| Shockwave | US | 1991 |
American Game Cartridges | Unlicensed |
| SimCity | US | 1991 |
Nintendo | Prototype |
| Soap Panic | JP | 1991 |
Panesian | Unlicensed |
| Stakk'm | US | 1991 |
American Video Entertainment | Prototype |
| Strategist | AS | 1991 |
Sachen | Unlicensed |
| Strategist | TW | 1991 |
Sachen | Unlicensed |
| Street Gangs | EU | 1991 |
Infogrames | Commercial |
| Super Adventure Quests | EU | 1991 |
Codemasters | Unlicensed |
| Super Mario Bros. 4 | AS | 1991 |
| Unlicensed |
| Super Mario IV | AS | 1991 |
| Unlicensed |
| Super Pang | AS | 1991 |
Sachen | Unlicensed |
| Super Sports Challenge - Quattro Sports | EU | 1991 |
Camerica | Unlicensed |
| The Battle of Olympus | EU | 1991 |
Brøderbund Software | Commercial |
| The Fantastic Adventures of Dizzy | EU | 1991 |
Camerica | Unlicensed |
| The Fantastic Adventures of Dizzy | US | 1991 |
Camerica | Unlicensed |
| The Fantastic Adventures of Dizzy | US | 1991 |
Camerica | Prototype |
| The King of Kings - The Early Years | US | 1991 |
Wisdom Tree | Unlicensed |
| The Ultimate Stuntman | AS | 1991 |
Camerica | Unlicensed |
| The Ultimate Stuntman | EU | 1991 |
Camerica | Unlicensed |
| Turbo Racing | EU | 1991 |
Data East | Commercial |
| Ultimate League Soccer | EU | 1991 |
American Video Entertainment | Unlicensed |
| Venice Beach Volleyball | TW | 1991 |
American Video Entertainment | Unlicensed |
| Venice Beach Volleyball | US | 1991 |
American Video Entertainment | Prototype |
| Venice Beach Volleyball | US | 1991 |
American Video Entertainment | Unlicensed |
| Volley Ball | ES | 1991 |
American Video Entertainment | Unlicensed |
| War in the Gulf | BR | 1991 |
CCE | Unlicensed |
| War in the Gulf | ES | 1991 |
CCE | Unlicensed |
| War on Wheels | US | 1991 |
Jaleco | Prototype |
| War on Wheels | WORLD | 1991 |
Jaleco | Unlicensed |
| Willow | EU | 1991 |
Capcom | Commercial |
| Wonderland Dizzy | EU | 1991 |
Camerica | Prototype |
| Wonderland Dizzy | WORLD | 1991 |
Camerica | Unlicensed |
| Xybots | US | 1991 |
Atari | Prototype |
| Yuanshi Mali VII | AS | 1991 |
| Unlicensed |
| Advanced Dungeons & Dragons - Heroes of the Lance | US | 1991-01 |
FCI | Commercial |
| Advanced Dungeons & Dragons - Heroes of the Lance | US | 1991-01 |
FCI | Prototype |
| Fighting Hero | TW | 1991-01 |
NTDEC | Unlicensed |
| Fox's Peter Pan & the Pirates - The Revenge of Captain Hook | US | 1991-01 |
THQ | Commercial |
| Fun House | US | 1991-01 |
HiTech Software | Commercial |
| G.I. Joe - A Real American Hero | US | 1991-01 |
Taxan USA Corp | Commercial |
| G.I. Joe - The Atlantis Factor | US | 1991-01 |
Taxan USA Corp | Prototype |
| Jackie Chan | JP | 1991-01 |
Hudson Soft | Commercial |
| Kabuki - Quantum Fighter | US | 1991-01 |
HAL Laboratory | Commercial |
| Mahjong RPG Dora Dora Dora | JP | 1991-01 |
Natsume | Commercial |
| QIX | US | 1991-01 |
Taito | Commercial |
| Tecmo World Cup Soccer | EU | 1991-01 |
Tecmo | Commercial |
| The Hunt for Red October | AS | 1991-01 |
| Unlicensed |
| The Hunt for Red October | US | 1991-01 |
HiTech Software | Commercial |
| The Krion Conquest | US | 1991-01 |
Vic Tokai | Commercial |
| The Untouchables | US | 1991-01 |
Ocean Software | Commercial |
| Wai Wai World 2 - SOS!! Parsley Jou | JP | 1991-01 |
Konami | Commercial |
