| Zagan Warrior | WORLD | |
| Unlicensed |
| Zap'em | WORLD | |
| Unlicensed |
| Zebco Fishing! | US | 1999-09 |
Vatical Entertainment | Commercial |
| Zelda no Densetsu - Fushigi no Kinomi - Daichi no Shou | JP | 2001-02 |
Nintendo | Commercial |
| Zelda no Densetsu - Fushigi no Kinomi - Jikuu no Shou | JP | 2001-02 |
Nintendo | Commercial |
| Zelda no Densetsu - Yume o Miru Shima DX | JP | 1998-12-12 |
Nintendo | Prototype |
| Zelda no Densetsu - Yume o Miru Shima DX | JP | 1998-12 |
Nintendo | Commercial |
| Zelda's Adventure | WORLD | |
| Unlicensed |
| Zen-Nihon Shounen Soccer Taikai - Mezase Nihon Ichi! | JP | 2001-09 |
Success | Commercial |
| Zhen Sanguo Wushuang 2 - Shin Sangokumusou | TW | 1999-01 |
Nintendo | Unlicensed |
| Zhihuan Wang - Shoubu Qu | TW | |
| Unlicensed |
| Zhihuan Wang 2 | CN | |
| Unlicensed |
| Zhizhu Xia III - Dianying Ban | TW | |
| Unlicensed |
| Zhong Zhuang Ji Bing | CN | |
| Unlicensed |
| Zidane - Football Generation | EU | 2002-06 |
Aqua Pacific | Commercial |
| Zidane - Football Generation | EU | 2002-06 |
Aqua Pacific | Prototype |
| Zippy The Pinecone | WORLD | 2024-09 |
8 Divided By Zero | Unlicensed |
| Zoboomafoo - Playtime in Zobooland | US | 2001-10 |
Encore Software | Commercial |
| Zodiac | WORLD | 2022-09 |
Rajcsányi László | Unlicensed |
| Zoids - Jashin Fukkatsu! Genobreaker Hen | JP | 2000-08 |
Tomy | Commercial |
| Zoids - Shirogane no Juukishin Liger Zero | JP | 2001-06 |
Tomy | Commercial |
| Zok Zok Heroes | JP | 2000-08 |
KAZe | Commercial |
| Zone Control | WORLD | |
| Unlicensed |
| Zook Z | US | 1998 |
Vast Fame | Unlicensed |
| Zork + Harris | WORLD | |
| Prototype |