| Sonic Spinball | BR | 1993 |
Sega of America | Prototype |
| Sonic Spinball | EU | 1993 |
Sega of America | Commercial |
| Sonic Spinball | EU | 1993 |
Sega of America | Prototype |
| Sonic Spinball | US | 1993 |
Sega of America | Commercial |
| Sonic Spinball | US | 1993 |
Sega of America | Prototype |
| Sonic The Hedgehog | JP | 1991-12-28 |
Sega of America | Commercial |
| Sonic The Hedgehog | JP | 1991-12-28 |
Sega of America | Prototype |
| Sonic The Hedgehog | US | 1992-02 |
Sega of America | Commercial |
| Sonic The Hedgehog | US | 1992-02 |
Sega of America | Prototype |
| Sonic The Hedgehog | WORLD | 1991-11-18 |
Sega of America | Commercial |
| Sonic The Hedgehog - Triple Trouble | BR | 1994-11 |
Sega Enterprises | Commercial |
| Sonic The Hedgehog - Triple Trouble | BR | 1994-11 |
Sega Enterprises | Prototype |
| Sonic The Hedgehog - Triple Trouble | EU | 1994-11 |
Sega Enterprises | Commercial |
| Sonic The Hedgehog - Triple Trouble | EU | 1994-11 |
Sega Enterprises | Prototype |
| Sonic The Hedgehog - Triple Trouble | US | 1994-11 |
Sega Enterprises | Commercial |
| Sonic The Hedgehog - Triple Trouble | US | 1994-11 |
Sega Enterprises | Prototype |
| Sonic The Hedgehog 2 | US | 1992-12 |
Sega of America | Demo |
| Sonic The Hedgehog 2 | WORLD | 1992-11-21 |
Sega of America | Commercial |
| Soukoban | JP | 1990-12 |
Riverhillsoft | Commercial |
| Space Harrier | WORLD | 1991-11 |
Sega Enterprises | Commercial |
| Space Tonbow | WORLD | |
| Unlicensed |
| Spider-Man | EU | 1992-06 |
Flying Edge | Commercial |
| Spider-Man | US | 1992-06 |
Flying Edge | Commercial |
| Spider-Man - Return of the Sinister Six | EU | 1993 |
Flying Edge | Commercial |
| Spider-Man - Return of the Sinister Six | US | 1993 |
Flying Edge | Commercial |
| Spider-Man - X-Men - Arcade's Revenge | US | 1994-03 |
Flying Edge | Commercial |
| Spider-Man - X-Men - Arcade's Revenge | WORLD | 1994-03 |
Flying Edge | Commercial |
| Spirou | EU | 1996 |
Infogrames | Prototype |
| Sports Illustrated - Championship Football & Baseball | US | 1995 |
Black Pearl Software | Commercial |
| Sports Trivia | US | 1995 |
Sega of America | Commercial |
| Sports Trivia | US | 1995 |
Sega of America | Prototype |
| Sports Trivia - Championship Edition | US | 1995 |
Sega of America | Commercial |
| Sports Trivia - Championship Edition | US | 1995 |
Sega of America | Prototype |
| Star Trek - The Next Generation - The Advanced Holodeck Tutorial | US | 1994 |
Absolute Entertainment | Commercial |
| Star Trek Generations - Beyond the Nexus | US | 1994-12 |
Absolute Entertainment | Commercial |
| Star Wars | EU | 1993-10 |
U.S. Gold | Commercial |
| Star Wars | US | 1993-10 |
U.S. Gold | Commercial |
| Stargate | WORLD | 1994 |
Acclaim Entertainment | Commercial |
| Stinger | WORLD | |
| Unlicensed |
| Street Battle | US | 1993 |
Innovation Tech | Prototype |
| Street Hero | US | 1993 |
Innovation Tech | Prototype |
| Streets of Rage | WORLD | 1992-10-18 |
Sega of America | Commercial |
| Streets of Rage 2 | WORLD | 1993-07 |
Sega of America | Commercial |
| Streets of Rage 2 | WORLD | 1993-07 |
Sega of America | Prototype |
| Striker | EU | 1995 |
Sega Enterprises | Commercial |
| Super Battletank | US | 2001 |
Majesco Entertainment | Commercial |
| Super Columns | EU | 1995-05-26 |
Sega of America | Commercial |
| Super Columns | EU | 1995-05-26 |
Sega of America | Prototype |
| Super Columns | JP | 1995-05-26 |
