| Tagin' Dragon | US | 1990 |
Bunch Games | Unlicensed |
| Taro's Quest | US | 1990 |
Jaleco | Prototype |
| The Legend of Robin Hood | US | 1990 |
Arcadia Systems | Prototype |
| The Miracle Piano Teaching System | DE | 1990 |
The Software Toolworks | Commercial |
| The Miracle Piano Teaching System | FR | 1990 |
The Software Toolworks | Commercial |
| The Miracle Piano Teaching System | UK | 1990 |
The Software Toolworks | Commercial |
| Tiles of Fate | US | 1990 |
American Video Entertainment | Unlicensed |
| Twin Eagle | US | 1990 |
American Video Entertainment | Commercial |
| The Chessmaster | AS | 1990-01 |
| Unlicensed |
| The Chessmaster | US | 1990-01 |
HiTech Software | Commercial |
| Top Gun - The Second Mission | US | 1990-01 |
Konami | Commercial |
| Twin Cobra | US | 1990-01 |
Sammy | Commercial |
| Tiger-Heli | EU | 1990-01-17 |
Acclaim Entertainment | Commercial |
| Tank 1990 | CN | 1990-02 |
| Unlicensed |
| To the Earth | EU | 1990-02-23 |
Nintendo | Commercial |
| Target - Renegade | US | 1990-03 |
Taito | Commercial |
| Target - Renegade | WORLD | 1990-03 |
Taito | Commercial |
| Terra Cresta | US | 1990-03 |
Nichibutsu | Commercial |
| Terra Cresta | US | 1990-03 |
Nihon Bussan | Prototype |
| Tecmo World Wrestling | US | 1990-04 |
Tecmo | Commercial |
| Tecmo World Wrestling | US | 1990-04 |
Tecmo | Demo |
| The Escape from Atlantis | US | 1990-05 |
Color Dreams | Unlicensed |
| The Escape from Atlantis | US | 1990-05 |
Color Dreams | Prototype |
| The Last Starfighter | US | 1990-06 |
Mindscape | Commercial |
| The Mafat Conspiracy | US | 1990-06 |
Vic Tokai | Commercial |
| The Adventures of Gilligan's Island | US | 1990-07 |
Bandai | Commercial |
| The Pennant League - Home Run Nighter '90 | JP | 1990-07 |
Data East | Commercial |
| The Bugs Bunny Blowout | EU | 1990-08 |
Kemco | Commercial |
| Total Recall | US | 1990-08 |
Acclaim Entertainment | Commercial |
| Titan | JP | 1990-08-10 |
Sofel | Commercial |
| Titan | WORLD | 1990-08-10 |
Sofel | Commercial |
| Teenage Mutant Hero Turtles | EU | 1990-08-17 |
Konami | Commercial |
| Teenage Mutant Ninja Turtles | AU | 1990-08-17 |
Konami | Commercial |
| Tamura Koushou Mahjong Seminar | JP | 1990-09 |
Pony Canyon | Commercial |
| Tantei Jinguuji Saburou - Toki no Sugiyuku Mama ni | JP | 1990-09 |
Data East | Commercial |
| The Bugs Bunny Birthday Blowout | US | 1990-09 |
Kemco | Commercial |
| Thunderbirds | US | 1990-09 |
Activision | Commercial |
| Time Lord | EU | 1990-09 |
Milton Bradley | Commercial |
| Time Lord | US | 1990-09 |
Milton Bradley | Commercial |
| Totally Rad | WORLD | 1990-09-28 |
Jaleco | Commercial |
| The Immortal | US | 1990-11 |
Electronic Arts | Commercial |
| The Immortal | US | 1990-11 |
Electronic Arts | Demo |
| The Immortal | WORLD | 1990-11 |
Electronic Arts | Commercial |
| The Punisher | AS | 1990-11 |
| Unlicensed |
| The Punisher | US | 1990-11 |
Beam Software | Commercial |
| Tecmo World Wrestling | EU | 1990-11-23 |
Tecmo | Commercial |
| Tecmo Bowl | JP | 1990-11-30 |
Tecmo | Commercial |
| Teenage Mutant Ninja Turtles | JP | 1990-12 |
Konami | Commercial |
| Teenage Mutant Ninja Turtles II - The Arcade Game | AS | 1990-12 |
| Unlicensed |
| Teenage Mutant Ninja Turtles II - The Arcade Game | US | 1990-12 |
Konami | Commercial |
| Teenage Mutant Ninja Turtles II - The Arcade Game | US | 1990-12 |
Konami | Demo |
| The Adventures of Rad Gravity | US | 1990-12 |
Activision | Commercial |
| The Adventures of Rad Gravity | US | 1990-12 |
Activision | Prototype |
| The Adventures of Rad Gravity | WORLD | 1990-12 |
Activision | Commercial |
| The Bard's Tale | JP | 1990-12 |
FCI | Commercial |
| The Bard's Tale | JP | 1990-12 |
FCI | Prototype |
| Thunder & Lightning | US | 1990-12 |
Romstar | Commercial |
| Turtle Ninja II | AS | 1990-12 |
| Unlicensed |
| Tecmo World Cup Soccer | JP | 1990-12-07 |
Tecmo | Commercial |
| Times of Lore | JP | 1990-12-07 |
Toho | Commercial |