| Smart Girl's Magical Book Club | US | 2005 |
Tommo | Commercial |
| Super Monkey Ball - Touch & Roll | US | 2005 |
Sega | Commercial |
| Spider-Man 2 | JP | 2005-01 |
Activision | Commercial |
| Space Invaders DS | JP | 2005-03 |
Mastiff | Commercial |
| Spider-Man 2 | EU | 2005-03 |
Activision | Commercial |
| Super Mario 64 DS | EU | 2005-03 |
Nintendo | Commercial |
| SD Gundam G Generation DS | JP | 2005-05 |
Bandai | Commercial |
| Star Wars - Episode III - Revenge of the Sith | EU | 2005-05 |
Ubisoft | Commercial |
| Star Wars - Episode III - Revenge of the Sith | US | 2005-05 |
Ubisoft | Commercial |
| Simple DS Series Vol. 1 - The Mahjong | JP | 2005-06 |
D3 Publisher | Commercial |
| Simple DS Series Vol. 2 - The Billiard | JP | 2005-06 |
D3 Publisher | Commercial |
| Simple DS Series Vol. 3 - The Mushitori Oukoku - Shinshu Hakken! Nokogiri Kabuto! | JP | 2005-06 |
D3 Publisher | Commercial |
| Space Invaders Revolution | EU | 2005-07 |
Mastiff | Commercial |
| Space Invaders Revolution | US | 2005-07 |
Mastiff | Commercial |
| Star Wars - Episode III - Sith no Fukushuu | JP | 2005-07 |
Ubisoft | Commercial |
| Survival Kids - Lost in Blue | JP | 2005-08 |
Konami | Commercial |
| Scooby-Doo! - Unmasked | EU | 2005-10 |
THQ | Commercial |
| Scooby-Doo! - Unmasked | US | 2005-10 |
THQ | Commercial |
| Simple DS Series Vol. 4 - The Block Kuzushi | JP | 2005-10 |
D3 Publisher | Commercial |
| Spyro - Shadow Legacy | US | 2005-10 |
Sierra Entertainment | Commercial |
| Spyro - Shadow Legacy | US | 2005-10 |
Sierra Entertainment | Prototype |
| Super Princess Peach | JP | 2005-10 |
Nintendo | Commercial |
| SBK - Snowboard Kids | US | 2005-11 |
Atlus | Commercial |
| SEGA Casino | US | 2005-11 |
Sega | Commercial |
| Shamu's Deep Sea Adventures | EU | 2005-11 |
Activision | Commercial |
| Shamu's Deep Sea Adventures | US | 2005-11 |
Activision | Commercial |
| Shichida Shiki Training - Unou Tanren Unotan DS - Shun Kan Shoubu! Handanryoku | JP | 2005-11 |
Interchannel | Commercial |
| Shichida Shiki Training - Unou Tanren Unotan DS - Shun Kan Shoubu! Kiokuryoku | JP | 2005-11 |
Majesco Entertainment | Commercial |
| Shichida Shiki Training - Unou Tanren Unotan DS - Shun Kan Shoubu! Shuuchuuryoku | JP | 2005-11 |
Majesco Entertainment | Commercial |
| Shrek - Super Slam | EU | 2005-11 |
Activision | Commercial |
| Shrek - Super Slam | US | 2005-11 |
Activision | Commercial |
| Simple DS Series Vol. 6 - The Party Game | JP | 2005-11 |
D3 Publisher | Commercial |
| Snood 2 - On Vacation | US | 2005-11 |
Destination Software | Commercial |
| Snowboard Kids Party | JP | 2005-11 |
Atlus | Commercial |
| Sonic Rush | EU | 2005-11 |
Sega | Commercial |
| Sonic Rush | JP | 2005-11 |
Sega | Commercial |
| Sonic Rush | US | 2005-11 |
Sega | Commercial |
| SpongeBob SquarePants - The Yellow Avenger | EU | 2005-11 |
THQ | Commercial |
| SpongeBob SquarePants - The Yellow Avenger | US | 2005-11 |
THQ | Commercial |
| Spyro - Shadow Legacy | EU | 2005-11 |
Sierra Entertainment | Commercial |
| Super Black Bass - Dynamic Shot | JP | 2005-11 |
Starfish SD | Commercial |
| Shanghai | JP | 2005-12 |
Success | Commercial |
| Slime Morimori Dragon Quest 2 - Daisensha to Shippo Dan | JP | 2005-12 |
Square Enix | Commercial |
| Soreike! Anpanman - Baikinman no Daisakusen | JP | 2005-12 |
Agatsuma Entertainment | Commercial |
| Super Monkey Ball DS | JP | 2005-12 |
Sega | Commercial |