Sega of America | Commercial |
| Super Columns | US | 1995-06-05 |
Sega of America | Commercial |
| Super Columns | US | 1995-06-05 |
Sega of America | Prototype |
| Super Golf | JP | 1991-04-19 |
Sage's Creation | Commercial |
| Super Golf | US | 1991-04 |
Sage's Creation | Commercial |
| Super Kick Off | EU | 1991 |
U.S. Gold | Commercial |
| Super Momotarou Dentetsu III | JP | 1995-12-15 |
Hudson Soft | Commercial |
| Super Monaco GP | BR | 1990-10-06 |
Sega Enterprises | Commercial |
| Super Monaco GP | EU | 1991 |
Sega Enterprises | Commercial |
| Super Monaco GP | JP | 1990-10-06 |
Sega Enterprises | Commercial |
| Super Monaco GP | KR | 1990-10 |
Sega Enterprises | Commercial |
| Super Monaco GP | US | 1991 |
Sega Enterprises | Commercial |
| Super Off Road | EU | 1992-12-12 |
Virgin | Commercial |
| Super Off Road | EU | 1992-12-12 |
Virgin | Prototype |
| Super Off Road | US | 1993-01 |
Virgin | Commercial |
| Super Off Road | US | 1993-01 |
Virgin | Prototype |
| Super Princess' 2092 - Exodus | WORLD | |
| Unlicensed |
| Super Smash T.V | WORLD | 1992-09 |
Flying Edge | Commercial |
| Super Space Invaders | EU | 1992 |
Domark | Commercial |
| Super Space Invaders | US | 1992 |
Domark | Commercial |
| Super Star Wars - Return of the Jedi | EU | 1995 |
Black Pearl Software | Commercial |
| Super Star Wars - Return of the Jedi | US | 1995 |
Black Pearl Software | Commercial |
| Superman - The Man of Steel | EU | 1993-05 |
Virgin | Commercial |
| Superman - The Man of Steel | EU | 1993-05 |
Virgin | Prototype |
| Surf Ninjas | BR | 1993-08 |
Sega of America | Commercial |
| Surf Ninjas | EU | 1993-08 |
Sega of America | Commercial |
| Surf Ninjas | US | 1993-08 |
Sega of America | Commercial |
| Sushi Nights | WORLD | |
| Unlicensed |
| Svellas Micro | WORLD | |
| Unlicensed |
| Swabby | WORLD | 2016-03 |
| Unlicensed |
| Sylvan Tale | JP | 1995-01-27 |
Sega Enterprises | Commercial |
| T2 - The Arcade Game | EU | 1994-01 |
Arena Entertainment | Commercial |
| T2 - The Arcade Game | JP | 1994-02-25 |
Arena Entertainment | Commercial |
| T2 - The Arcade Game | US | 1993-09 |
Arena Entertainment | Commercial |
| Tails Adventure | WORLD | 1995-09-22 |
Sega Enterprises | Commercial |
| Tails' Skypatrol | JP | 1995-04-28 |
Sega Enterprises | Commercial |
| Taisen Mahjong HaoPai | JP | 1990-11-10 |
Sega Enterprises | Commercial |
| Taisen Mahjong HaoPai 2 | JP | 1993-12-17 |
Sega Enterprises | Commercial |
| Taisen-gata Daisenryaku G | JP | 1991-09-28 |
SystemSoft | Commercial |
| Taito Chase H.Q | JP | 1991-03 |
Taito | Commercial |
| TaleSpin | BR | 1993-03 |
Sega of America | Commercial |
| TaleSpin | EU | 1993-03 |
Sega of America | Commercial |
| TaleSpin | US | 1993-03 |
Sega of America | Commercial |
| Tama & Friends - 3 Choume Kouen Tamalympic | JP | 1995-03-03 |
Sega Enterprises | Commercial |
| Tarot no Yakata | JP | 1991-03 |
Sega Enterprises | Commercial |
| Tarzan - Lord of the Jungle | EU | 1994-11-10 |
GameTek | Commercial |
| Tatakae! Pro Yakyuu Twin League | JP | 1995-07-14 |
Sega Enterprises | Commercial |
| Taz in Escape from Mars | BR | 1994-10 |
Sega of America | Commercial |
| Taz in Escape from Mars | BR | 1994-10 |
Sega of America | Prototype |
| Taz in Escape from Mars | EU | 1994-10 |
Sega of America | Commercial |
| Taz in Escape from Mars | EU | 1994-10 |
Sega of America | Prototype |
| Taz in Escape from Mars | US | 1994-10 |
Sega of America | Commercial |