| Super Strike Eagle | US | 1993-03 |
MicroProse | Commercial |
| Super Strike Gunner | EU | 1992-11 |
Activision | Commercial |
| Super Sudoku | WORLD | 2019 |
| Prototype |
| Super Sudoku | WORLD | 2019 |
| Unlicensed |
| Super Tekkyuu Fight! | JP | 1995-09-15 |
Banpresto | Commercial |
| Super Tennis | EU | 1992-06 |
Nintendo | Commercial |
| Super Tennis | US | 1991-11 |
Nintendo | Commercial |
| Super Tennis - World Circuit | JP | 1991-08-30 |
Nintendo | Commercial |
| Super Tetris 2 + Bombliss | JP | 1992-12-18 |
Bullet-Proof Software | Commercial |
| Super Tetris 2 + Bombliss Gentei Ban | JP | 1994-01-21 |
Bullet-Proof Software | Commercial |
| Super Tetris 3 | JP | 1994-12-16 |
Bullet-Proof Software | Commercial |
| Super Thor Quest | US | 2014 |
Piko Interactive | Unlicensed |
| Super Troll Islands | EU | 1994-02 |
American Softworks | Commercial |
| Super Troll Islands | US | 1994-02 |
American Softworks | Commercial |
| Super Troll Islands | US | 1994-02 |
American Softworks | Prototype |
| Super Troll Islands - Shiawase o Ageru | JP | 1994-03 |
American Softworks | Commercial |
| Super Trump Collection | JP | 1995-04-21 |
Bottom Up Interactive | Commercial |
| Super Trump Collection 2 | JP | 1996-07-19 |
Bottom Up Interactive | Commercial |
| Super Tsumeshougi 1000 | JP | 1994-12 |
Bottom Up Interactive | Commercial |
| Super Turrican | EU | 1993-05 |
Hudson Soft | Commercial |
| Super Turrican | JP | 1993-09-03 |
Hudson Soft | Commercial |
| Super Turrican | US | 1993-05 |
Hudson Soft | Commercial |
| Super Turrican 2 | EU | 1995-05 |
Ocean Software | Commercial |
| Super Turrican 2 | US | 1995-11 |
Ocean Software | Commercial |
| Super Turrican 2 | US | 1995-11 |
Ocean Software | Prototype |
| Super Turrican Collection | US | 2022 |
Strictly Limited Games | Commercial |
| Super Ultra Baseball | JP | 1991-07-12 |
Culture Brain | Commercial |
| Super Ultra Baseball 2 | JP | 1994-07-28 |
Culture Brain | Commercial |
| Super Uno | JP | 1993-11-12 |
Tomy | Commercial |
| Super Uno | JP | 1993-11-12 |
Tomy | Prototype |
| Super Valis - Akaki Tsuki no Otome | JP | 1992-03 |
Atlus | Commercial |
| Super Valis IV | US | 1993-02 |
Atlus | Commercial |
| Super Variable Geo | JP | 1995-07 |
TGL | Commercial |
| Super Volley II | JP | 1992-12-25 |
Ubisoft | Commercial |
| Super Wagyan Land | JP | 1991-12-13 |
Namco | Commercial |
| Super Wagyan Land 2 | JP | 1993-03-25 |
Namco | Commercial |
| Super Widget | EU | 1993-09 |
Atlus | Commercial |
| Super Widget | US | 1993-09 |
Atlus | Commercial |
| Super Widget | US | 1993-09 |
Atlus | Prototype |
| Super Wrestle Angels | JP | 1994-12-16 |
Imagineer | Commercial |
| Super Yakyuudou | JP | 1996-01 |
Banpresto | Commercial |
| Super Zugan - Hakotenjou kara no Shoutaijou | JP | 1994-02-11 |
Electronic Arts | Commercial |
| Super Zugan 2 - Tsukanpo Fighter | JP | 1994-12-30 |
J-Wing | Commercial |
| Super!! Pachinko | JP | 1994-07-29 |
I'Max | Commercial |
| Supercooked! | WORLD | |
SNESDEV | Unlicensed |
| Superman | US | 1994-08 |
Blizzard Entertainment | Demo |
| Supplication | WORLD | |
| Prototype |
| Sure Instinct | WORLD | 2021-09 |
Benjamin Schulte | Unlicensed |
| Sutobasu Yarou Show | JP | 1994-02 |
B-AI | Commercial |
| Sutte Hakkun | JP | 1998-08 |
Nintendo | Commercial |
| Suzuka 8 Hours | JP | 1993-10-15 |
Namco | Commercial |
| Suzuka 8 Hours | US | 1994-05 |
Namco | Commercial |
| Suzuki Aguri no F-1 Super Driving | JP | 1992-07-17 |
Altron | Commercial |
| Sword Maniac | JP | 1994-02-11 |
Activision | Commercial |
| Sword World SFC | JP | 1993-08-06 |
T&E Soft | Commercial |
| Sword World SFC 2 - Inishie no Kyojin Densetsu | JP | 1994-07-15 |
T&E Soft | Commercial |
| Sydney Hunter and the Caverns of Death | WORLD | 2017 |
Collectorvision Games | Unlicensed |
| Sylvester and Tweety | US | 1993 |
Sunsoft | Prototype |
| Syndicate | EU | 1995-01 |
Bullfrog Productions | Commercial |
| Syndicate | EU | 1995-01 |
Bullfrog Productions | Prototype |
| Syndicate | JP | 1995-05-19 |
Bullfrog Productions | Commercial |
| Syndicate | US | 1995-12 |
Bullfrog Productions | Commercial |
| Syvalion | EU | 1993 |
JVC | Commercial |
| Syvalion | EU | 1993 |
JVC | Prototype |
| Syvalion | JP | 1992-07-24 |
JVC | Commercial |
| sNESert Golfing | WORLD | 2022-10-15 |
RainWarrior | Unlicensed |
| seaQuest DSV | EU | 1995-07-27 |
Sculptured Software | Commercial |
| seaQuest DSV | US | 1995-01 |
Sculptured Software | Commercial |