| SD Gundam - Winner's History | JP | 1995-03-24 |
Bandai | Commercial |
| Samurai Shodown | US | 1994-12 |
Takara | Commercial |
| Samurai Spirits | JP | 1994-12 |
Takara | Commercial |
| Sassou Shounen Eiyuuden - Coca-Cola Kid | JP | 1994-08 |
Sega Enterprises | Commercial |
| Scratch Golf | JP | 1994-03-25 |
Vic Tokai | Commercial |
| Scratch Golf | US | 1994-03 |
Vic Tokai | Commercial |
| Sega Game Pack 4 in 1 | EU | 1992-12 |
Sega Enterprises | Commercial |
| Sega Game Pack 4 in 1 | EU | 1992-12 |
Sega Enterprises | Prototype |
| Sensible Soccer - European Champions | EU | 1993-11 |
Sony Imagesoft | Commercial |
| Shadam Crusader - Harukanaru Oukoku | JP | 1992-09 |
Sega of America | Commercial |
| Shanghai II | JP | 1990-12-27 |
Sunsoft | Commercial |
| Shaq Fu | US | 1995 |
Electronic Arts | Commercial |
| Shikinjou | JP | 1991-04-26 |
Sunsoft | Commercial |
| Shining Force - The Sword of Hajya | EU | 1993-06 |
Sega of America | Commercial |
| Shining Force - The Sword of Hajya | US | 1994-10 |
Sega of America | Commercial |
| Shining Force - The Sword of Hajya | US | 1994-06 |
Sega of America | Prototype |
| Shining Force Gaiden - Ensei, Jashin no Kuni e | JP | 1992-12 |
Sega Enterprises | Commercial |
| Shining Force Gaiden - Final Conflict | JP | 1995-06-30 |
Sega Enterprises | Commercial |
| Shining Force Gaiden II - Jashin no Kakusei | JP | 1993-06 |
Sega of America | Commercial |
| Shinobi | WORLD | 1991-04 |
Sega of America | Commercial |
| Shinobi II - The Silent Fury | WORLD | 1992-12 |
Sega of America | Commercial |
| Side Pocket | US | 1994 |
Data East USA | Commercial |
| Skweek | JP | 1991-04 |
Sega Enterprises | Commercial |
| Slider | EU | 1991-04 |
Sega Enterprises | Commercial |
| Slider | US | 1991-04 |
Sega Enterprises | Commercial |
| Snake GBGG | WORLD | |
| Unlicensed |
| Snepzhen Solitaire | WORLD | 2022-11 |
| Unlicensed |
| Solitaire FunPak | US | 1994 |
Interplay | Commercial |
| Solitaire Poker | EU | 1991-05 |
Sega | Commercial |
| Solitaire Poker | US | 1991-05 |
Sega | Commercial |
| Sonic & Tails | JP | 1993-11 |
Sega of America | Commercial |
| Sonic & Tails | JP | 1993-11 |
Sega of America | Demo |
| Sonic & Tails 2 | JP | 1994-11 |
Sega Enterprises | Commercial |
| Sonic Blast | WORLD | 1996-11 |
Sega of America | Commercial |
| Sonic Blast | WORLD | 1996-11 |
Sega of America | Prototype |
| Sonic Chaos | BR | 1993-11 |
Sega of America | Commercial |
| Sonic Chaos | BR | 1993-11 |
Sega of America | Prototype |
| Sonic Chaos | EU | 1993-11 |
Sega of America | Commercial |
| Sonic Chaos | EU | 1993-11 |
Sega of America | Prototype |
| Sonic Chaos | US | 1993-11 |
Sega of America | Commercial |
| Sonic Chaos | US | 1993-11 |
Sega of America | Prototype |
| Sonic Drift | JP | 1994-03-18 |
Sega Enterprises | Commercial |
| Sonic Drift | JP | 1994-03-18 |
Sega Enterprises | Demo |
| Sonic Drift 2 | WORLD | 1995-03-17 |
Sega Enterprises | Commercial |
| Sonic Labyrinth | WORLD | 1995-11 |
Sega of America | Commercial |
| Sonic Spinball | BR | 1993 |
Sega of America | Commercial |
| Sonic Spinball | BR | 1993 |
Sega of America | Prototype |
| Sonic Spinball | EU | 1993 |
Sega of America | Commercial |
| Sonic Spinball | EU | 1993 |
Sega of America | Prototype |
| Sonic Spinball | US | 1993 |
Sega of America | Commercial |
| Sonic Spinball | US | 1993 |
Sega of America | Prototype |
| Sonic The Hedgehog | JP | 1991-12-28 |
