy World - Earth of Crisis | 1996 | arcade |
| Fantastic 4 - Flame On | 2005 | gba |
| Fantastic Dizzy | 1993 | genesis, gg, nes, sms |
| Fantasy World Dizzy | 2019 | jaguar |
| Far: Changing Tides | 2022 | switch |
| Fast Eddie | 1982 | a2600 |
| Faster, Harder, More Challenging Q*bert | 1983 | arcade |
| Fat Bobby | 1997 | lynx |
| Fatman & Slim | | ps2 |
| Faussete Amour | 1993 | pcengine |
| Feed IT Souls | 2023 | gbc |
| Feed The Monster | 2023 | gbc |
| Feist | 2016 | ps4, xboxone |
| Feline | 2021 | gba |
| Felix the Cat | 1992 | gb, nes |
| Felix the Cat | 2010 | genesis |
| Felix vs Jerry | 1995 | nes |
| Fenix Furia | 2016 | ps4, xboxone |
| Ferias Frustradas do Pica Pau | 1996 | genesis, sms |
| Fermi's Path | 2015 | xboxone |
| Fez | 2012 | ps3, ps4, switch, vita, xbox360 |
| The Fidgetts | 1993 | gb |
| The Fidgetts | 1997 | gb |
| Fido Dido | 1993 | genesis |
| Fiend Hunter | 1993 | pcengine |
| Fighter on the Path of Glory | 2024 | gbc |
| Fighting Simulator 2 in 1 - Flying Warriors | 1992 | gb |
| Filthy Kitchen | 2017 | nes |
| The Final Station | 2016 | ps4, switch, xboxone |
| Fire & Ice - The Daring Adventures of Cool Coyote | 1993 | cd32, sms |
| Fire Fighter | 1993 | gb |
| Firebeast | 1983 | arcade |
| Fireman | 1984 | col |
| Fireteam Rogue | 1995 | snes |
| Firework Thrower Kantaro's 53 Stations of the Toukaido | 1986 | nes |
| The First Tree | 2018 | switch, xboxone |
| Fix & Foxi - Episode 1 - Lupo | 2000 | gbc |
| Fix It Felix Jr | 2020 | gbc |
| Fix My Heart | 2023 | gbc |
| Fix-It Felix Jr | 2014 | genesis |
| The Flash | 1992 | gb |
| The Flash | 1993 | sms |
| Flashback | 2013 | ps3, xbox360 |
| Flashback - The Quest for Identity | 1995 | jaguar |
| Flea! | 2020 | nes |
| Flea! 2 | 2024 | nes |
| Flicky | 1984 | arcade, genesis, sg1000 |
| Flink | 1994 | cd32, genesis, segacd |
| The Flintstones | 1994 | gb |
| The Flintstones - Big Trouble in Bedrock | 2001 | gba |
| The Flintstones - Burgertime in Bedrock | 2000 | gbc |
| The Flintstones - King Rock Treasure Island | 1993 | gb |
| The Flintstones - The Rescue of Dino & Hoppy | 1991 | nes |
| The Flintstones - The Surprise at Dinosaur Peak | 1994 | nes |
| Flip & Flop | 1983 | arcade |
| Flip's Twisted World | 2010 | wii |
| Flipper & Lopaka | 2001 | gbc |
| Flockers | 2014 | ps4 |
| Flyhunter Origins | 2014 | vita |
| Flying Dragon - The Secret Scroll | 1989 | nes |
| Flying Warriors | 1991 | nes |
| For the Birds VI | 2021 | nes |
| Foregone | 2020 | ps4, switch |
| Forest Escape - A Knight's Quest | 2025 | sms |
| Fort Boyard | 2001 | gbc |
| Forward to the Sky | 2021 | switch |
| Four Sided Fantasy | 2016 | ps4, xboxone |
| Fox N Forests | 2018 | switch |
| Fox's Peter Pan & the Pirates - The Revenge of Captain Hook | 1991 | nes |
| Foxy Land | 2020 | genesis |
| FoxyLand | 2019 | vita |
| FoxyLand 2 | 2020 | vita |
| Foxyland | 2019 | xboxone |
| Frankenstein's Monster | 1983 | a2600 |
| Franklin's Great Adventures | 2006 | gba, nds |
| Frantic Flea | 1996 | snes |
| Frantic Fred | 1996 | arcade |
| Freak Boy | | n64 |
| Freedom Planet | 2014 | ps4, switch, wiiu |
| Freedom Planet 2 | 2024 | ps4, switch, xboxone |
| FreezeME | 2016 | wiiu |
| FreezeME | 2016 | xboxone |
| Fret Nice | 2010 | xbox360 |
| Fridge Fury | 2026 | sms |
| Frog | 2021 | nes |
| Frog Dude | 1993 | genesis |
| Frogger | 1991 | gg |
| Frogger - Ancient Shadow | 2005 | gc, ps2, xbox |
| Frogger Beyond | 2002 | gc, ps2, xbox |
| Frogger's Adventures 2 - The Lost Wand | 2002 | gba |
| Frogger's Journey - The Forgotten Relic | 2003 | gba |
| Frogs | 1978 | arcade |
| Frogun | 2022 | switch |
| Fru | 2016 | xboxone |
| Fudou Myouou Den | 1988 | nes |
| Full Metal Furies | 2018 | xboxone |
| Fumiko! | 2018 | xboxone |