| Athletic World | EU | 1988-06-15 |
Bandai | Commercial |
| Gumshoe | EU | 1988-06-15 |
Nintendo | Commercial |
| Gun.Smoke | EU | 1988-06-15 |
Capcom | Commercial |
| Blaster Master | WORLD | 1988-06-17 |
Sunsoft | Commercial |
| 1943 - The Battle of Midway | JP | 1988-06-20 |
Capcom | Prototype |
| 1943 - The Battle of Valhalla | JP | 1988-06-20 |
Capcom | Commercial |
| Kyuukyoku Harikiri Stadium | JP | 1988-06-28 |
Taito | Prototype |
| Bases Loaded | US | 1988-07 |
Jaleco | Commercial |
| Bases Loaded | US | 1988-07 |
Jaleco | Prototype |
| Defender II | US | 1988-07 |
HAL Laboratory | Commercial |
| Gauntlet | US | 1988-07 |
Tengen | Commercial |
| Gauntlet | US | 1988-07 |
Tengen | Prototype |
| Gauntlet | US | 1988-07 |
Tengen | Unlicensed |
| Hiryuu no Ken II - Dragon no Tsubasa | JP | 1988-07 |
Culture Brain | Commercial |
| Hitler no Fukkatsu - Top Secret | JP | 1988-07 |
Capcom | Commercial |
| Hitler no Fukkatsu - Top Secret | JP | 1988-07 |
Capcom | Prototype |
| Iron Tank - The Invasion of Normandy | EU | 1988-07 |
SNK | Commercial |
| Iron Tank - The Invasion of Normandy | US | 1988-07 |
SNK | Commercial |
| Iron Tank - The Invasion of Normandy | US | 1988-07 |
SNK | Prototype |
| Ki no Bouken - The Quest of Ki | JP | 1988-07 |
Namco | Commercial |
| Kid Kool | AS | 1988-07 |
| Unlicensed |
| Legendary Wings | US | 1988-07 |
Capcom | Commercial |
| Legendary Wings | US | 1988-07 |
Capcom | Prototype |
| Maison Ikkoku | JP | 1988-07 |
Bothtec | Commercial |
| Nekketsu Koukou Dodgeball-bu | JP | 1988-07 |
Sony Imagesoft | Commercial |
| Salad no Kuni no Tomato Hime | JP | 1988-07 |
Hudson Soft | Commercial |
| The Tale - Elrond no Eiyuu | JP | 1988-07 |
Acclaim Entertainment | Prototype |
| Super Black Onyx | JP | 1988-07-14 |
Bullet-Proof Software | Commercial |
| Densetsu no Kishi - Elrond | JP | 1988-07-15 |
Acclaim Entertainment | Commercial |
| Jarinko Chie - Bakudan Musume no Shiawase Sagashi | JP | 1988-07-15 |
Konami | Commercial |
| Donkey Kong Jr. Math | EU | 1988-07-18 |
Nintendo | Commercial |
| Kakefu-kun no Jump Tengoku - Speed Jigoku | JP | 1988-07-22 |
Vic Tokai | Commercial |
| Super Dodge Ball | WORLD | 1988-07-26 |
CSG Imagesoft | Commercial |
| Great Tank | JP | 1988-07-29 |
SNK | Commercial |
| Super Real Baseball '88 | JP | 1988-07-30 |
Vap | Commercial |
| Dragon Ball - Daimaou Fukkatsu | JP | 1988-08 |
Bandai | Commercial |
| Eggerland - Meikyuu no Fukkatsu | JP | 1988-08 |
HAL Laboratory | Commercial |
| Life Force | TW | 1988-08 |
| Unlicensed |
| Life Force | US | 1988-08 |
Konami | Commercial |
| Mito Koumon - Sekai Manyuu Ki | JP | 1988-08 |
Sunsoft | Commercial |
| Moero!! Pro Yakyuu '88 - Ketteiban | JP | 1988-08 |
Jaleco | Commercial |
| Sangokushi | JP | 1988-08 |
Koei | Commercial |
| Soccer League - Winner's Cup | JP | 1988-08 |
Data East | Commercial |
| Taiyou no Shinden | JP | 1988-08 |
Infocom | Commercial |
| Tatakae!! Rahmen Man - Sakuretsu Choujin 102 Gei | JP | 1988-08 |
Bandai | Commercial |
| World Class Track Meet | US | 1988-08 |
Nintendo | Commercial |
| The Money Game | JP | 1988-08-10 |
Sofel | Commercial |
| Famicom Wars | JP | 1988-08-12 |
Nintendo | Commercial |
