| Nightruth - Explanation of the Paranormal 01 - Yami no Tobira | 1996 | saturn |
| Nijuuei | 2002 | dreamcast |
| Nil Admirari no Tenbin - Teito Genwaku Kitan | 2016 | vita |
| NinNinDays | 2020 | switch |
| Nine Hours, Nine Persons, Nine Doors | 2009 | nds |
| Ninja Boy | 1990 | gb |
| Ninja Boy 2 | 1993 | gb |
| Ninja Gaiden Trilogy | 1995 | snes |
| Ninja JaJaMaru - The Ninja Skill Book | | nes |
| Ninja Jajamaru - Ginga Daisakusen | 1991 | nes |
| Ninja Katsugeki - Tenchu - Kurenai Portable | 2010 | psp |
| Ninja Katsugeki - Tenchu San Portable | 2009 | psp |
| Ninja Ryuuken Den Tomoe | 1995 | snes |
| Ninja Teenz - The Revival | 2022 | nes |
| Nise no Chigiri - Omoide no Saki e | 2011 | psp |
| Nishimura Kyotaro Travel Mystery - Akugyaku no Kisetsu - Tokyo Nanki-Shirahama Renzoku Satsujin Jiken | 2009 | psp |
| Nishimura Kyoutarou Mystery - Blue Train Satsujin Jiken | 1989 | nes |
| Nishimura Kyoutarou Mystery - Hokutosei no Onna | 1990 | pcengine |
| Nishimura Kyoutarou Mystery - Super Express Satsujin Jiken | 1990 | nes |
| Nishimura Kyoutarou Travel Mystery - Akugyaku no Kisetsu - Tokyo ~ Nanki-Shirahama Renzoku Satsujin Jiken | 1994 | 3do |
| No Case Should Remain Unsolved | 2024 | switch |
| No Fate! Only the Power of Will | 2010 | psp, xbox360 |
| No Good Choice | 2020 | nes |
| No Longer Home | 2021 | switch |
| No Sleep for Kaname Date – From AI: The Somnium Files | 2026 | ps4 |
| No-Ri-Ko | 1988 | pcengine |
| No-appointment Gals Olympos | 1996 | saturn |
| Nobunaga Hiroku - Geten no Yume | 1997 | ps1 |
| Nobunaga Shippuuki - Kirameki | 1996 | ps1 |
| Noddy - Una Aventura Magica | 2001 | ps1 |
| Noddy and the Magic Book | 2006 | ps2 |
| Noddy's Magic Adventure | 2000 | ps1 |
| Noel - La Neige | 1998 | ps1 |
| Noel - La Neige Special | 1998 | ps1 |
| Noel - Not Digital | 1996 | ps1 |
| Noel 3 - Mission on the Line | 1999 | ps1 |
| Noel 3 - Not Digital | 1998 | saturn |
| Noel The Mortal Fate | 2022 | ps4, switch |
| Nogizaka Haruka no Himitsu - Cosplay, Hajimemashita | 2008 | ps2 |
| Noir Chronicles: City of Crime | 2018 | ps4 |
| Noir Chronicles: City of Crime | 2018 | xboxone |
| Non Casual Encounter - Prologue | 2021 | dreamcast |
| Nonomura Byouin no Hitobito | 1996 | saturn |
| Nora to Oujo to Noraneko Heart 2 | 2019 | vita |
| A Normal Lost Phone | 2018 | switch |
| Norn9 - Last Era | 2015 | vita |
| Norn9 - Var Commons | 2014 | vita |
| North | 2018 | vita, xboxone |
| North Wind - Eien no Yakusoku | 2005 | ps2 |
| Nos Voisins, les Hommes | 2006 | gba |
| Nostalgia 1907 - In North Atlantic Sea | 1991 | segacd |
| Nostos | 2020 | ps4 |
| Nukumori no Naka de - In the Warmth | 2001 | ps1 |
| Nurse Love Addiction | 2017 | switch, vita |
| Nurse Love Syndrome | 2019 | switch |
| Nurse Love Syndrome | 2019 | vita |
| Nurse Story | 1999 | ps1 |
| Nurse Witch Komugi-chan - Maji-Karte | 2004 | ps2 |
| O.G.A Onigokko Royal - Hunter wa Field de Koi o Suru | 2013 | psp |
| OPUS: Prism Peak | 2026 | switch |
| OPUS: Rocket of Whispers | 2018 | switch |
| OPUS: The Day We Found Earth | 2017 | switch |
| Obduction | 2017 | ps4, xboxone |
| Oblachno, vozmozhny osadki v vide frikadelek | 2009 | psp |
| Observation | 2019 | ps4 |
| Observation | 2020 | xboxone |
| Occultic;Nine | 2017 | ps4, vita, xboxone |
| Oceanhorn: Monster of Uncharted Seas | 2016 | ps4, switch, vita, xboxone |
| Oddworld - Abe's Exoddus | 1999 | ps1 |
| Oddworld - Abe's Oddysee | 1997 | ps1 |
| Oddworld - L'Exode d'Abe | 1999 | ps1 |
| Oddworld - L'Odyssee d'Abe | 1997 | ps1 |
| Odoru Daisousa-sen - The Game - Sensuikan ni Sennyuu Seyo! | 2010 | nds |
| The Office Quest | 2020 | ps4, xboxone |
| Ohenro-San - Hosshin no Dojo Hen | 2003 | gc |
| Oishinbo - Kyuukyoku no Menu Sanbon Shoubu | 1989 | nes |
| Oita Beppu Mystery Guide: The Warped Bamboo Lantern | 2022 | ps4 |
| Ojousama Express | 1998 | ps1 |
| Ojousama Express | 1998 | saturn |
| Ojousama Kumikyoku - Sweet Concert | 2007 | ps2 |
| Ojousama Sousamou | 1996 | pcfx |
| Ojousama o Nerae!! | 1998 | saturn |
| Okashi na Shima no Peter Pan - Sweet Never Land | 2011 | psp |
| Old Man's Journey | 2018 | ps4, switch, xboxone |
| Olympia Soirée: Catharsis | | switch |
| Olympus no Tatakai | 1988 | nes |
| Omensight: Definitive Edition | 2018 | switch |
| Omerta - Chinmoku no Okite - The Legacy | 2014 | psp |
| Omerta Code - Tycoon Kai | 2016 | vita |
| Omochabako no Kuni no Alice - Wonderful Wonder World | 2011 | psp |
| Omoi no Kakera - Close to | 2006 | ps2 |
| Omoi no Kakera - Close to | 2011 | psp |
| Omoide ni Kawaru Kimi - Memories Off | 2002 | dreamcast, ps2 |
| Omoide ni Kawaru Kimi - Memories Off | 2008 | psp |
| Omoikkiri Tanteidan HaadoGumi - Matenrou no Chousenjou | 1988 | fds |
| On the Rain-Slick - Precipice of Darkness - Episode One | 2008 | ps3 |
| On the Rain-Slick - Precipice of Darkness - Episode Two | 2008 | ps3 |
| Once Upon a Time | 2010 | wii |
| One Eyed Kutkh | 2018 | vita, xboxone |
| One Night Stand | 2019 | ps4, switch, xboxone |