| Ragnarok Online DS | JP | 2008 |
Xseed Games | Commercial |
| Rune Factory 2 | JP | 2008-01 |
Marvelous Entertainment | Commercial |
| Ryoukiki Exercise - Riron no Migite to Kansei no Hidarite | JP | 2008-01 |
CyberFront | Commercial |
| Real Stories - Best Friends - Mon Poulain, Mon Cheval | EU | 2008-03 |
THQ | Commercial |
| Rosario to Vampire - Tanabata no Miss Youkai Gakuen | JP | 2008-03 |
Capcom | Commercial |
| Rekishi Nouryoku Kentei Kyoukai Kounin - Yamakawa Shuppansha Kanshuu - Rekiken DS - Nihonshi, Sekaishi | JP | 2008-04 |
| Commercial |
| Real Soccer 2008 | US | 2008-05 |
Ubisoft | Commercial |
| Rekishi Gunzou Presents - Monoshiri Bakumatsu Ou | JP | 2008-05 |
Global A Entertainment | Commercial |
| Rhythm Tengoku Gold | JP | 2008-07 |
Nintendo | Commercial |
| Race Driver - Grid | EU | 2008-08 |
Codemasters | Commercial |
| Real Soccer 2009 | US | 2008-08 |
Gameloft | Commercial |
| Red Bull BC One | EU | 2008-08 |
NA: Ignition Entertainment | Commercial |
| Red Bull BC One | US | 2008-08 |
Playlogic Entertainment | Commercial |
| Road to Vegas | EU | 2008-08 |
Midas Interactive Entertainment | Commercial |
| Rock Blast | US | 2008-08 |
UFO Interactive Games | Commercial |
| Rain Drops | US | 2008-09 |
UFO Interactive | Commercial |
| Real Football 2009 | EU | 2008-09 |
Gameloft | Commercial |
| Real Stories - Mission Equitation | FR | 2008-09 |
Mindscape | Commercial |
| Rhapsody - A Musical Adventure | US | 2008-09 |
Nippon Ichi Software | Commercial |
| Robbie Konijn - Leer Lezen en Schrijven | NL | 2008-09 |
Mindscape | Commercial |
| Real Stories - Fashion Shop | EU | 2008-10 |
Mindscape | Commercial |
| Rock Revolution | US | 2008-10 |
Konami | Commercial |
| Rayman - Raving Rabbids - TV Party | US | 2008-11 |
Ubisoft | Commercial |
| Real Stories - Babies | FR | 2008-11 |
Zoo Games | Commercial |
| Rhythm de Cooking - Sweets Party e Youkoso | JP | 2008-11 |
MTO | Commercial |
| Robocalypse | US | 2008-11 |
Tecmo | Commercial |
| Rubik's Puzzle World | EU | 2008-11 |
The Game Factory | Commercial |
| Rubik's World | US | 2008-11 |
The Game Factory | Commercial |
| Rune Factory 2 - A Fantasy Harvest Moon | US | 2008-11 |
Marvelous Entertainment | Commercial |
| Ryuusei no Rockman 3 - Black Ace | JP | 2008-11 |
Capcom | Commercial |
| Ryuusei no Rockman 3 - Red Joker | JP | 2008-11 |
Capcom | Commercial |
| Raku Raku Shindenzu Training DS | JP | 2008-12 |
Medicus Shuppan | Commercial |
| Rekishi Adventure - Quiz Sangokushi Tsuu DS | JP | 2008-12 |
NCS | Commercial |
| Rekishi Gunzou Presents - Monoshiri Sangokushi | JP | 2008-12 |
Global A Entertainment | Commercial |
| Riz-Zoawd | JP | 2008-12 |
D3 Publisher | Commercial |