| Burning Force | Mega Drive / Genesis | US | 1990-10 |
| Burning Force | Mega Drive / Genesis | WORLD | 1990-10 |
| ESWAT - City under Siege | Mega Drive / Genesis | US | 1990-10 |
| Fire Shark | Mega Drive / Genesis | US | 1990-10 |
| Fire Shark | Mega Drive / Genesis | WORLD | 1990-10 |
| Insector X | Mega Drive / Genesis | US | 1990-10 |
| Phelios | Mega Drive / Genesis | US | 1990-10 |
| Rastan Saga II | Mega Drive / Genesis | JP | 1990-10 |
| The Revenge of Shinobi | Mega Drive / Genesis | EU | 1990-10 |
| Thunder Force III | Mega Drive / Genesis | US | 1990-10 |
| Whip Rush | Mega Drive / Genesis | US | 1990-10 |
| A Nightmare on Elm Street | Nintendo Entertainment System | US | 1990-10 |
| Akumajou Special - Boku Dracula-kun | Nintendo Entertainment System | JP | 1990-10 |
| Bloody Warriors - Shan-Go no Gyakushuu | Nintendo Entertainment System | JP | 1990-10 |
| Caveman Games | Nintendo Entertainment System | US | 1990-10 |
| Days of Thunder | Nintendo Entertainment System | US | 1990-10 |
| Downtown - Nekketsu Koushinkyoku - Soreyuke Daiundoukai | Nintendo Entertainment System | JP | 1990-10 |
| Dr. Mario | Nintendo Entertainment System | US | 1990-10 |
| Dragon Ball Z - Kyoushuu! Saiya Jin | Nintendo Entertainment System | JP | 1990-10 |
| Gremlins 2 - The New Batch | Nintendo Entertainment System | US | 1990-10 |
| Kid Dracula | Nintendo Entertainment System | WORLD | 1990-10 |
| Loopz | Nintendo Entertainment System | US | 1990-10 |
| Mendel Palace | Nintendo Entertainment System | US | 1990-10 |
| Mendel Palace | Nintendo Entertainment System | EU | 1990-10 |
| Mizushima Shinji no Daikoushien | Nintendo Entertainment System | JP | 1990-10 |
| Orb-3D | Nintendo Entertainment System | US | 1990-10 |
| Sesame Street - Big Bird's Hide & Speak | Nintendo Entertainment System | US | 1990-10 |
| Super Glove Ball | Nintendo Entertainment System | US | 1990-10 |
| Battle Royale | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Boxyboy | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Bravoman | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Drop Off | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Legendary Axe II | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Ninja Spirit | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Psychosis | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Ryuukyuu | PC Engine / TurboGrafx-16 | JP | 1990-10 |
| Tiger Road | PC Engine / TurboGrafx-16 | US | 1990-10 |
| Balloon Kid | Game Boy | US | 1990-10-05 |
| Uoozu | Game Boy | JP | 1990-10-05 |
| Rainbow Islands Extra | Mega Drive / Genesis | JP | 1990-10-05 |
| Gun Nac | Nintendo Entertainment System | JP | 1990-10-05 |
| The Pro Yakyuu | PC Engine / TurboGrafx-16 | JP | 1990-10-05 |
| SD Gundam Gaiden - Lacroan' Heroes | Game Boy | JP | 1990-10-06 |
| Columns | Game Gear | JP | 1990-10-06 |
| Columns | Game Gear | BR | 1990-10-06 |
| Pengo | Game Gear | JP | 1990-10-06 |
| Super Monaco GP | Game Gear | JP | 1990-10-06 |
