| Magic Jewelry | TW | 1990 |
RCM | Unlicensed |
| Magical Mathematics | AS | 1990 |
Sachen | Unlicensed |
| Magical Mathematics | TW | 1990 |
Sachen | Unlicensed |
| Mahjang Companion | JP | 1990 |
Hacker International | Unlicensed |
| Mahjang Companion | TW | 1990 |
Hacker International | Unlicensed |
| Mahjong Samit - Kabukicho Hen | JP | 1990 |
Hacker International | Unlicensed |
| Menace Beach | US | 1990 |
Color Dreams | Unlicensed |
| Millionaire | TW | 1990 |
Sachen | Unlicensed |
| Mindblower Pak | AU | 1990 |
Home Entertainment Suppliers | Unlicensed |
| Mission Cobra | US | 1990 |
Bunch Games | Unlicensed |
| Moon Ranger | US | 1990 |
Bunch Games | Unlicensed |
| Mr. Assy - Momoco & Hanako | AS | 1990 |
Sunsoft | Prototype |
| Metal Arms | JP | 1990-01 |
Dempa Shinbunsha | Unlicensed |
| Mortal Amrs | AS | 1990-02 |
| Unlicensed |
| Mottomo Abunai Deka | JP | 1990-02-06 |
Toei Animation | Commercial |
| Magic Johnson's Fast Break | US | 1990-03 |
Tradewest | Commercial |
| Magic Johnson's Fast Break | US | 1990-03 |
Tradewest | Prototype |
| Mouryou Senki Madara | JP | 1990-03 |
Konami | Commercial |
| Moai-kun | JP | 1990-03-09 |
Konami | Commercial |
| Mashin Eiyuuden Wataru Gaiden | JP | 1990-03-23 |
Hudson Soft | Commercial |
| Mechanized Attack | US | 1990-06 |
SNK | Commercial |
| Meikyuu-jima | JP | 1990-06 |
Nintendo | Commercial |
| Michael Andretti's World GP | US | 1990-06 |
Sammy | Commercial |
| Moero!! Juudou Warriors | JP | 1990-06 |
Jaleco | Commercial |
| Mad Max | US | 1990-07 |
Mindscape | Commercial |
| Might and Magic - Book One - Secret of the Inner Sanctum | JP | 1990-07 |
New World Computing | Commercial |
| Moe Pro! '90 - Kandou Hen | JP | 1990-07 |
Jaleco | Commercial |
| Matendouji | JP | 1990-08 |
Asmik | Commercial |
| M.U.L.E | US | 1990-09 |
Mindscape | Commercial |
| Maniac Mansion | US | 1990-09 |
Jaleco | Commercial |
| Maniac Mansion | US | 1990-09 |
Jaleco | Prototype |
| Mission - Impossible | AS | 1990-09 |
| Unlicensed |
| Mission - Impossible | US | 1990-09 |
Nintendo | Commercial |
| Magic John | JP | 1990-09-28 |
Jaleco | Commercial |
| Mega Man 3 | WORLD | 1990-09-28 |
Capcom | Commercial |
| Mendel Palace | EU | 1990-10 |
Hudson Soft | Commercial |
| Mendel Palace | US | 1990-10 |
Hudson Soft | Commercial |
| Mizushima Shinji no Daikoushien | JP | 1990-10 |
Capcom | Commercial |
| Majaventure - Mahjong Senki | JP | 1990-10-19 |
Tokuma Shoten | Commercial |
| Mega Man 3 | US | 1990-11 |
Capcom | Commercial |
| Mega Man 3 | US | 1990-11 |
Capcom | Prototype |
| Meikyuu no Tatsujin - Daimeiro | JP | 1990-11 |
Epoch | Commercial |
| Muppet Adventure - Chaos at the Carnival | US | 1990-11 |
HiTech Software | Commercial |
| Muppet Adventure - Chaos at the Carnival | US | 1990-11 |
Hi Tech Expressions | Prototype |
| Magical Kid's Doropie | JP | 1990-12 |
Vic Tokai | Commercial |
| Magical Kid's Doropie | JP | 1990-12 |
Vic Tokai | Prototype |
| Metal Flame - Psy Buster | JP | 1990-12 |
Jaleco | Commercial |
| MetalMech - Man & Machine | WORLD | 1990-12 |
Jaleco | Commercial |
| Musashi no Bouken | JP | 1990-12 |
Sigma Enterprises | Commercial |
| Magical Doropie | AS | 1990-12-14 |
| Unlicensed |
| Mega Man 2 | EU | 1990-12-14 |
Capcom | Commercial |