| Snoopy Tennis | 2001 | gbc |
| Snoopy's Silly Sports Spectacular! | 1990 | nes |
| Snow Board Championship | 1996 | arcade |
| Snow Break | 1998 | ps1 |
| Snow Racer 98 | 1998 | ps1 |
| Snow Rider | 2006 | ps2 |
| Snow Speeder | 1998 | n64 |
| Snow Surfers | 1999 | dreamcast |
| Snowboard Challenge | 1990 | nes |
| Snowboard Heaven | 2000 | ps2 |
| Snowboard Kids | 1997 | n64 |
| Snowboard Kids 2 | 1999 | n64 |
| Snowboard Racer | 2003 | ps1 |
| Snowboard Riot | 2009 | wii |
| Snowboarding | 2000 | ps1 |
| Soccer | 1982 | arcadia |
| Soccer | 1985 | astrocade |
| Soccer | 1985 | fds, nes |
| Soccer | 1991 | gb |
| Soccer | 2006 | wii |
| Soccer | 2014 | wiiu |
| Soccer '97 | 1997 | ps1 |
| Soccer America - International Cup | 2000 | ps2 |
| Soccer Boy | 1990 | gb |
| Soccer Brawl | 1991 | arcade, neogeo, neogeocd |
| Soccer Champion | 1992 | svision |
| Soccer Kantoku Saihai Simulation - Formation Final | 2003 | ps2 |
| Soccer League - Winner's Cup | 1988 | nes |
| Soccer Manager | 2000 | gbc |
| Soccer Mania | 1992 | gb |
| Soccer Mania | 2002 | gba, ps2 |
| Soccer Power Hero | 2019 | xboxone |
| Soccer Shootout | 1994 | snes |
| Soccer Slammers | 2018 | switch |
| Soccer Superstars | 1994 | arcade |
| Soccer Up! | 2011 | wii |
| Soccer Yarou! - Challenge the World | 1999 | ws |
| Sociable Soccer | | ps4 |
| Softball Tengoku | 1989 | nes |
| Sonic Spike - World Championship Beach Volleyball | 1990 | pcengine |
| Soreike Flyfishing - Let's Go Flyfishing | 1999 | ps1 |
| Sougou Kakutougi - Astral Bout 2 - The Total Fighters | 1994 | snes |
| Sougou Kakutougi Rings - Astral Bout 3 | 1995 | snes |
| Soul Surfer | 2002 | arcade |
| Space Football - One on One | 1992 | snes |
| Space Jam | 1996 | ps1, saturn |
| Space Squash | 1995 | vb |
| SpaceRoads | 2016 | wiiu |
| Sparkle Snapshots 3D | 2012 | 3ds |
| Special Tee Shot | | snes |
| Speed Ball - Contest at Neonworld | 1985 | arcade |
| Speed Spin | 1994 | arcade |
| Speedball | 1991 | sms |
| Speedball 2 | 2002 | gba |
| Speedball 2 | 1992 | sms |
| Speedball 2 - Brutal Deluxe | 1992 | gb |
| Speedball 2 - Brutal Deluxe | 1991 | genesis |
| Spiegel Online - Die Wissenstrainer-Serie - Karriere Coach | 2009 | nds |
| Spiegel Online - Die Wissenstrainer-Serie - Life Coach | 2009 | nds |
| Spike Volleyball | 2019 | xboxone |
| Spiker | 1986 | arcade |
| Spiker - Super Pro Volleyball | 1989 | intv |
| SpinDrive Ping Pong | 2005 | ps2 |
| SpongeBob's Surf & Skate - Roadtrip | 2011 | nds |
| Spooky Soccer | 2022 | nes |
| Sport Fishing 2 | 1995 | arcade |
| SportStation: NBA Showtime NBA on NBC / NFL Blitz 2000 Gold Edition | 1999 | arcade |
| SportTime Bowling | 1988 | arcade |
| SportTime Table Hockey | 1988 | arcade |
| The Sporting News - Baseball | 1995 | snes |
| Sports - Football | 1994 | cd32 |
| Sports Champions | 2010 | ps3 |
| Sports Champions 2 | 2012 | ps3 |
| Sports Collection | 2010 | nds |
| Sports Connection | 2012 | wiiu |
| Sports Illustrated - Championship Football & Baseball | 1993 | gb |
| Sports Illustrated - Championship Football & Baseball | 1995 | gg |
| Sports Illustrated - Championship Football & Baseball | 1994 | snes |
| Sports Illustrated - Golf Classic | 1994 | gb |
| Sports Illustrated for Kids - Baseball | 2001 | gba |
| Sports Illustrated for Kids - Football | 2003 | gba |
| Sports Illustrated for Kids - The Ultimate Triple Dare! | 1994 | gb |
| Sports Island 2 | 2009 | wii |
| Sports Island 3D | 2011 | 3ds |
| Sports Jam | 2000 | arcade, dreamcast, naomi |
| Sports Pad Football | 1987 | sms |
| Sports Pad Soccer | 1987 | sms |
| Sports Story | 2022 | switch |
| Sports Talk Baseball | 1992 | genesis |
| Sportsball | 2014 | wiiu |
| Sportweek Player Manager 2000 | 2000 | ps1 |
| Sportweek Player Manager 2001 | 2000 | ps1 |
| Sprinter Monogatari - Mezase!! Ikkakusenkin | 1995 | snes |
| Squash | 1984 | arcade |
| Squash | 1992 | arcade |
| St. Andrews - Eikou to Rekishi no Old Course | 1995 | snes |
| St. Andrews Old Course - Eikou no St. Andrews | 1997 | ps1 |
| Stable Star - Kyuusha Monogatari | 1996 | snes |
| Stadium Events | 1987 | nes |
| Stadium Games | 2003 | gba |