| Rockman - Power Battle Fighters | 2017 | ps3 |
| Rockman Classics Collection | 2016 | 3ds |
| Rolling Crash / Moon Base | 1979 | arcade |
| Rumble Station - 15 in 1 | | nes |
| SEGA Arcade Gallery | 2003 | gba |
| SEGA Smash Pack | 2002 | gba |
| SNK Arcade Classics Vol. 1 | 2008 | ps2, wii |
| SY-888B 288 in 1 Handheld | 2016 | arcade |
| Sampler Disc for PSP Vol. 1 | 2005 | psp |
| Samurai Shodown II | 2008 | xbox360 |
| Sanguo Lieche | 1999 | arcade |
| SatMag Sono CD | 1998 | saturn |
| Saturn CG Selection Vol. 1 | 1995 | saturn |
| Schnappi - Das kleine Krokodil - 3 Fun-Games | 2005 | ps1 |
| Seawolf / Missile | 1978 | astrocade |
| Sega 3D Fukkoku Archives 2 | 2015 | 3ds |
| Sega Ages - Columns Arcade Collection | 1997 | saturn |
| Sega Ages - Memorial Selection Vol. 1 | 1997 | saturn |
| Sega Ages - Memorial Selection Vol. 2 | 1997 | saturn |
| Sega Ages - Rouka ni Ichidanto R | 1996 | saturn |
| Sega Ages - Shukudai ga Tanto R | 1996 | saturn |
| Sega Ages 2500 Series Vol. 21 - SDI & Quartet - Sega System 16 Collection | 2005 | ps2 |
| Sega Ages Volume 1 | 1997 | saturn |
| Sega Classic Arcade Collection - Limited Edition | 1993 | segacd |
| Sega Classics Arcade Collection - Limited Edition | 1992 | segacd |
| Sega Flash Vol. 1 | 1997 | saturn |
| Sega Flash Vol. 2 | 1996 | saturn |
| Sega Flash Vol. 3 | 1996 | saturn |
| Sega Flash Vol. 4 | 1997 | saturn |
| Sega Flash Vol. 5 | 1997 | saturn |
| Sega Flash Vol. 6 | 1997 | saturn |
| Sega Flash Vol. 7 | 1998 | saturn |
| Sega Genesis Classics | 2018 | ps4, switch, xboxone |
| Sega Genesis Collection | 2006 | ps2, psp |
| Sega Mega Drive Collection | 2006 | ps2, psp |
| Sega Mega Drive Ultimate Collection | 2009 | ps3, xbox360 |
| Sega Saturn Bootleg II - On the Road | 1996 | saturn |
| Sega Saturn Choice Cuts | 1995 | saturn |
| Sega Screams Volume 2 | 1997 | saturn |
| Sega Smash Pack - Volume 1 | 2001 | dreamcast |
| Sega Sports 1 | 1995 | genesis |
| Sega Top Five | 1997 | genesis |
| Sega Vintage Collection - Alex Kidd & Co | 2012 | xbox360 |
| Sega Vintage Collection - Golden Axe | 2012 | xbox360 |
| Sega Vintage Collection - Monster World | 2012 | xbox360 |
| Sega Vintage Collection - Streets of Rage | 2012 | xbox360 |
| Sega Vintage Collection - ToeJam & Earl | 2012 | xbox360 |
| Sengoku Musou 2 with Moushouden & Empires HD Version | 2013 | ps3 |
| Serial Players Only | 1996 | ps1 |
| The Serious Sam Collection | 2013 | xbox360 |
| Short Order + Eggsplode! | 1989 | nes |
| Short Warp - Warp's Short Game Collection | 1996 | 3do |
| Silent Scope Complete | 2004 | xbox |
| Simple 2960 Tomodachi Series Vol. 4 - The Trump - Minna de Asoberu 12 Shurui no Trump Game | 2003 | gba |
| Simple DS Series Vol. 30 - The Table Game - Mahjong, Igo, Shougi, Card, Hanafuda, Reversi, Gomoku Narabe | 2007 | nds |
| Simple DS Series Vol. 5 - The Trump | 2006 | nds |
| The Simpsons Arcade Game | 2012 | ps3, xbox360 |
| Sleepwalker & Pinball Fantasies | 1993 | cd32 |
| Smash TV | 2005 | xbox360 |
| Solitaire Overload | 2007 | nds |
| Sonic Compilation | 1995 | genesis |
| Sonic The Hedgehog 3 | 2009 | xbox360 |
| Sonic's Ultimate Genesis Collection | 2009 | ps3, xbox360 |
| Space Attack / Head On | 1979 | arcade |
| Space Invaders - Virtual Collection | 1995 | vb |
| Space Invaders / Qix Silver Anniversary Edition | 2003 | arcade |
| Space Invaders Multigame | 2002 | arcade |
| Space Invasion & Karate Joe | 2001 | gbc |
| Space Invasion & Painter | 2001 | gbc |
| Speed Math / Bingo Math | 1978 | astrocade |
| Speedball 2 - Brutal Deluxe | 2007 | xbox360 |
| Sport Games | 1998 | genesis |
| Sports Collection | 1996 | gb |
| Sportsmans Pack 2 in 1 - Cabela's Big Game Hunter + Rapala Pro Fishing | 2004 | gba |
| Spyro Superpack - Spyro - Season of Ice + Spyro 2 - Season of Flame | 2001 | gba |
| Square Maniacs '98 | 1998 | ps1 |
| Station 2 | 1998 | ps1 |
| Station 3 | 1998 | ps1 |
| Station 8 | 1999 | ps1 |
| Street Fighter II - Hyper Fighting | 2006 | xbox360 |
| Street Fighter III - Double Impact | 2000 | dreamcast |
| Street Fighter III - W Impact | 1999 | dreamcast |
| Street Games | 1993 | arcade |
| Street Games II | 1993 | arcade |
| Streets of Rage 2 | 2007 | xbox360 |
| Sunday Funday - The Ride | 1995 | nes |
| Sunset Riders / Super Street Fighter II - The New Challengers | 1994 | arcade |
| Super 20 Hab | | snes |
| Super ABC | 1999 | arcade |
| Super Arcade 101-in-1 | | arcade |
| Super Asteroids, Missile Command | 1995 | lynx |
| Super Bomberman Collection | 2026 | switch |
| Super CD-ROM^2 Taiken Soft Shuu | 1991 | pcengine |
| Super Cartridge Ver 1 - 4 in 1 | 1994 | nes |
| Super Cartridge Ver 2 - 10 in 1 | 1994 | nes |
| Super Cartridge Ver 3 - 8 in 1 | 1994 | nes |
| Super Cartridge Ver 4 - 6 in 1 | 1994 | nes |
| Super Cartridge Ver 5 - 7 in 1 | 1994 | nes |
| Super Cartridge Ver 6 - 6 in 1 | 1994 | nes |
| Super Cartridge Ver 7 - 4 in 1 | 1994 | nes |