| Dead or Alive Xtreme 3: Scarlet | 2019 | switch |
| Dead or Alive Xtreme Beach Volleyball | 2003 | xbox |
| Dear Boys | 1994 | snes |
| DecAthlete | 1996 | saturn |
| DecAthlete for SegaNet | 1997 | saturn |
| Deca Sporta - 3D Sports | 2011 | 3ds |
| Deca Sporta - Wii de Sports 10 Shumoku! | 2008 | wii |
| Deca Sporta - Wiiro Jeulgineun Sports 10 Jongmok! | 2009 | wii |
| Deca Sports | 2008 | wii |
| Deca Sports DS | 2008 | nds |
| Deca Sports Extreme | 2011 | 3ds |
| Decathlete | 1996 | arcade, saturn |
| Decathlon | 1997 | 3do |
| Decathlon | 1992 | nes |
| Deco Photo 3D | 2012 | 3ds |
| Deep Pockets - Super Pro Pool & Billiards | 1990 | intv |
| Deepak Chopra's Leela | 2011 | wii |
| Deepak Chopra's Leela | 2012 | xbox360 |
| Deer Captor | 2010 | wii |
| Deer Drive Legends | 2012 | 3ds, wii |
| Deer Drive Legends | 2019 | switch |
| Deer Hunter | 1999 | gbc |
| Deer Hunter | 2003 | ps2 |
| Deer Hunting King | 2013 | 3ds |
| Der Gesundheits Coach - Wohlfuehlen Jeden Tag | 2010 | nds |
| Der Gesundheitscoach | 2010 | wii |
| Derby Derby | 1981 | arcade |
| Derby Jockey - Kishu Ou e no Michi | 1994 | snes |
| Derby Jockey 2 | 1995 | snes |
| Derby Owners Club | 1999 | arcade |
| Derby Owners Club 2000 Ver.2 | 2000 | arcade |
| Derby Owners Club II Ver.2.1 | 2001 | arcade |
| Derby Owners Club World Edition | 2001 | arcade |
| Derby Owners Club World Edition EX | 2005 | arcade |
| Derby Stallion | 1999 | saturn |
| Derby Stallion | 2020 | switch |
| Derby Stallion - Zenkoku Ban | 1992 | nes |
| Derby Stallion 04 | 2004 | ps2 |
| Derby Stallion 64 | 2001 | n64 |
| Derby Stallion 96 | 1996 | snes |
| Derby Stallion 98 | 1998 | snes |
| Derby Stallion Advance | 2002 | gba |
| Derby Stallion DS | 2008 | nds |
| Derby Stallion Gold | 2014 | 3ds |
| Derby Stallion II | 1994 | snes |
| Derby Stallion III | 1995 | snes |
| Derby Stallion P | 2006 | psp |
| Derby Time | 2005 | psp |
| Derby Time 2006 | 2006 | psp |
| Derby Time Online | 2008 | ps3 |
| Derby-ba o Tsukurou! 5 | 2006 | ps2 |
| Descenders | 2020 | ps4, switch |
| Desi Adda - Games of India | 2009 | ps2, psp |
| Despelote | 2025 | switch |
| Diamond Derby | 1986 | arcade |
| Dick Vitale's 'Awesome, Baby!' College Hoops | 1994 | genesis |
| Die Wilden Fussball-Kerle - Entscheidung im Teufelstopf | 2006 | gba |
| Die Wilden Fussball-Kerle - Gefahr im Wilde Kerle Land | 2007 | gba |
| Dig & Spike Volleyball | 1993 | snes |
| Digical League | 1997 | ps1 |
| Digital Champ | | wii |
| Digital Champ - Battle Boxing | 1989 | pcengine |
| Digital Champ Battle Boxing | 2008 | wii |
| Dino Dini's Kick Off Revival | 2017 | vita |
| Dino Dini's Soccer! | 1994 | genesis, snes |
| Dino Hockey | 1991 | nes |
| Dirt Champ Motocross No. 1 | 2000 | ps1 |
| Dirty Pigskin Football | 2006 | arcade |
| Disc Jam | 2017 | ps4, switch |
| Disney Golf | 2002 | ps2 |
| Disney Golf Classic | 2002 | ps2 |
| Disney Sports - Basketball | 2002 | gba, gc |
| Disney Sports - Football | 2002 | gba, gc |
| Disney Sports - Skateboarding | 2002 | gba, gc |
| Disney Sports - Snowboarding | 2003 | gba |
| Disney's Extreme Skate Adventure | 2003 | gc, ps2, xbox |
| Diva Girls - Princess on Ice | 2009 | nds, wii |
| Doala de Wii | 2009 | wii |
| Doc Louis's Punch-Out!! | 2009 | wii |
| Dodge Boy | 1991 | gb |
| Dodge It | 1978 | channelf |
| Dodgeball | 2004 | ps2 |
| Dodgeball Academia | 2021 | ps4, switch, xboxone |
| Dolucky no A.League Soccer | 1994 | snes |
| Dolucky no Kusayakiu | 1993 | snes |
| Don Bradman Cricket 14 | 2014 | ps3, xbox360, xboxone |
| Don Bradman Cricket 17 | 2016 | ps4, xboxone |
| Don King Boxing | 2004 | nds |
| Don King Boxing | 2009 | wii |
| Don King Presents - Prizefighter | 2008 | xbox360 |
| Donald Duck | 1988 | nes |
| Dorabase - Doraemon Super Baseball Gaiden - Dramatic Stadium | 2007 | nds |
| Dorabase 2 - Nettou Ultra Stadium | 2009 | nds |
| Dotchi de Ball! | 1998 | ps1 |
| Double D Dodgeball | 2008 | xbox360 |
| Double Dribble | 1986 | arcade, fds, nes |
| Double Dribble | 2007 | wii |
| Double Dribble - 5 on 5 | 1991 | gb |
| Double Dunk | 1989 | a2600 |
| Double Play | 1977 | arcade |