| Suicide Run | WORLD | |
| Unlicensed |
| Super 16 in 1 | TW | |
Sachen | Unlicensed |
| Super 21 in 1 - New GB Rumble | TW | |
| Unlicensed |
| Super 6 in 1 | TW | |
Sachen | Unlicensed |
| Super Black Bass - Real Fight | JP | 1999-12 |
Starfish | Commercial |
| Super Black Bass Pocket 3 | JP | 1998-11 |
American Softworks | Commercial |
| Super Bombliss DX | JP | 1999-12 |
Bullet-Proof Software | Commercial |
| Super Breakout | EU | 1998-12 |
Majesco Entertainment | Commercial |
| Super Breakout | US | 1998-12 |
Majesco Entertainment | Commercial |
| Super Breakout | WORLD | 1998-12 |
Majesco Entertainment | Commercial |
| Super Bunny Mission | WORLD | |
| Unlicensed |
| Super Chinese Fighter EX | JP | 1999-12 |
Culture Brain | Commercial |
| Super Color 26-in-1 | TW | |
| Unlicensed |
| Super Dassalo Land | WORLD | 2024-08 |
GumpyFunction | Unlicensed |
| Super Doll Licca-chan - Kisekae Daisakusen | JP | 2000-10 |
Vial One | Commercial |
| Super Donkey Kong 5 | TW | |
| Unlicensed |
| Super Fighters 99 | TW | |
V.Fame | Unlicensed |
| Super Fighters S | TW | |
| Unlicensed |
| Super Gals! Kotobuki Ran | JP | 2001-07 |
Konami | Commercial |
| Super Gals! Kotobuki Ran 2 - Miracle Getting | JP | 2002-02 |
Konami | Commercial |
| Super Gran | WORLD | |
| Unlicensed |
| Super Impostor Bros | WORLD | 2021-03 |
Newgrounds.com | Unlicensed |
| Super Jacked Up Tomato Face Johnson | WORLD | 2022-05 |
GumpyFunction | Unlicensed |
| Super JetPak DX | WORLD | 2020 |
Pocketpixel Design | Unlicensed |
| Super Mario Bros Mini | WORLD | 2024-11-20 |
Mico27 | Unlicensed |
| Super Mario Bros. Deluxe | EU | 1999-07 |
Nintendo | Commercial |
| Super Mario Bros. Deluxe | JP | 2000-03 |
Nintendo | Commercial |
| Super Mario Bros. Deluxe | US | 1999-07 |
Nintendo | Commercial |
| Super Mario Special 3 | TW | 2000 |
| Unlicensed |
| Super Marrio Sunshine | TW | |
| Unlicensed |
| Super Me-Mail GB - Me-Mail Bear no Happy Mail Town | JP | 2000-12 |
Tomy | Commercial |
| Super Real Fishing | JP | 1999-10 |
Bottom Up Interactive | Commercial |
| Super Robot Pinball | JP | 2001-02 |
Media Factory | Commercial |
| Super Robot Taisen - Link Battler | JP | 1999-10 |
Banpresto | Commercial |
| Supercross Freestyle | EU | 2000-01 |
Infogrames Europe | Commercial |
| Superman - Battle for Metropolis | EU | |
| Prototype |
| Supermarket Spree DX | WORLD | 2023-12 |
| Unlicensed |
| Supershot Golf Robot | US | 1999-07 |
Digital Kids | Prototype |
| Supreme Snowboarding | EU | 1999-01 |
Infogrames | Commercial |
| Survival Kids | US | 1999-10 |
Konami | Commercial |
| Survival Kids - Kotou no Boukensha | JP | 1999-06 |
Konami | Commercial |
| Survival Kids 2 - Dasshutsu!! Futago-jima! | JP | 2000-07 |
Konami | Prototype |
| Survival Kids 2 - Dasshutsu!! Futago-jima! | JP | 2000-07 |
Konami | Commercial |
| Suske en Wiske - De Tijdtemmers ~ Bob et Bobette - Les Dompteurs du Temps | EU | |
Infogrames | Prototype |
| Sutte Hakkun GB | JP | |
| Prototype |
| Suzuki Alstare Extreme Racing | EU | 1999-11 |
Ubisoft | Commercial |
| Suzuki Alstare Extreme Racing | US | 1999-01 |
Ubisoft | Prototype |
| Sweet Ange | JP | 1999-12 |
Koei | Commercial |
| Swing | DE | 2000-10 |
Software 2000 | Commercial |
| Swing | EU | 2000-10 |
Software 2000 | Prototype |
| Swordbird Song - The Iron Owl Tower | WORLD | 2022 |
Felipe Reinicke | Unlicensed |
| Swordsman on the Eternal Journey | WORLD | 2024-04 |
Circle Yousu ga Okashii | Unlicensed |
| Sylvanian Families - Otogi no Kuni no Pendant | JP | 1999-10 |
Epoch | Commercial |
| Sylvanian Families 2 - Irozuku Mori no Fantasy | JP | 2000-12 |
Epoch | Commercial |
| Sylvanian Families 2 - Irozuku Mori no Fantasy | JP | 2000-12-22 |
Epoch | Prototype |
| Sylvanian Families 3 - Hoshi Furu Yoru no Sunadokei | JP | 2001-12 |
Epoch | Commercial |
| Sylvanian Melodies - Mori no Nakama to Odori Masho! | JP | 2000-03 |
Epoch | Commercial |
| Sylvester & Tweety - Breakfast on the Run | EU | 1998-12 |
Infogrames | Commercial |