| X2 - No Relief | 1996 | ps1 |
| X2222 | 2000 | arcade |
| X80 - War Command | 1981 | arcade |
| XDR - X-Dazedly-Ray | 1990 | genesis |
| XG Blast! | 2009 | nds |
| XII Stag | 2002 | arcade, ps2 |
| XIII | 2003 | gc, ps2, xbox |
| XIII | 2020 | ps4, switch, xboxone |
| XIII - Daitouryou o Koroshita Otoko | 2004 | ps2 |
| XType Plus | 2014 | wiiu |
| XX Mission | 1986 | arcade |
| Xeno Crisis | 2018 | dreamcast, gc, genesis, neogeo, neogeocd, ps4, switch, vita, xboxone |
| XenoRaptor | 2019 | ps4, xboxone |
| Xenon | 1988 | arcade |
| Xenon 2 | 1992 | gb |
| Xenon 2 - Megablast | 1992 | gb |
| Xenon 2 - Megablast | 1991 | genesis, sms |
| Xenophobe | 1990 | lynx |
| Xenophobe | 1987 | arcade |
| Xenoraid | 2016 | ps4, vita, xboxone |
| Xevios | 1982 | arcade |
| Xevious | 1984 | a2600, a5200 |
| Xevious | 1982 | a7800, arcade, fds, nes |
| Xevious - Fardraut Densetsu | 1990 | pcengine |
| Xevious - The Avenger | 1988 | nes |
| Xevious - The Avenger | 1988 | nes |
| Xevious 3D/G | 1995 | arcade, ps1 |
| Xexex | 1991 | arcade |
| Xiao Monu - Magic Girl | 1993 | genesis |
| Xotic | 2011 | xbox360 |
| Xyanide | 2008 | ps2 |
| Xyanide | 2007 | psp |
| Xyanide | 2006 | xbox |
| Xyanide - Resurrection | 2007 | ps2, psp |
| Xybots | 1987 | arcade, lynx |
| Xybots | 1991 | nes |
| Yamato | 1983 | arcade, sg1000 |
| Yars' Revenge | 1999 | gbc |
| Yars' Revenge | | xbox360 |
| Yars: Recharged | 2022 | switch |
| Yet Another Zombie Defense HD | 2018 | xboxone |
| Yo' Bro | 1991 | pcengine |
| Yobarai Detective: Miasma Breaker | 2025 | switch |
| Yosaku to Donbei | 1979 | arcade |
| Youjyuden | 1986 | arcade |
| Youkai Douchuuki ) | 1987 | arcade |
| Youma Ninpou Chou | 1986 | arcade |
| Yurukill: The Calumniation Games | 2022 | ps4, switch |
| Yuu Yuu Hakusho - Yami Shoubu!! Ankoku Bujutsu-kai | 1993 | pcengine |
| Yuusei kara no Buttai X - Episode II | 2002 | ps2 |
| ZAS | 1992 | gb |
| ZPF | 2023 | genesis |
| Zaku | 2009 | lynx |
| Zamb! Redux | 2018 | xboxone |
| Zanac | 1986 | fds, nes |
| Zanac | 2007 | wii |
| Zarlor Mercenary | 1990 | lynx |
| Zarzon | 1981 | arcade |
| Zaviga | 1984 | arcade |
| Zaxxon | 1982 | a2600, a5200, arcade, col, intv, sg1000 |
| Zaxxon | 2010 | wii |
| Zaxxon 3-D | 1987 | sms |
| Zed Blade / Operation Ragnarok | 1994 | arcade |
| Zegapain NOT | 2006 | xbox360 |
| Zeitgeist | 1995 | ps1 |
| Zektor | 1982 | arcade |
| Zenith | 1997 | cdi |
| Zeno Clash II | 2013 | ps3, xbox360 |
| Zero | 1980 | arcade |
| Zero 5 | 1997 | jaguar |
| Zero Gunner | 1997 | arcade |
| Zero Gunner 2 | 2001 | arcade, dreamcast |
| Zero Gunner 2- | 2022 | ps4 |
| Zero Hour | 1980 | arcade |
| Zero Pilot - Gin'yoku no Senshi | 1998 | ps1 |
| Zero Point | 1998 | arcade |
| Zero Point 2 | 1999 | arcade |
| Zero Strain | 2020 | ps4 |
| Zero Target | 1985 | arcade |
| Zero Time | 1979 | arcade |
| Zero Tolerance | 1994 | genesis |
| Zero Tolerance Underground | 1994 | genesis |
| Zero Wing | 1989 | arcade, genesis, pcengine |
| Zero no Tsukaima - Fantasy Force | 2007 | ps2 |
| Zero no Tsukaima - Fantasy Force 2nd Impact | 2008 | ps2 |
| Zeroptian Invasion | 2019 | vita |
| Zeroptian Invasion | 2019 | xboxone |
| Ziggurat | 2015 | ps4, wiiu, xboxone |
| Ziggurat | 2019 | switch |
| Zing Zing Zip | 1992 | arcade |
| Zing Zing Zip / Zhen Zhen Ji Pao | 1992 | arcade |
| Zodiack | 1983 | arcade |
| Zoids Densetsu | 1990 | gb |
| Zoids Vs | 2002 | gc |
| Zoids Vs. III | 2004 | gc |
| Zombeer | 2014 | ps3, wiiu |
| Zombie Apocalypse | 2009 | ps3, xbox360 |
| Zombie Army Trilogy | 2015 | ps4, switch, xboxone |
| Zombie Nation | 1991 | nes |
| Zombie Panic in Wonderland | 2010 | wii |