| Ninku 2 - Tenkuuryuu-e no Michi | 1995 | gg |
| Ninpen Manmaru | 1997 | saturn |
| Nintendo Campus Challenge 1992 | 1992 | snes |
| Nix - The Paradox Relic | 2020 | nes |
| No Rules - Get Phat | 2001 | gba |
| No Time to Explain | 2015 | ps4, xboxone |
| Noah's Ark | 1992 | nes |
| Noddy - A Day in Toyland | 2006 | gba |
| Noddy and the Birthday Party | 2000 | gbc |
| Nom Nom Galaxy | 2015 | ps4 |
| Nomolos - Storming the CATsle | 2014 | nes |
| Noobow | 1992 | gb |
| Nos Voisins, les Hommes | 2004 | nds |
| Nosey Joe - The Power Mystery | 2023 | nes |
| Nova the Squirrel | 2018 | nes |
| Number Crash | 1983 | arcade |
| Nunchackun | 1985 | arcade |
| Nuts & Milk | 1984 | nes, wiiu |
| NyxQuest - Kindred Spirits | 2009 | wii |
| Obake no Q Tarou - Wanwan Panic | 1985 | nes |
| Obocchama-kun | 1991 | pcengine |
| Ochaken no Yume Bouken | 2005 | gba |
| Octahedron | 2018 | xboxone |
| Odallus: The Dark Call | 2019 | ps4, switch, xboxone |
| Oddworld - Abe's Oddysee - New 'n' Tasty! | | ps3 |
| Oddworld - Munch's Oddysee | 2001 | gba, xbox |
| Oddworld - Munch's Oddysee HD | 2012 | ps3 |
| Oddworld - Munch's Oddysee HD | 2014 | vita |
| Oddworld Adventures | 1998 | gb |
| Oddworld Adventures 2 | 2000 | gbc |
| Oddworld: Munch's Oddysee | 2020 | switch |
| Oddworld: New 'n' Tasty! | 2014 | ps3, ps4, vita, wiiu, xboxone |
| Oira Jajamaru! Sekai Daibouken | 1990 | gb |
| Okaasan to Issho - Niko Niko Pun | 1991 | pcengine |
| OkunoKa Madness | 2020 | ps4, switch |
| Old Towers | 2024 | nes |
| Oli Bug | 1982 | arcade |
| OlliOlli: Switch Stance | 2019 | switch |
| On a Roll 3D | 2018 | xboxone |
| One Hand Clapping | 2021 | switch |
| One Piece | 2005 | gba |
| One Piece: Pirate Warriors 4 | 2020 | ps4, switch, xboxone |
| One Tap Hero | 2015 | vita |
| Oniken | 2019 | ps4, xboxone |
| Onirike | 2021 | ps4, switch, xboxone |
| Operation Secret Storm | 1991 | nes |
| Ordinary Gerbil | 2024 | genesis |
| Ore ga Omae o Mamoru | 2009 | nds |
| Orebody - Binder's Tale | 2022 | nes |
| Oretachi Geesen Zoku - Akumajou Dracula | 2006 | ps2 |
| Organic Panic | 2016 | ps4, xboxone |
| Osman | 1996 | arcade |
| Osomatsu-kun Hachamecha Gekijou | 1988 | genesis |
| Ottifanten - Kommando Stoertebeker | 2001 | gbc |
| The Ottifants | 1993 | genesis, gg, sms |
| Otto's Ottifanten - Baby Bruno's Alptraum | 1998 | gb |
| Out of Line | 2021 | switch |
| Outer World | 1994 | 3do |
| Over the Hedge | 2006 | nds |
| Over the Hedge - Hammy Goes Nuts! | 2006 | psp |
| Overstorm | 2003 | gba |
| Ovivo | 2019 | ps4, xboxone |
| Ozzy & Drix | 2003 | gba |
| P-Man GB | 1995 | gb |
| PC Genjin - Pithecanthropus Computerurus | 1989 | pcengine |
| PC Genjin - Pithecanthropus Computerus | | wii |
| PC Genjin 2 | 2014 | wiiu |
| PC Genjin 2 - Pithecanthropus Computerurus | 1991 | pcengine |
| PC Genjin 3 | 2014 | wiiu |
| PC Genjin 3 - Pithecanthropus Computerurus | 1993 | pcengine |
| PLOID | 2020 | nes |
| POWA! | 2020 | gbc |
| PROTO DERE .NES | 2019 | nes |
| Pac'n Roll | 2005 | nds |
| Pac-In-Time | 1994 | gb, gg, snes |
| Pac-Kong | 1983 | a2600 |
| Pac-Land | 1991 | lynx |
| Pac-Land | 1985 | nes, pcengine |
| Pac-Land | 1984 | arcade |
| Pac-Man Museum + | 2022 | ps4, switch, xboxone |
| Pac-Man World | 2004 | gba |
| Pac-Man World | 1999 | ps1 |
| Pac-Man World - 20th Anniversary | 1999 | ps1 |
| Pac-Man World 2 | 2002 | gba, gc, ps2, xbox |
| Pac-Man World 2 Re-Pac | 2025 | switch |
| Pac-Man World 3 | 2005 | gc, nds, ps2, psp, xbox |
| Pac-Man World Re-Pac | 2022 | ps4, switch |
| Pac-Man and the Ghostly Adventures | 2013 | 3ds, ps3, wiiu, xbox360 |
| Pac-Man and the Ghostly Adventures 2 | 2014 | 3ds, ps3, wiiu, xbox360 |
| Pac-World 2 | 2014 | 3ds |
| Packy & Marlon | 1995 | snes |
| Page Chronica | 2012 | ps3 |
| Pajama Hero - Nemo | 1990 | nes |
| Pallurikio | 2009 | wii |
| Panda Baby | 1997 | nes |
| Panda Hero | 2019 | ps4 |
| Panda Love | 2016 | wiiu |
| The Panda Prince | 1996 | nes |
| Pandemonium 2 | 1997 | ps1 |
| Pandemonium 2 | 1997 | ps1 |