| Turok: Dinosaur Hunter | 2019 | switch |
| Turok: Dinosaur Hunter | 2018 | xboxone |
| Turret Tower - The Enemy Has Arrived | 2001 | arcade |
| Turrican Anthology Vol. I | 2022 | ps4, switch |
| Turrican Anthology Vol. II | 2022 | ps4, switch |
| Turrican Flashback | 2020 | ps4, switch |
| Turtle Ship | 1988 | arcade |
| Tut's Tomb | 1996 | arcade |
| Twin Action | 1995 | arcade |
| Twin Bee Yahhoo! | 1995 | arcade |
| Twin Caliber | 2002 | ps2 |
| Twin Cobra | 1990 | nes |
| Twin Cobra | 1987 | arcade |
| Twin Cobra | 1987 | arcade |
| Twin Cobra II | 1995 | arcade |
| Twin Eagle | 1989 | nes |
| Twin Eagle - Revenge Joe's Brother | 1988 | arcade, nes |
| Twin Eagle II - The Rescue Mission | 1994 | arcade |
| Twin Falcons | 1989 | arcade |
| TwinBee | 1985 | arcade, fds, nes |
| TwinBee | | sg1000 |
| TwinBee | 2013 | wiiu |
| Twinkle Star Sprites | 1996 | arcade, dreamcast, neogeo, neogeocd, saturn |
| Twinkle Tale | 1993 | arcade |
| Twisted Metal | 2012 | ps3 |
| Twisted Metal - Head-On - Extra Twisted Edition | 2008 | ps2 |
| Two Ships | 2025 | genesis |
| Two Tigers | 1984 | arcade |
| TxK | 2014 | vita |
| Typhoon | 1987 | arcade |
| Tyrannosaurus Tex | 2018 | gbc |
| Tyrian 2000 | 2007 | gba |
| Tyrian 2000 | 2000 | gbc |
| U.N. Defense Force: Earth Joker | 1993 | arcade |
| U.N. Squadron | 1989 | arcade |
| U.S. Navy | 1990 | arcade |
| UFO | 1981 | o2 |
| UFO Commando | 2010 | xbox360 |
| UFO Invaders | 2023 | nes |
| UFO Robot Attack | 1979 | arcade |
| US AAF Mustang | 1990 | arcade |
| Uchuu Keibitai SDF | 1990 | nes |
| Uchuu no Kishi - Tekkaman Blade | 1993 | snes |
| Ufo Robo Dangar | 1986 | arcade |
| Ultimate Ecology | 1993 | arcade |
| Ultimate Paintball | 2000 | gbc |
| Ultimate Shooting Collection | 2008 | wii |
| Ultra Invaders | 1980 | arcade |
| Ultra Mission | 2021 | vita |
| Ultra X Weapons / Ultra Keibitai | 1995 | arcade |
| Ultracore | 2019 | genesis, vita |
| Ultraman Club - Tatakae! Ultraman Kyoudai!! | 1992 | arcade |
| Ultratron | 2015 | ps3, ps4, vita, wiiu |
| The Uncanny X-Men | 1989 | nes |
| Undead Storm Nightmare | 2015 | 3ds |
| Under Defeat | 2005 | arcade, dreamcast |
| Under Defeat HD | 2012 | ps3, xbox360 |
| Under Defeat HD - Deluxe Edition | 2012 | ps3 |
| Under Defeat HD - Deluxe Edition | | xbox360 |
| Under Fire | 1993 | arcade |
| UnderCover AD2025 Kei | 2000 | dreamcast |
| Underground Mission | | nes |
| Undertow | 2007 | xbox360 |
| Underwater Attack | 2008 | nds |
| Underworld - The Eternal War | 2004 | ps2 |
| Unearthed - Trail of Ibn Battuta | 2013 | ps3 |
| UniWar S | 1980 | arcade |
| Unit 13 | 2012 | vita |
| Unknown Soldier - Mokuba no Houkou | 2008 | nds |
| Unreal Championship | 2002 | xbox |
| Unreal Championship 2 - The Liandri Conflict | 2005 | xbox |
| Unreal II - The Awakening | 2004 | xbox |
| Unreal Tournament | 2000 | dreamcast, ps2 |
| Unreal Tournament III | 2007 | ps3, xbox360 |
| Unreal Tournament III | 2006 | ps3 |
| Untouchable | 1992 | svision |
| The Untouchables | 1991 | nes |
| The Untouchables | 1994 | snes |
| Up Scope | 1986 | arcade |
| Urban Chaos - Riot Response | 2006 | ps2, xbox |
| Urban Strike | 1994 | gb, genesis, gg, snes |
| Urban Strike | 1995 | nes |
| Uridium | 2008 | wii |
| Us vs. Them | 1984 | arcade |
| Uzu Keobukseon | 1992 | genesis |
| V-Five | 1993 | arcade |
| VS. Duck Hunt | 1985 | arcade |
| VS. Freedom Force | 1988 | arcade |
| VS. Gradius | 1986 | arcade |
| VS. Hogan's Alley | 1985 | arcade |
| VS. Platoon | 1987 | arcade |
| VS. Star Luster | 1985 | arcade |
| VS. Top Gun | 1987 | arcade |
| Vaccine | 2017 | wiiu, xboxone |
| Vampire Night | 2001 | arcade, ps2 |
| Vampire Rain - Altered Species | 2008 | ps3 |
| Van Helsing | 2004 | gba, ps2, xbox |
| Vanark | 2000 | ps1 |
| Vanguard | 1981 | arcade |
| Vanguard II | 1984 | arcade |