Sega of America | Commercial |
| Sonic The Hedgehog | JP | 1991-12-28 |
Sega of America | Prototype |
| Sonic The Hedgehog | US | 1992-02 |
Sega of America | Commercial |
| Sonic The Hedgehog | US | 1992-02 |
Sega of America | Prototype |
| Sonic The Hedgehog | WORLD | 1991-11-18 |
Sega of America | Commercial |
| Sonic The Hedgehog - Triple Trouble | BR | 1994-11 |
Sega Enterprises | Commercial |
| Sonic The Hedgehog - Triple Trouble | BR | 1994-11 |
Sega Enterprises | Prototype |
| Sonic The Hedgehog - Triple Trouble | EU | 1994-11 |
Sega Enterprises | Commercial |
| Sonic The Hedgehog - Triple Trouble | EU | 1994-11 |
Sega Enterprises | Prototype |
| Sonic The Hedgehog - Triple Trouble | US | 1994-11 |
Sega Enterprises | Commercial |
| Sonic The Hedgehog - Triple Trouble | US | 1994-11 |
Sega Enterprises | Prototype |
| Sonic The Hedgehog 2 | US | 1992-12 |
Sega of America | Demo |
| Sonic The Hedgehog 2 | WORLD | 1992-11-21 |
Sega of America | Commercial |
| Soukoban | JP | 1990-12 |
Riverhillsoft | Commercial |
| Space Harrier | WORLD | 1991-11 |
Sega Enterprises | Commercial |
| Space Tonbow | WORLD | |
| Unlicensed |
| Spider-Man | EU | 1992-06 |
Flying Edge | Commercial |
| Spider-Man | US | 1992-06 |
Flying Edge | Commercial |
| Spider-Man - Return of the Sinister Six | EU | 1993 |
Flying Edge | Commercial |
| Spider-Man - Return of the Sinister Six | US | 1993 |
Flying Edge | Commercial |
| Spider-Man - X-Men - Arcade's Revenge | US | 1994-03 |
Flying Edge | Commercial |
| Spider-Man - X-Men - Arcade's Revenge | WORLD | 1994-03 |
Flying Edge | Commercial |
| Spirou | EU | 1996 |
Infogrames | Prototype |
| Sports Illustrated - Championship Football & Baseball | US | 1995 |
Black Pearl Software | Commercial |
| Sports Trivia | US | 1995 |
Sega of America | Commercial |
| Sports Trivia | US | 1995 |
Sega of America | Prototype |
| Sports Trivia - Championship Edition | US | 1995 |
Sega of America | Commercial |
| Sports Trivia - Championship Edition | US | 1995 |
Sega of America | Prototype |
| Star Trek - The Next Generation - The Advanced Holodeck Tutorial | US | 1994 |
Absolute Entertainment | Commercial |
| Star Trek Generations - Beyond the Nexus | US | 1994-12 |
Absolute Entertainment | Commercial |
| Star Wars | EU | 1993-10 |
U.S. Gold | Commercial |
| Star Wars | US | 1993-10 |
U.S. Gold | Commercial |
| Stargate | WORLD | 1994 |
Acclaim Entertainment | Commercial |
| Stinger | WORLD | |
| Unlicensed |
| Street Battle | US | 1993 |
Innovation Tech | Prototype |
| Street Hero | US | 1993 |
Innovation Tech | Prototype |
| Streets of Rage | WORLD | 1992-10-18 |
Sega of America | Commercial |
| Streets of Rage 2 | WORLD | 1993-07 |
Sega of America | Commercial |
| Streets of Rage 2 | WORLD | 1993-07 |
Sega of America | Prototype |
| Striker | EU | 1995 |
Sega Enterprises | Commercial |
| Super Battletank | US | 2001 |
Majesco Entertainment | Commercial |
| Super Columns | EU | 1995-05-26 |
Sega of America | Commercial |
| Super Columns | EU | 1995-05-26 |
Sega of America | Prototype |
| Super Columns | JP | 1995-05-26 |
Sega of America | Commercial |
| Super Columns | US | 1995-06-05 |
Sega of America | Commercial |
| Super Columns | US | 1995-06-05 |
Sega of America | Prototype |
| Super Golf | JP | 1991-04-19 |
Sage's Creation | Commercial |
| Super Golf | US | 1991-04 |
Sage's Creation | Commercial |
| Super Kick Off | EU | 1991 |
U.S. Gold | Commercial |