| Final Lap | JP | 1988-08-12 |
Namco | Commercial |
| Mad City | JP | 1988-08-12 |
Konami | Commercial |
| Mad City | JP | 1988-08-12 |
Konami | Prototype |
| Hototogisu | JP | 1988-08-19 |
Irem | Commercial |
| Super Pinball | JP | 1988-08-23 |
Coconuts Japan | Commercial |
| Super Pinball | JP | 1988-08-23 |
Coconuts Japan | Prototype |
| Kame no Ongaeshi - Urashima Densetsu | JP | 1988-08-26 |
Hudson Soft | Commercial |
| Super Dyna'mix Badminton | JP | 1988-08-26 |
Vap | Commercial |
| Ys | JP | 1988-08-26 |
Nihon Falcom | Commercial |
| Adventure Island | US | 1988-09 |
Hudson Soft | Commercial |
| Contra | JP | 1988-09 |
Konami | Commercial |
| Contra | JP | 1988-09 |
Konami | Demo |
| Erika to Satoru no Yume Bouken | JP | 1988-09 |
Namco | Commercial |
| Famicom Meijin Sen | JP | 1988-09 |
SNK | Commercial |
| Galaga - Demons of Death | US | 1988-09 |
Bandai | Commercial |
| Golgo 13 - Top Secret Episode | US | 1988-09 |
Vic Tokai | Commercial |
| Jackal | US | 1988-09 |
Konami | Commercial |
| Jeopardy! | US | 1988-09 |
GameTek | Commercial |
| Konamic Sports in Seoul | JP | 1988-09 |
Konami | Commercial |
| Kujaku Ou | JP | 1988-09 |
Pony Canyon | Commercial |
| Lee Trevino's Fighting Golf | US | 1988-09 |
SNK | Commercial |
| Milon's Secret Castle | US | 1988-09 |
Hudson Soft | Commercial |
| Reigen Doushi | JP | 1988-09 |
FCI | Commercial |
| Wheel of Fortune | US | 1988-09 |
GameTek | Commercial |
| Xevious - The Avenger | US | 1988-09 |
Namco | Commercial |
| Xevious - The Avenger | WORLD | 1988-09 |
Bandai | Commercial |
| Maniac Mansion | DE | 1988-09-13 |
Jaleco | Commercial |
| Maniac Mansion | ES | 1988-09-13 |
Jaleco | Commercial |
| Maniac Mansion | EU | 1988-09-13 |
Jaleco | Commercial |
| Maniac Mansion | FR | 1988-09-13 |
Jaleco | Commercial |
| Maniac Mansion | IT | 1988-09-13 |
Jaleco | Commercial |
| Maniac Mansion | JP | 1988-09-13 |
Jaleco | Commercial |
| Maniac Mansion | SE | 1988-09-13 |
Jaleco | Commercial |
| Donald Duck | JP | 1988-09-22 |
Kemco | Commercial |
| Zelda II - The Adventure of Link | EU | 1988-09-26 |
Nintendo | Commercial |
| 8 Eyes | EU | 1988-09-27 |
Taxan USA Corp | Commercial |
| 8 Eyes | JP | 1988-09-27 |
Taxan USA Corp | Commercial |
| 8 Eyes | WORLD | 1988-09-27 |
Taxan USA Corp | Commercial |
| Knight Rider | JP | 1988-09-30 |
Acclaim Entertainment | Commercial |
| Viva! Las Vegas | JP | 1988-09-30 |
HAL Laboratory | Commercial |
| 1943 - The Battle of Midway | US | 1988-10 |
Capcom | Commercial |
| 1943 - The Battle of Midway | US | 1988-10 |
Capcom | Prototype |
| America Daitouryou Senkyo | JP | 1988-10 |
HectorSoft | Commercial |
| Best Play Pro Yakyuu | JP | 1988-10 |
ASCII Corporation | Commercial |
| Donkey Kong Classics | EU | 1988-10 |
Nintendo | Commercial |
| Donkey Kong Classics | US | 1988-10 |
Nintendo | Commercial |
| Genpei Touma Den - Computer Boardgame | JP | 1988-10 |
Namco | Commercial |
| Ghostbusters | US | 1988-10 |
Activision | Commercial |
| Jackal | WORLD | 1988-10 |
Konami | Commercial |
| Joust | US | 1988-10 |
HAL Laboratory | Commercial |
| Mickey Mousecapade | US | 1988-10 |
Capcom | Commercial |
| Millipede | US | 1988-10 |
HAL Laboratory | Commercial |