| Doom 64 | 1997 | n64 |
| Doom 64 | 2020 | ps4, switch |
| Doom 64 | 2020 | xboxone |
| Doom Classic Complete | 2012 | ps3 |
| Doom Eternal | 2020 | ps4, switch, xboxone |
| Doom II | 2019 | ps4, switch |
| Doom II | 2019 | xboxone |
| Doom II - Hell on Earth | 2010 | xbox360 |
| The Double Dynamites | 1989 | arcade |
| Double Hawk | 1990 | sms |
| Double Strike - Aerial Attack Force | 1990 | nes |
| Double Wings | 1993 | arcade |
| Down Load | 1990 | pcengine |
| Down Load 2 | 1991 | pcengine |
| Downwell | 2016 | ps4, vita |
| Dr. Toppel's Adventure | 1987 | arcade |
| Dr. Toppel's Tankentai | 1987 | arcade |
| Draco | 1981 | arcade |
| Dracula - Undead Awakening | 2010 | psp, wii |
| Dragon Blaze | 2006 | ps2, switch |
| Dragon Blaze | 2022 | ps4 |
| Dragon Blaze | 2000 | arcade |
| Dragon Breed | 1989 | arcade |
| Dragon Chronicles | 2002 | arcade |
| Dragon Defender | 1983 | a2600 |
| Dragon Drive - D-Masters Shot | 2003 | gc |
| Dragon Gun | 1992 | arcade |
| Dragon Rage | 2001 | ps2 |
| Dragon Saber | 1990 | arcade, pcengine, wii |
| Dragon Spirit | 1987 | arcade, pcengine |
| Dragon Spirit | 2007 | wii |
| Dragon Spirit - Aratanaru Densetsu | 1989 | nes |
| Dragon Spirit - The New Legend | 1989 | nes |
| Drake of the 99 Dragons | 2003 | xbox |
| Drakton | 1984 | arcade |
| Dream Hunting | 2002 | arcade |
| Dream Trigger 3D | 2011 | 3ds |
| Driv3r | 2004 | gba, ps2, xbox |
| Driver's Eyes | 1992 | arcade |
| Driving Simulator | 2007 | arcade |
| Drop Zone - Under Fire | 2012 | wii |
| Dropzone | 1993 | gb |
| Dropzone | 1999 | gbc |
| Dropzone | 1992 | nes |
| Drunk as I Like 2 - Drunk... Again | 2024 | genesis |
| Dual Assault | 1984 | arcade |
| Duck | 2024 | gb |
| Duck Dynasty | 2014 | xboxone |
| Duke Nukem | 1997 | ps1 |
| Duke Nukem - Critical Mass | 2011 | nds |
| Duke Nukem - Total Meltdown | 1997 | genesis, ps1, saturn |
| Duke Nukem - Zero Hour | 1999 | n64 |
| Duke Nukem 3D | 1997 | gamecom |
| Duke Nukem 3D | 2008 | xbox360 |
| Duke Nukem 3D - Megaton Edition | 2015 | ps3, vita |
| Duke Nukem 3D: 20th Anniversary World Tour | 2016 | ps4, switch, xboxone |
| Duke Nukem 64 | 1997 | n64 |
| Duke Nukem Advance | 2002 | gba |
| Duke Nukem Forever | 2011 | ps3, xbox360 |
| Dungeddon | 2023 | lynx |
| Dusk | 2021 | switch |
| Dust 514 | 2013 | ps3 |
| Dux | 2009 | dreamcast |
| Dux Version 1.5 | 2009 | dreamcast |
| Dyger | 1989 | arcade |
| E.D.F.: Earth Defense Force | 1991 | arcade |
| E.I. - Exa Innova | | sms |
| E.X. Troopers | 2012 | 3ds, ps3 |
| ESP Ra.De | 1998 | arcade |
| ESP Ra.De. - A.D.2018 Tokyo | 1998 | arcade |
| ESP Ra.De. Psi | 2019 | ps4, switch |
| Eagle | 1980 | arcade |
| Eagles 5 | 1990 | sms |
| Earth Atlantis | 2017 | ps4, switch, xboxone |
| Earth Defender | 1992 | svision |
| Earth Defense | 1995 | genesis |
| Earth Defense Force | 1992 | snes |
| Earth Defense Force - Insect Armageddon | 2011 | ps3, xbox360 |
| Earth Defense Force 2 - Invaders From Planet Space | 2015 | vita |
| Earth Defense Force 2017 | 2007 | switch, xbox360 |
| Earth Defense Force 2017 Portable | 2013 | vita |
| Earth Defense Force 2025 | 2014 | ps3, xbox360 |
| Earth Defense Force 2: Invaders from Planet Space | 2021 | switch |
| Earth Defense Force 4.1 | 2015 | ps4 |
| Earth Defense Force 4.1: The Shadow of New Despair | 2022 | switch |
| Earth Defense Force 5 | 2017 | ps4 |
| Earth Defense Force 6 | 2022 | ps4 |
| Earth Defense Force: Iron Rain | 2019 | ps4 |
| Earth Defense Force: World Brothers | 2020 | ps4, switch |
| The Earth Dies Screaming | 1983 | a2600 |
| EarthStation-I | 1987 | arcade |
| Earthfall | 2018 | ps4 |
| Earthfall | 2018 | xboxone |
| Earthfall: Alien Horde | 2019 | switch |
| Eat Lead - The Return of Matt Hazard | 2009 | ps3, xbox360 |
| Ecks V Sever | 2001 | gba |
| Ecks vs. Sever II - Ballistic | 2002 | gba |
| Eco Fighters | 1993 | arcade |
| Eco Shooter - Plant 530 | 2009 | wii |
| Eduardo the Samurai Toaster | 2009 | wii |