| Eagle Plan | 1992 | svision |
| Earth Command | 1994 | cdi |
| Eberouge | 1997 | ps1, saturn |
| Eberouge 2 | 1999 | ps1 |
| Eberouge Special - Koi to Mahou no Gakuen Seikatsu | 1998 | ps1 |
| Eberouge Special - Koi to Mahou no Gakuen Seikatsu | 1998 | saturn |
| Eclipse | 1992 | gb |
| Ecolibrium | 2012 | vita |
| Edomono | 2005 | ps2 |
| Efficus - Kono Omoi o Kimi ni | 1998 | ps1 |
| Eikan wa Kimi ni - Koukou Yakyuu Zenkoku Taikai | 1994 | pcengine |
| Eikan wa Kimi ni 2002 - Koushien no Kodou | 2002 | ps2 |
| Eikan wa Kimi ni 4 | 1999 | ps1 |
| Eiyuu Senki - The World Conquest | 2015 | ps3 |
| Elan | 1999 | ps1 |
| Elan Plus | 2000 | ps1 |
| Element Girls - Love, Fashion & Friends | 2004 | nds |
| Element Girls - Style Your Life! | 2004 | nds |
| Elfin Paradise | 1997 | ps1 |
| Elite | | genesis |
| Elite | 1991 | nes |
| Elite | 1991 | nes |
| Ellen Whitaker's Horse Life | 2008 | nds |
| Emergency DS | 2008 | nds |
| Emergency Room - Real Life Rescues | 2009 | nds |
| Emily - My Animal Shelter | 2004 | nds |
| Emily - My Dog Paradise | 2008 | nds |
| Emily - My Personal Diary | 2004 | nds |
| Enchanted Folk and the School of Wizardry | 2009 | nds |
| Endonesia | 2001 | ps2 |
| Ener-G - Horse Riders | 2008 | nds |
| Energy Airforce | 2002 | ps2 |
| Epic Astro Story | 2019 | ps4, switch |
| Euro Fishing | 2017 | ps4 |
| Everdream Valley | 2023 | switch |
| Expeditions: A MudRunner Game | 2024 | ps4, switch, xboxone |
| EyePet | 2009 | ps3 |
| EyePet | 2010 | psp |
| EyePet & Friends | 2011 | ps3 |
| EyePet - Move Edition | 2010 | ps3 |
| EyePet Adventures | 2011 | psp |
| F-1 Grand Prix 1996 - Team Un'ei Simulation | 1997 | ps1 |
| F-117 Night Storm | 1993 | genesis |
| F-117 Stealth - Operation - Night Storm | 1994 | genesis |
| F-14 Tomcat | 2001 | gba |
| F-15 Strike Eagle | 1993 | gb, gg |
| F-15 Strike Eagle | 1991 | arcade, nes |
| F-15 Strike Eagle II | 1993 | gb |
| F-15 Strike Eagle II | 1993 | genesis |
| F-15 Super Strike Eagle | 1993 | snes |
| F-16 Fighter | 1986 | sms |
| F-16 Fighting Falcon | 1985 | sms |
| F-18 Hornet | 1988 | a7800 |
| F-18 Thunder Strike | 2000 | gbc |
| F-22 Interceptor | 1991 | genesis |
| F-22 Interceptor - Advanced Tactical Fighter | 1991 | genesis |
| F-24 - Stealth Fighter | 2007 | nds |
| F1 GP Nippon no Chousen - Dome no Yabou | 1996 | ps1 |
| F1 Manager 2023 | 2023 | ps4, xboxone |
| F1 Team Simulation - Project F | 1992 | pcengine |
| F24 Stealth Fighter | 2007 | gba |
| FINes | 2021 | nes |
| FabStyle | 2011 | 3ds, nds |
| Fae Farm | 2023 | switch, xboxone |
| Falcon | 1992 | pcengine, snes |
| The Falconeer | 2020 | xboxone |
| The Falconeer: Warrior Edition | 2021 | ps4, switch |
| FamiDepth | 2017 | nes |
| Famicom Top Management | 1990 | nes |
| Family Park Tycoon | 2008 | nds |
| Fantastic Fortune | 2001 | ps1 |
| Fantastic Fortune 2 | 2003 | ps2 |
| Fantastic Fortune 2 - Triple Star | 2005 | ps2 |
| Fantasy Aquarium World | 2009 | wii |
| Fantasy Aquarium by DS | 2004 | nds |
| Fantasy Life Link! | 2014 | 3ds |
| Fantasy Life i: The Girl Who Steals Time | 2025 | ps4, switch |
| Farm Frenzy - Animal Country | 2010 | nds |
| Farm Life - Manage Your Own Farm | 2007 | nds |
| Farmer's Dynasty | 2019 | xboxone |
| Farming Simulator | 2013 | ps3, vita, xbox360 |
| Farming Simulator 14 | 2014 | 3ds, vita |
| Farming Simulator 15 | 2015 | ps3, ps4, xbox360, xboxone |
| Farming Simulator 16 | 2015 | vita |
| Farming Simulator 17 | 2016 | ps4, xboxone |
| Farming Simulator 18 | 2017 | 3ds, vita |
| Farming Simulator 18 - Pocket Nouen 4 | 2017 | 3ds |
| Farming Simulator 19 | 2018 | ps4, xboxone |
| Farming Simulator 20 | 2019 | switch |
| Farming Simulator 2012 3D | 2012 | 3ds |
| Farming Simulator 2018 | 2017 | vita |
| Farming Simulator 22 | 2021 | ps4 |
| Farming Simulator 3D - Pocket Nouen | 2014 | 3ds |
| Farmtopia | 2010 | nds |
| Fashion Designer - Style Icon | 2004 | nds |
| Fashion Dogz | 2008 | nds |
| Fashion Tycoon | 2010 | nds |
| Fast Food Panic | 2009 | nds, wii |
| Ferret Monogatari | 2000 | gbc |
| Fever - Sankyo Koushiki Pachinko Simulation for WonderSwan | 1999 | ws |