| Master of Monsters | US | 1991-12 |
System Soft | Commercial |
| Mike Ditka Power Football | US | 1991-12 |
Accolade | Unlicensed |
| Mondu's Fight Palace | US | 1991-12 |
RazorSoft | Prototype |
| Mugen Senshi Valis | JP | 1991-12 |
Renovation Products | Commercial |
| Nakajima Satoru Kanshuu - F1 Grand Prix | JP | 1991-12 |
Varie | Commercial |
| Nobunaga no Yabou - Bushou Fuuunroku | JP | 1991-12 |
Koei | Commercial |
| Phelios | EU | 1991-12 |
Namco | Commercial |
| Renzhe Wu lei Chuanshuo | CN | 1991-12 |
| Unlicensed |
| Sangokushi II | JP | 1991-12 |
Koei | Commercial |
| Shadow of the Beast | EU | 1991-12 |
Electronic Arts | Commercial |
| Shikong Yibian | CN | 1991-12 |
| Unlicensed |
| Speedball 2 - Brutal Deluxe | US | 1991-12 |
The Bitmap Brothers | Commercial |
| Speedball 2 - Brutal Deluxe | US | 1991-12 |
The Bitmap Brothers | Prototype |
| Speedball 2 - Brutal Deluxe | WORLD | 1991-12 |
Arena | Commercial |
| Task Force Harrier EX | US | 1991-12 |
UPL | Commercial |
| Undead Line | JP | 1991-12 |
Palsoft | Commercial |
| Valis | US | 1991-12 |
Renovation Products | Commercial |
| Valis | US | 1991-12 |
Renovation Products | Prototype |
| Ys III | US | 1991-12 |
Nihon Falcom | Commercial |
| Ys III | US | 1991-12 |
Nihon Falcom | Prototype |
| Ninja Burai Densetsu | JP | 1991-12-05 |
Sega Enterprises | Commercial |
| Ninja Burai Densetsu | JP | 1991-12-05 |
Sega Enterprises | Prototype |
| Fighting Masters | JP | 1991-12-06 |
Treco | Commercial |
| NHK Taiga Drama - Taiheiki | JP | 1991-12-13 |
NHK | Commercial |
| Dahna - Megami Tanjou | CN | 1991-12-20 |
| Unlicensed |
| Double Dragon II - The Revenge | JP | 1991-12-20 |
Tecmo | Commercial |
| Double Dragon II - The Revenge | JP | 1991-12-20 |
Tecmo | Prototype |
| F1 Circus MD | JP | 1991-12-20 |
Nichibutsu | Commercial |
| F1 Circus MD | US | 1991-12-20 |
Nichibutsu | Prototype |
| Slaughter Sport | US | 1991-12-20 |
RazorSoft | Commercial |
| Task Force Harrier EX | JP | 1991-12-20 |
Treco | Commercial |
| Golden Axe II | WORLD | 1991-12-27 |
Sega of America | Commercial |
| Golden Axe II | WORLD | 1991-12-27 |
Sega of America | Prototype |