| Easy Learning - Discover Our World | EU | 2004-01 |
DreamCatcher Interactive | Commercial |
| Ecolis - Save the Forest | EU | 2004-01 |
Majesco Entertainment | Commercial |
| Eiken DS Training | JP | 2004-01 |
IE Institute | Commercial |
| Eindeloos Backgammon | NL | 2004-01 |
DTP Young Entertainment | Commercial |
| Eindeloos Mahjong 2 - Een Reis om de Wereld | NL | 2004-01 |
DTP Entertainment | Commercial |
| Eindeloos Patience | NL | 2004-01 |
Mindscape | Commercial |
| Element Girls - Love, Fashion & Friends | EU | 2004-01 |
Eidos Interactive | Commercial |
| Element Girls - Style Your Life! | EU | 2004-01 |
DTP Young Entertainment | Commercial |
| Elvenland | EU | 2004-01 |
Intenium | Commercial |
| Emergency Kids | DE | 2004-01 |
Rondomedia | Commercial |
| Emily - My Animal Shelter | EU | 2004-01 |
Ubisoft | Commercial |
| Emily - My Personal Diary | EU | 2004-01 |
Atari | Commercial |
| Emily Archer - The Curse of King Tut's Tomb | EU | 2004-01 |
Micro Application | Commercial |
| Emma at the Farm | EU | 2004-01 |
Aspyr Media | Commercial |
| Englisch Buddy | EU | 2004-01 |
Deep Silver | Commercial |
| Englisch Entdecken Mit Ben & Bella | DE | 2004-01 |
Rondomedia | Commercial |
| English Buddy | EU | 2004-01 |
Brain Games | Commercial |
| Escape the Museum | DE | 2004-01 |
GameMill Publishing | Commercial |
| Escape the Museum | EU | 2004-01 |
GameMill Publishing | Commercial |
| Escape the Museum | US | 2004-01 |
GameMill Publishing | Commercial |
| Everything's Rosie | EU | 2004-01 |
Avanquest Software | Commercial |
| EDGE | WORLD | 2004-11 |
Nintendo | Unlicensed |
| EZ-Flash V | WORLD | 2004-11 |
Sega | Unlicensed |