| Ellen Whitaker's Horse Life | EU | 2008 |
Deep Silver | Commercial |
| Evolution GT | EU | 2008 |
Valcon Games | Commercial |
| E=M6 Defi Cerebral | FR | 2008-02 |
Atari | Commercial |
| Etrian Odyssey II - Heroes of Lagaard | US | 2008-02 |
Atlus | Commercial |
| Edo Bunka Rekishi Kentei DS | JP | 2008-03 |
Marvelous Entertainment | Commercial |
| Eiken-ou - 2-kyuu Hen | JP | 2008-03 |
Gakken | Commercial |
| Emblem of Gundam | JP | 2008-05 |
Namco Bandai Games | Commercial |
| Emma in the Mountains | EU | 2008-06 |
Aspyr Media | Commercial |
| Emma in the Mountains | US | 2008-06 |
Aspyr Media | Commercial |
| Ener-G - Horse Riders | US | 2008-06 |
Ubisoft | Commercial |
| Etrian Odyssey | EU | 2008-06 |
Nintendo | Commercial |
| Exit DS | EU | 2008-07 |
Taito | Commercial |
| Exit DS | US | 2008-07 |
Taito | Commercial |
| Englisch Macht Spass - Eine Reise nach London! | DE | 2008-09 |
DTP Young Entertainment | Commercial |
| Ener-G - Dance Squad | US | 2008-10 |
Ubisoft | Commercial |
| Ener-G - Gym Rockets | US | 2008-10 |
Ubisoft | Commercial |
| Equitation - Galops 1 a 7 | FR | 2008-10 |
Atari | Commercial |
| Element Girls | DE | 2008-11 |
Eidos Interactive | Commercial |
| Elminage - Yami no Miko to Kamigami no Yubiwa - DS Remix | JP | 2008-11 |
Starfish SD | Commercial |
| Emergency DS | DE | 2008-11 |
Destineer | Commercial |
| Equestrian Training | EU | 2008-11 |
Atari | Commercial |
| Equitation - Galops 1 a 4 | FR | 2008-11 |
Atari | Commercial |
| Edogawa Ranpo no Kaijin Nijuu Mensou DS | JP | 2008-12 |
Takara Tomy | Commercial |
| Elebits - Kai to Zero no Fushigi na Tabi | JP | 2008-12 |
Konami | Commercial |
| Elebits - Kaiwa Zeroui Sinbihan Yeohaeng | KR | 2008-12 |
Konami | Commercial |
| Emily - My Dog Paradise | EU | 2008-12 |
DreamCatcher Interactive | Commercial |
| Emma at the Farm | US | 2008-12 |
Aspyr Media | Commercial |