| Super Monaco GP | Game Gear | BR | 1990-10-06 |
| The Super Spy | Neo Geo AES | ? | 1990-10-08 |
| Jantei Monogatari | PC Engine / TurboGrafx-16 | JP | 1990-10-09 |
| Astro Rabby | Game Boy | JP | 1990-10-12 |
| Palamedes | Game Boy | JP | 1990-10-12 |
| TwinBee da!! | Game Boy | JP | 1990-10-12 |
| Fatman | Mega Drive / Genesis | JP | 1990-10-12 |
| Final Zone | Mega Drive / Genesis | JP | 1990-10-12 |
| Final Zone | Mega Drive / Genesis | WORLD | 1990-10-12 |
| Batman | PC Engine / TurboGrafx-16 | JP | 1990-10-12 |
| Cyber Knight | PC Engine / TurboGrafx-16 | JP | 1990-10-12 |
| Ghostbusters II | Game Boy | JP | 1990-10-16 |
| Monster Truck | Game Boy | JP | 1990-10-19 |
| Roadster | Game Boy | JP | 1990-10-19 |
| Burning Force | Mega Drive / Genesis | JP | 1990-10-19 |
| Akumajou Special - Boku Dracula-kun | Nintendo Entertainment System | WORLD | 1990-10-19 |
| Majaventure - Mahjong Senki | Nintendo Entertainment System | JP | 1990-10-19 |
| Rabio Lepus Special | PC Engine / TurboGrafx-16 | JP | 1990-10-19 |
| Arrow Flash | Mega Drive / Genesis | JP | 1990-10-20 |
| Tel-Tel Stadium | Mega Drive / Genesis | JP | 1990-10-21 |
| Shufflepuck Cafe | Nintendo Entertainment System | JP | 1990-10-21 |
| Amida | Game Boy | JP | 1990-10-23 |
| Zan Gear | Game Gear | JP | 1990-10-23 |
| Oeka Kids - Anpanman to Oekaki Shiyou!! | Nintendo Entertainment System | JP | 1990-10-25 |
| After Burst | Game Boy | JP | 1990-10-26 |
| Velious - Roland no Majuu | Game Boy | JP | 1990-10-26 |
| Astro Fang - Super Machine | Nintendo Entertainment System | JP | 1990-10-26 |
| Bionic Commando | Nintendo Entertainment System | EU | 1990-10-26 |
| Bubble Bobble | Nintendo Entertainment System | EU | 1990-10-26 |
| Nantettatte!! Baseball | Nintendo Entertainment System | JP | 1990-10-26 |
| Pachio-kun 3 | Nintendo Entertainment System | JP | 1990-10-26 |
| Paperboy | Nintendo Entertainment System | EU | 1990-10-26 |
| Naxat Stadium | PC Engine / TurboGrafx-16 | JP | 1990-10-26 |
| Dynamite Duke | Mega Drive / Genesis | WORLD | 1990-10-27 |
| Boxy Boy | Arcade | ? | 1990-11 |
| Boxy Boy | Arcade | WORLD | 1990-11 |
| Cyber-Lip | Arcade | ? | 1990-11 |
| Double Dragon 3: The Rosetta Stone | Arcade | JP | 1990-11 |
| Double Dragon 3: The Rosetta Stone | Arcade | US | 1990-11 |
| Gals Panic | Arcade | ? | 1990-11 |
| Gals Panic | Arcade | JP | 1990-11 |
| Gals Panic | Arcade | KR | 1990-11 |
| Gals Panic | Arcade | TW | 1990-11 |
| Gals Panic | Arcade | US | 1990-11 |
| Puzzled / Joy Joy Kid | Arcade | ? | 1990-11 |
| Souko Ban Deluxe | Arcade | JP | 1990-11 |
| Puzzle Boys | Famicom Disk System | JP | 1990-11 |
| Bubble Ghost | Game Boy | US | 1990-11 |
| Fushigina Blobby - Princess Blob o Sukue! | Game Boy | JP | 1990-11 |
| Ishido - The Way of Stones | Game Boy | US | 1990-11 |
| Kakomunja | Game Boy | JP | 1990-11 |
| Ninja Boy | Game Boy | US | 1990-11 |
| Wizards & Warriors X - The Fortress of Fear | Game Boy | EU | 1990-11 |