| Hissatsu Shigoto Nin | JP | 1990-12 |
Banpresto | Commercial |
| Jackie Chan's Action Kung Fu | US | 1990-12 |
Hudson Soft | Commercial |
| Jiqi Zhanshi Gaoda | CN | 1990-12 |
| Unlicensed |
| Little Ninja Brothers | US | 1990-12 |
Culture Brain | Commercial |
| Magical Kid's Doropie | JP | 1990-12 |
Vic Tokai | Commercial |
| Magical Kid's Doropie | JP | 1990-12 |
Vic Tokai | Prototype |
| Metal Flame - Psy Buster | JP | 1990-12 |
Jaleco | Commercial |
| MetalMech - Man & Machine | WORLD | 1990-12 |
Jaleco | Commercial |
| Musashi no Bouken | JP | 1990-12 |
Sigma Enterprises | Commercial |
| Nantettatte!! Baseball + Nantettatte!! Baseball - Ko-Game Cassette - OB All Star Hen | JP | 1990-12 |
Sunsoft | Commercial |
| Ninja Crusaders | US | 1990-12 |
Sammy Studios | Commercial |
| Ninja Crusaders | US | 1990-12 |
American Sammy | Prototype |
| Ninja Crusaders - Ryuuga | JP | 1990-12 |
Sammy Studios | Commercial |
| Nintendo World Cup | US | 1990-12 |
Nintendo | Commercial |
| North and South | US | 1990-12 |
Infogrames | Commercial |
| Pajama Hero - Nemo | JP | 1990-12 |
Capcom | Commercial |
| Perman | JP | 1990-12 |
Irem | Commercial |
| SD Gundam - Gachapon Senshi 3 - Eiyuu Senki | JP | 1990-12 |
Yutaka | Commercial |
| Saiyuuki World 2 - Tenjoukai no Majin | JP | 1990-12 |
Jaleco | Commercial |
| Shadow of the Ninja | US | 1990-12 |
Taito | Commercial |
| Shadow of the Ninja | US | 1990-12 |
Natsume | Demo |
| Super Mario Bros. + Duck Hunt + World Class Track Meet | US | 1990-12 |
Nintendo | Commercial |
| Super Mario Bros. + Duck Hunt + World Class Track Meet | US | 1990-12 |
Nintendo | Demo |
| Super Spike V'Ball + Nintendo World Cup | US | 1990-12 |
Nintendo | Commercial |
| Teenage Mutant Ninja Turtles | JP | 1990-12 |
Konami | Commercial |
| Teenage Mutant Ninja Turtles II - The Arcade Game | AS | 1990-12 |
| Unlicensed |
| Teenage Mutant Ninja Turtles II - The Arcade Game | US | 1990-12 |
Konami | Commercial |
| Teenage Mutant Ninja Turtles II - The Arcade Game | US | 1990-12 |
Konami | Demo |
| The Adventures of Rad Gravity | US | 1990-12 |
Activision | Commercial |
| The Adventures of Rad Gravity | US | 1990-12 |
Activision | Prototype |
| The Adventures of Rad Gravity | WORLD | 1990-12 |
Activision | Commercial |
| The Bard's Tale | JP | 1990-12 |
FCI | Commercial |
| The Bard's Tale | JP | 1990-12 |
FCI | Prototype |
| Thunder & Lightning | US | 1990-12 |
Romstar | Commercial |
| Turtle Ninja II | AS | 1990-12 |
| Unlicensed |
| Ultima - Quest of the Avatar | US | 1990-12 |
FCI | Commercial |
| Airwolf | EU | 1990-12-06 |
Acclaim Entertainment | Commercial |
| Ghostbusters II | EU | 1990-12-07 |
Activision | Commercial |
| Great Boxing - Rush Up | JP | 1990-12-07 |
Romstar | Commercial |
| Tecmo World Cup Soccer | JP | 1990-12-07 |
Tecmo | Commercial |
| Times of Lore | JP | 1990-12-07 |
Toho | Commercial |
| Famicom Top Management | JP | 1990-12-12 |
Koei | Commercial |
| Abarenbou Tengu | JP | 1990-12-14 |
Meldac | Commercial |
| DuckTales | EU | 1990-12-14 |
Capcom | Commercial |
| Klax | JP | 1990-12-14 |
Tengen | Commercial |
| Klax | US | 1990-12-14 |
Tengen | Prototype |
| Klax | US | 1990-12-14 |
Tengen | Unlicensed |
| Magical Doropie | AS | 1990-12-14 |
| Unlicensed |
| Mega Man 2 | EU | 1990-12-14 |
Capcom | Commercial |
| Wagyan Land 2 | JP | 1990-12-14 |
Namco | Commercial |
| Jumpin' Kid - Jack to Mame no Ki Monogatari | JP | 1990-12-19 |
Asmik | Commercial |
| Famista '91 | JP | 1990-12-21 |
Namco | Commercial |
| Jigoku Gokuraku Maru | JP | 1990-12-21 |
HAL Laboratory | Commercial |
| Sword Master | JP | 1990-12-21 |
Athena | Commercial |
| Zoids Mokushiroku | JP | 1990-12-21 |
Tomy | Commercial |
| New Ghostbusters II | JP | 1990-12-26 |
HAL Laboratory | Commercial |
| StarTropics | US | 1990-12-26 |
Nintendo | Commercial |
| Adventures of Lolo | EU | 1990-12-28 |
HAL Laboratory | Commercial |
| Contra | RU | 1990-12-28 |
| Unlicensed |
| Faxanadu | EU | 1990-12-28 |
Nintendo | Commercial |
| Probotector | EU | 1990-12-28 |
Konami | Commercial |