| Wayne Gretzky Hockey | US | 1991-01 |
Bethesda Softworks | Commercial |
| Zombie Nation | US | 1991-01 |
Meldac | Prototype |
| Cosmos Cop | ES | 1991-01-01 |
Gluk Video | Unlicensed |
| Cosmos Cop | TW | 1991-01-01 |
Gluk Video | Unlicensed |
| Juvei Quest | JP | 1991-01-04 |
Namco | Commercial |
| Bigfoot | EU | 1991-01-24 |
Acclaim Entertainment | Commercial |
| The Adventures of Bayou Billy | EU | 1991-01-24 |
Konami | Commercial |
| Wrath of the Black Manta | EU | 1991-01-24 |
Taito | Commercial |
| Yume Penguin Monogatari | JP | 1991-01-25 |
Konami | Commercial |
| Paperboy | JP | 1991-01-30 |
Mindscape | Commercial |
| Golf Grand Slam | JP | 1991-01-31 |
Atlus | Commercial |
| Adventure Island II | AS | 1991-02 |
| Unlicensed |
| Adventure Island II | US | 1991-02 |
Hudson Soft | Commercial |
| Adventure Island II | US | 1991-02 |
Hudson Soft | Prototype |
| Akagawa Jirou no Yuurei Ressha | JP | 1991-02 |
King Records | Commercial |
| Conan | US | 1991-02 |
Mindscape | Commercial |
| Double Dragon III - The Rosetta Stone | US | 1991-02 |
Technōs Japan | Prototype |
| Double Dragon III - The Sacred Stones | US | 1991-02 |
Acclaim Entertainment | Commercial |
| Famicom Shougi - Ryuuousen | JP | 1991-02 |
I'Max | Commercial |
| Famicom Shougi - Ryuuousen | JP | 1991-02 |
I'Max | Prototype |
| Flying Warriors | US | 1991-02 |
Culture Brain | Commercial |
| Flying Warriors | US | 1991-02 |
Culture Brain | Prototype |
| Galaxy 5000 - Racing in the 51st Century | EU | 1991-02 |
Activision | Commercial |
| Galaxy 5000 - Racing in the 51st Century | US | 1991-02 |
Activision | Commercial |
| Galaxy 5000 - Racing in the 51st Century | US | 1991-02 |
Activision | Prototype |
| Ide Yousuke Meijin no Jissen Mahjong II | JP | 1991-02 |
Capcom | Commercial |
| Ikari III - The Rescue | US | 1991-02 |
SNK | Commercial |
| Isolated Warrior | EU | 1991-02 |
Nintendo | Commercial |
| Isolated Warrior | US | 1991-02 |
Nintendo | Commercial |
| Magician | US | 1991-02 |
Taxan USA Corp | Commercial |
| Magician | US | 1991-02 |
Taxan USA Corp | Prototype |
| Metal Storm | US | 1991-02 |
Irem | Commercial |
| Metal Storm | WORLD | 1991-02 |
Irem | Commercial |
| Niji no Silk Road | JP | 1991-02 |
Victor Entertainment | Commercial |
| Parasol Henbee | JP | 1991-02 |
Epoch | Commercial |
| Princess Tomato in the Salad Kingdom | US | 1991-02 |
Hudson Soft | Commercial |
| Princess Tomato in the Salad Kingdom | US | 1991-02 |
Hudson Soft | Prototype |
| Shentan Kenan | CN | 1991-02 |
King Records | Unlicensed |
| Super Cars | US | 1991-02 |
Magnetic Fields | Commercial |
| The Last Ninja | US | 1991-02 |
Beam Software | Commercial |
| The Simpsons - Bart vs. the Space Mutants | US | 1991-02 |
Acclaim Entertainment | Commercial |
| The Simpsons - Bart vs. the Space Mutants | US | 1991-02 |
Acclaim Entertainment | Prototype |
| The Simpsons - Bart vs. the World | US | 1991-02 |
Acclaim Entertainment | Commercial |
| Touchdown Fever | US | 1991-02 |
SNK | Commercial |
| Championship Bowling | JP | 1991-02-08 |
Romstar | Commercial |
| Dark Lord | JP | 1991-02-08 |
Data East | Commercial |
| Max Warrior - Wakusei Kaigenrei | JP | 1991-02-15 |
Nintendo | Commercial |
| Mini-Putt | JP | 1991-02-15 |
A Wave | Commercial |
| Mini-Putt | US | 1991-02-15 |
A Wave | Prototype |