| The Dalmatians | 2000 | ps1 |
| Dalmatians 2 | 2003 | ps1 |
| Dalmatians 3 | 2006 | ps2 |
| Dancing Eyes | 1996 | arcade |
| Dandy Dungeon: Legend of Brave Yamada | 2019 | switch |
| Dangerous Demolition | 2020 | gg |
| Darq: Complete Edition | 2020 | ps4, switch, xboxone |
| Das Junior Wort-Quiz | 2008 | nds |
| DeJig - Aqua World | 1997 | saturn |
| DeJig - Lassen - Art Collection | 1997 | saturn |
| DeJig - McKnight - Art Collection | 1997 | saturn |
| DeJig - Tin Toy | 1997 | saturn |
| Death Squared | 2017 | ps4, switch, xboxone |
| Debtor | 2020 | genesis |
| Decay | 2019 | xboxone |
| Decay: The Mare | 2017 | xboxone |
| Defend your Crypt | 2016 | wiiu |
| Deflektor | 2003 | gba |
| Deflektor | 2019 | genesis |
| Deleveled | 2020 | ps4 |
| Delta Warp | 2000 | ngpc |
| Dengeki Construction - Ochigee Yarou ze! | 1998 | ps1 |
| Deroon Dero Dero | 1995 | ps1 |
| Deroon DeroDero | 1995 | arcade, ps1 |
| Deroon DeroDero / Tecmo Stackers | 1996 | arcade |
| Desafio Chines | 1980 | o2 |
| Despicable Me - The Game - Minion Mayhem | 2010 | nds |
| Desta: The Memories Between | 2023 | switch |
| Destructo 2 | 2003 | ps1 |
| Detective Mouse | 2003 | ps1 |
| Detonator | 2002 | ps2 |
| Devil World | 1984 | nes, wiiu |
| Devilish | 1991 | genesis, gg |
| Dexter's Laboratory - Chess Challenge | 2002 | gba |
| Dexterity | 1990 | gb |
| Dharma Doujou | 1995 | snes |
| Diablobetes | 2019 | nes |
| Dice Puzzle | 1983 | a2600 |
| Diddl Puzzle - Echter Puzzlespass fuer Unterwegs | 2004 | nds |
| Die Maus | 1997 | gb |
| Die Maus | 1999 | gbc |
| Dig Dug II | 1985 | arcade, fds, nes |
| Dig Dug II - Trouble in Paradise | 1989 | nes |
| Digger Man | 2000 | arcade, neogeo |
| Digger T. Rock - The Legend of the Lost City | 1990 | nes |
| Digging for Dinosaurs | 2010 | nds |
| DigiCro - Digital Number Crossword | 1996 | ps1 |
| Dimo's Quest | 1994 | cdi |
| Diner Dash | 2007 | nds, psp, wii |
| Diner Dash | 2009 | ps3, xbox360 |
| Dinosaurs | 2003 | ps1, ps2 |
| Disney Think Fast - The Quiz Game | 2009 | wii |
| Diva Girls - Diva Dancers | 2009 | nds |
| Dizzy - Sheep Disaster | 2017 | nes |
| Do the Same | 2024 | sms |
| Doc Clock - The Toasted Sandwich of Time | 2011 | ps3, wii |
| Doctor Lautrec to Boukyaku no Kishidan | 2011 | 3ds |
| Doki Doki Idol Star Seeker | 2001 | arcade |
| Doki Doki Idol Star Seeker Remix | 2002 | dreamcast |
| Doki Doki Penguin Land | 1985 | sg1000 |
| Doki Doki Shutter Chance - Koi no Puzzle o Kumitatete | 1997 | ps1 |
| Dolmen | 1995 | arcade |
| Dolucky no Puzzle Tour '94 | 1994 | snes |
| Don-chan Puzzle - Hanabi de Doon! Advance | 2004 | gba |
| Dongbang Jiju | 1995 | arcade |
| Dongguri Techi Jakjeon | 1993 | genesis |
| Doodle Devil | 2016 | ps3, ps4 |
| Doodle Devil | 2013 | vita |
| Doodle God | 2013 | ps3, ps4, vita |
| Doodle God: Crime City | 2018 | xboxone |
| Doodle God: Evolution | 2019 | ps4, xboxone |
| Doodle God: Ultimate Edition | 2017 | xboxone |
| Doodle Kingdom | 2015 | ps3, vita |
| Doppel Effect | 2024 | nes |
| Dossun! Ganseki Battle | 1994 | snes |
| Dot Defense | 2010 | psp |
| Dou Zhi Pinpan - Wisdom Boy | 1989 | nes |
| Double Cooked | 2018 | genesis |
| Double Dealer | 1991 | arcade |
| Double Point | 1995 | arcade |
| Double Sequence - The Q-Virus Invasion | 2008 | nds |
| Double Symbol | 2019 | genesis |
| Doubutsu Chara Navi Uranai 2 - Kosei Shinrigaku + Ren'ai Uranai Puzzle | 2003 | ps1 |
| Douga de Puzzle da! Puppukupuu | 1995 | ps1 |
| Dr Kawashima's Brain Training for Nintendo Switch | 2019 | switch |
| Dr. HELLO | 1991 | sms |
| Dr. Luigi | 2013 | wiiu |
| Dr. Mario | 1990 | arcade, gb, nes, snes |
| Dr. Mario & Bactericida | 2008 | wii |
| Dr. Mario & Bactericide | 2008 | wii |
| Dr. Mario & Bazillenjagd | 2008 | wii |
| Dr. Mario & Germ Buster | 2008 | wii |
| Dr. Mario & Germ Buster - Friend Battle | 2008 | wii |
| Dr. Mario & Saikin Bokumetsu | 2008 | wii |
| Dr. Mario & Sterminavirus | 2008 | wii |
| Dr. Mario - Miracle Cure | 2016 | 3ds |
| Dr. Mario 64 | 2001 | n64 |
| Dr. Mario Online Rx | 2008 | wii |
| Dr. Robotnik's Mean Bean Machine | 1993 | genesis, gg, sms, wii |
| Dr. Seuss - Fix-Up the Mix-Up Puzzler | 1984 | col |