| Jingorou | JP | 1988 |
I2 (Aitsu) | Unlicensed |
| Lipstick #1 - Lolita Hen | JP | 1988 |
Hacker International | Unlicensed |
| Lipstick #2 - Joshi Gakusei Hen | JP | 1988 |
Hacker International | Unlicensed |
| Lipstick #3 - OL Hen | JP | 1988 |
Hacker International | Unlicensed |
| Lipstick #4 - Hakui no Tenshi Hen | JP | 1988 |
Hacker International | Unlicensed |
| Lipstick #5 - Stewardess Hen | JP | 1988 |
Hacker International | Unlicensed |
| Zatsugaku Olympic Quiz - Watanabe Wataru Hen | JP | 1988 |
Phoenix Games | Unlicensed |
| Zatsugaku Olympic Quiz Part II | JP | 1988 |
Phoenix Games | Unlicensed |
| Gun.Smoke | JP | 1988-01 |
Capcom | Commercial |
| Ice Hockey | JP | 1988-01 |
Nintendo | Commercial |
| SD Gundam World - Gachapon Senshi - Scramble Wars | JP | 1988-01 |
Bandai Namco | Commercial |
| SD Gundam World - Gachapon Senshi - Scramble Wars - Map Collection | JP | 1988-01 |
Bandai Namco | Commercial |
| Exciting Soccer - Konami Cup | JP | 1988-02 |
Konami | Commercial |
| Fire Bam | JP | 1988-02 |
HAL Laboratory | Commercial |
| Replicart | JP | 1988-02 |
Taito | Commercial |
| Aspic - Majaou no Noroi | JP | 1988-03 |
Bothtec | Commercial |
| Druid - Kyoufu no Tobira | JP | 1988-03 |
Jaleco | Commercial |
| Druid - Kyoufu no Tobira | JP | 1988-03 |
Jaleco | Prototype |
| Nazoler Land - Daisangou | JP | 1988-03 |
Sunsoft | Commercial |
| Neunzehn - 19 | JP | 1988-03 |
Soft Pro International | Commercial |
| Omoikkiri Tanteidan HaadoGumi - Matenrou no Chousenjou | JP | 1988-03 |
Bandai | Commercial |
| TwinBee | JP | 1988-03 |
Konami | Commercial |
| Wardner no Mori | JP | 1988-03 |
Taito | Commercial |
| Bio Miracle Bokutte Upa | JP | 1988-04 |
Konami | Commercial |
| Donkey Kong | JP | 1988-04 |
Nintendo | Commercial |
| Famicom Grand Prix II - 3D Hot Rally | JP | 1988-04 |
Nintendo | Commercial |
| Famicom Tantei Club - Kieta Koukeisha - Zenpen | JP | 1988-04 |
Nintendo | Commercial |
| Fuuun Shourin Ken - Ankoku no Maou | JP | 1988-04 |
Jaleco | Commercial |
| Goonies | JP | 1988-04 |
Konami | Commercial |
| Kamen Rider Black - Taiketsu Shadow Moon | JP | 1988-04 |
Bandai Namco | Commercial |
| Final Command - Akai Yousai | JP | 1988-05 |
Konami | Commercial |
| Bishoujo Mahjong Club | JP | 1988-06 |
Mimi Pro | Unlicensed |
| Famicom Tantei Club - Kieta Koukeisha - Kouhen | JP | 1988-06 |
Nintendo | Commercial |
| Fire Rock | JP | 1988-06 |
Use | Commercial |
| Risa no Yousei Densetsu | JP | 1988-06 |
Konami | Commercial |
| Donkey Kong Jr | JP | 1988-07 |
Nintendo | Commercial |
| Karate Champ | JP | 1988-07 |
Data East | Commercial |
| Konamic Ice Hockey | JP | 1988-07 |
Konami | Commercial |
| Moonball Magic | JP | 1988-07 |
Disk Original Group (DOG) | Commercial |
| Radical Bomber!! Jirai-kun | JP | 1988-07 |
Jaleco | Commercial |
| Tooyama no Kinsan Space Chou - Mr. Gold | JP | 1988-07 |
Toei Animation | Commercial |
| Bakutoushi Patton-kun | JP | 1988-08 |
Soft Pro International | Commercial |
| Big Challenge! Juudou Senshuken | JP | 1988-08 |
Jaleco | Commercial |
| Konamic Tennis | JP | 1988-08 |
Konami | Commercial |
| Konamic Tennis | JP | 1988-08 |
Konami | Prototype |
| Silviana - Ai Ippai no Little Angel | JP | 1988-08 |
Pack-In-Video | Commercial |
| The Money Game | JP | 1988-08 |
Sofel | Prototype |
| Aki to Tsukasa no Fushigi no Kabe | JP | 1988-09 |
New System House Oh! | Unlicensed |
| Bishoujo Sexy Derby | JP | 1988-09 |
Hacker International | Unlicensed |
| Bishoujo Sexy Puzzle | JP | 1988-09 |
Super Pig | Unlicensed |
| Bishoujo Sexy Slot | JP | 1988-09 |
Hacker International | Unlicensed |
| BurgerTime | JP | 1988-09 |
Data East | Commercial |
| Kick and Run | JP | 1988-09 |
Taito | Commercial |
| Matou no Houkai - The Hero of Babel | JP | 1988-09 |
Pony Canyon | Commercial |
| Big Challenge! Dogfight Spirit | JP | 1988-10 |
Jaleco | Commercial |
| Bishoujo Shashinkan - Studio Cut | JP | 1988-10 |
Phoenix Games | Unlicensed |
| Dandy - Zeuon no Fukkatsu | JP | 1988-10 |
Pony Canyon | Commercial |
| Egger Land - Souzou e no Tabidachi | JP | 1988-10 |
HAL Laboratory | Prototype |
| Egger Land - Souzou e no Tabidachi | JP | 1988-10 |
HAL Laboratory | Commercial |
| Pachicom | JP | 1988-10 |
Toshiba EMI | Commercial |
| Ultraman Club - Chikyuu Dakkan Sakusen | JP | 1988-10 |
Bandai Namco | Commercial |
| Yuu Maze | JP | 1988-10 |
Taito | Commercial |
| Bishoujo Shashinkan - Moving School | JP | 1988-11 |
Phoenix Games | Unlicensed |
| German Tanteidan MarinGumi - Maruhi Jigomar Sousa File | JP | 1988-11 |
Bandai Namco | Commercial |
| Gyruss | JP | 1988-11 |
Konami | Commercial |
| Gyruss | JP | 1988-11 |
Konami | Prototype |
| Ice Climber | JP | 1988-11 |
Nintendo | Commercial |
| Pachinko Grand Prix | JP | 1988-11 |
Data East | Commercial |
| Samurai Sword | JP | 1988-11 |
Capcom | Commercial |
| Kaettekita Mario Bros | JP | 1988-11-30 |
Nintendo | Commercial |
| Akuu Senki Raijin | JP | 1988-12 |
Disk Original Group (DOG) | Prototype |
| Akuu Senki Raijin | JP | 1988-12 |
Disk Original Group (DOG) | Commercial |
| Nankin no Adventure | JP | 1988-12 |
Sunsoft | Commercial |
| Tantei Jinguuji Saburou - Kiken na Futari - Zenpen | JP | 1988-12 |
Data East | Commercial |
| Tarot Uranai | JP | 1988-12 |
Scorpion Soft | Commercial |
| Vs. Excitebike | JP | 1988-12 |
Nintendo | Commercial |
| Vs. Excitebike | US | 1988-12-09 |
Nintendo | Commercial |