| MX5000 | 1987 | arcade |
| Mach-9 | 1984 | arcade |
| Macross 7 - Ginga no Heart o Furuwasero!! | 2000 | gbc |
| Macross II | 1993 | arcade |
| Macross Plus | 1996 | arcade |
| Maerchen Adventure Cotton 100% | 1994 | snes |
| Mag Max | 1985 | arcade |
| Magic Carpet 1001 | 1992 | nes |
| Magic Girl | 2015 | genesis |
| Magical Chase | 1991 | pcengine |
| Magical Chase GB - Minarai Mahoutsukai Kenja no Tani e | 2000 | gbc |
| Magical Taruruuto-kun | 1991 | gg |
| Magical Twin Bee | 1995 | arcade |
| Magmax | 1986 | nes, wiiu |
| Mahou Daisakusen | 1993 | arcade |
| Mahou Keibitai Gun Hohki | 1992 | arcade |
| Makyou Senshi | 1987 | arcade |
| Malzak | | arcade |
| Malzak II | | arcade |
| Mamorukun Curse! | 2008 | arcade, ps3, xbox360 |
| Marine Boy | 1982 | arcade |
| Mariner | 1981 | arcade |
| Markham | 1983 | arcade |
| Mars | 1981 | arcade |
| Mars Matrix | 2000 | dreamcast |
| Mars Matrix: Hyper Solid Shooting | 2000 | arcade |
| Mars: Chaos Menace | 2019 | xboxone |
| Master of Weapon | 1989 | arcade, genesis |
| Math Patrol - The Kleptoid Threat | 2007 | gba |
| Max Warrior - Wakusei Kaigenrei | 1991 | nes |
| Mayday | 1980 | arcade |
| Mazinger Z | 1994 | arcade |
| Mega Blast | 1989 | arcade |
| Mega Force | 1984 | arcade |
| Mega Phoenix | 1991 | arcade |
| Mega SWIV | 1995 | genesis |
| Mercenary Force | 1990 | gb |
| Mercenary Kings - Reloaded Edition | 2018 | vita |
| Meta Fox | 1989 | arcade |
| Metal Black | 1991 | arcade |
| Metal Fighter | 1989 | nes |
| Metal Fighter Mu | 1989 | nes |
| Metal Freezer | 1989 | arcade |
| Metal Hawk | 1988 | arcade |
| Metal Slug | 2007 | ps2, ps3, psp, wii |
| Metal Soldier Isaac II | 1985 | arcade |
| Metal Stoker | 1991 | pcengine |
| Meteor Defense | 1983 | a2600 |
| Microcosm | 1993 | 3do, cd32, segacd |
| Mighty Monkey | 1982 | arcade |
| Mirax | 1985 | arcade |
| Miss Kobayashi's Dragon Maid: Sakuretsu! Chorogon Breath | 2022 | ps4, switch |
| Missile Command | 1980 | a2600, a5200, arcade, gbc |
| Missile War ~ Astro War ~ Astrowar | | a2600 |
| Mission 660 | 1986 | arcade |
| Mission Cobra | 1990 | nes |
| Mission Craft | 2000 | arcade |
| Mission Survive | 1983 | a2600 |
| Moero TwinBee - Cinnamon Hakase o Sukue! | 1993 | nes |
| Moero TwinBee - Cinnamon Hakase wo Sukue! | 1986 | fds |
| Monster Madness - Battle for Suburbia | 2007 | xbox360 |
| Monster Shooter | 2012 | 3ds |
| Moon Shuttle | 1981 | arcade |
| Moonwar | 1981 | arcade |
| Mr. HELI no Daibouken | 1987 | arcade |
| Mr. Heli no Daibouken | 1989 | pcengine |
| Muchi Muchi Pork! | 2007 | arcade |
| Musha Aleste | 1990 | genesis |
| Mushihime-Sama | 2004 | arcade, ps2, switch |
| Mushihime-Sama Futari Black Label | 2007 | arcade |
| Mushihime-Sama Futari Black Label - Another Ver | 2007 | arcade |
| Mushihime-Sama Futari Ver 1.0 | 2006 | arcade |
| Mushihime-Sama Futari Ver 1.5 | 2006 | arcade |
| My Friend Pedro | 2019 | ps4, switch, xboxone |
| Mystic Midway - Rest in Pieces | 1992 | cdi |
| Mystic Riders | 1992 | arcade |
| Nano Assault | 2011 | 3ds |
| Nano Assault Neo X | 2014 | ps4 |
| Nanostray | 2005 | nds |
| Nanostray 2 | 2008 | nds |
| Narc | 2005 | ps2, xbox |
| Natsuki Chronicles | 2019 | ps4, xboxone |
| Nebulas Ray | 1994 | arcade |
| Nemesis | 1990 | gb |
| Nemesis | 1987 | sms |
| Nemesis 2 | 1987 | sms |
| Nemesis II | 1991 | gb |
| Nemesis II - The Return of the Hero | 1992 | gb |
| Neo Geo Heroes - Ultimate Shooting | 2010 | psp |
| Neo XYX | 2014 | dreamcast |
| NeoGeo Heroes - Ultimate Shooting | 2010 | psp |
| New Century | 1981 | arcade |
| Nex Machina | 2017 | ps4 |
| Next Century | 1981 | arcade |
| The Next Space | 1989 | arcade |
| Night Star | 1983 | arcade |
| Night Striker | 1989 | arcade |
| Ninja Commando | 1992 | arcade, neogeo |
| Ninja Emaki | 1986 | arcade |
| Nostradamus | 1993 | arcade |