| Ugetsu Kitan | 1996 | ps1 |
| The Ultimate Noah's Ark | 1994 | cdi |
| Umineko When They Cry | 2021 | ps4 |
| Umineko no Naku Koro ni Chiru - Shinjitsu to Gensou no Yasoukyoku | 2011 | ps3 |
| Umineko no Naku Koro ni Portable 1 | 2011 | psp |
| Umineko no Naku Koro ni Portable 2 | 2011 | psp |
| Umishou | 2007 | ps2 |
| Un:Logical | 2026 | switch |
| Unavowed | 2021 | switch |
| The Uncertain: Last Quiet Day | 2022 | ps4, switch |
| The Uncertain: Light at the End | | ps4 |
| Uncharted Tides: Port Royal | 2020 | ps4 |
| Uncharted Waters | 1991 | genesis, nes, snes |
| Undead Knights | 2009 | psp |
| Under the Moon - Crescent | 2009 | ps2 |
| Undercover - Dual Motives | 2004 | nds |
| Underground | 2015 | wiiu |
| Unfabulous | 2006 | gba |
| Unforeseen Incidents | 2022 | switch |
| Uniform girlfriend 2 | 2025 | ps4 |
| Uninvited | 1989 | nes |
| Universal Nuts | 1997 | ps1, saturn |
| Universe | 1994 | cd32 |
| Unknown Variable 2 - Raven's Ridge | 1997 | ps1 |
| Unreal Life | 2020 | switch |
| The Unsolved | 1997 | saturn |
| The Unsolved - Hyper Science Adventure | 1997 | ps1 |
| Unsolved Crimes | 2008 | nds |
| Up | 2009 | psp |
| Up | 2009 | psp |
| Uragiri wa Boku no Namae o Shitteiru - Tasogare ni Ochita Inori | 2010 | ps2 |
| Urakata Hakuouki | 2013 | psp |
| Urakata Hakuouki - Akatsuki no Shirabe | 2014 | psp |
| Urban Myth Dissolution Center | 2025 | switch |
| Urban Yeti! | 2002 | gba |
| Urusei Yatsura - Dear My Friends | 1994 | segacd |
| Urusei Yatsura - Endless Summer | 2005 | nds |
| Urusei Yatsura - Stay with You | 1990 | pcengine |
| Usotsuki Shangri-La | 2017 | vita |
| Uta no Prince-sama | 2010 | psp |
| Uta no Prince-sama - All Star | 2013 | psp |
| Uta no Prince-sama - All Star After Secret | 2015 | psp |
| Uta no Prince-sama - Amazing Aria | 2010 | psp |
| Uta no Prince-sama - Music | 2011 | psp |
| Uta no Prince-sama - Repeat | 2011 | psp |
| Uta no Prince-sama - Sweet Serenade | 2011 | psp |
| Utakata no Uchronia: Trail | 2025 | switch |
| Utau - Tumbling Dice | 2004 | dreamcast |
| Utawarerumono - Chiri Yuku Mono e no Komoriuta | 2006 | ps2 |
| Utawarerumono - Itsuwari no Kamen | 2015 | vita |
| Utawarerumono: Mask of Deception | 2015 | ps4 |
| Utawarerumono: Mask of Truth | 2016 | ps4, vita |
| Utsusemi no Meguri | 2017 | vita |
| Uwasa no Midori-kun!! - Natsuiro Striker | 2007 | nds |
| Uwasa no Midori-kun!! 2 - Futari no Midori! | 2008 | nds |
| Uzumaki - Denshi Kaiki Hen | 2000 | ws |
| Uzumaki - Noroi Simulation | 2000 | ws |
| VA-11 Hall-A | 2017 | vita |
| VA-11 Hall-A: Cyberpunk Bartender Action | 2019 | ps4, switch |
| VIP News | 2004 | nds |
| Vacation Adventures - Park Ranger | 2014 | 3ds |
| Valhalla Hills: Definitive Edition | 2017 | ps4 |
| ValiDate: Struggling Singles in Your Area | 2022 | switch |
| Valiant Hearts - The Great War | 2014 | ps3, ps4, switch, xbox360, xboxone |
| Valkyrie no Densetsu | 1989 | arcade, pcengine |
| Vambrace: Cold Soul | 2019 | ps4, switch, xboxone |
| Vampire Knight DS | 2009 | nds |
| Vampire Night Shift | 2020 | gb |
| Vampire: The Masquerade – Coteries of New York | 2020 | ps4, switch, xboxone |
| Vampire: The Masquerade – Shadows of New York | 2020 | ps4, switch |
| Vamwolf Cross | 2015 | vita |
| Vane | 2019 | ps4 |
| Variable Barricade | 2018 | vita |
| Vasilis | 2020 | vita, xboxone |
| Vay | 1994 | segacd |
| Vecinos Invasores | 2006 | gba |
| VeggieTales - LarryBoy and the Bad Apple | 2006 | gba |
| Vera Blanc: Full Moon | 2020 | ps4, switch, xboxone |
| Verrat in der Verbotenen Stadt | 1999 | ps1 |
| Versailles - A Game of Intrigue | 1998 | ps1 |
| Versalles - Complot en la Corte del Rey Sol | 1999 | ps1 |
| Vesta | 2018 | xboxone |
| Viking Child | 1991 | lynx |
| Virche Evermore: Epic Lycoris | 2023 | switch |
| Virginia | 2016 | ps4, xboxone |
| Virtual Sex | | ps1 |
| Virtual Ties Isekaijoucho Träumerei | 2026 | ps4, switch |
| Virtual Vivid | 1994 | 3do |
| Virus | 1997 | saturn |
| Vitamin X Destination | 2018 | vita |
| VitaminX - We are Super Supriment Boys | 2007 | ps2 |
| VitaminX Detective B6 | 2012 | psp |
| VitaminX Evolution Plus | 2010 | psp |
| VitaminXtoZ | 2011 | psp |
| VitaminZ - Welcome Our New Supplement Boys | 2009 | ps2 |
| VitaminZ Revolution | 2010 | psp |
| Vividred Operation - Hyper Intimate Power | 2013 | ps3 |
| Voice Paradice Excella | 1996 | ps1 |
| Voyeur | 1993 | cdi |
| Voyeur ...Don't Get Caught | 1993 | cdi |