| Uncle Fester's Quest: The Addams Family | 1989 | arcade |
| Uncle Poo | 1983 | arcade |
| Undead Line | 1991 | genesis |
| Undercover Cops | 1995 | snes |
| Undercover Shot | 2025 | nes |
| Undersea Treasure Hunting | 2025 | genesis |
| Undou Busoku Kaishou! Punch de Diet | 2002 | ps1 |
| The Unholy War | 1998 | ps1 |
| Universal Chaos | 1989 | a2600 |
| The Universe Soldiers | 1993 | nes |
| Unstoppable Knight | 2021 | genesis |
| Until You Fall | 2020 | ps4 |
| Uo - 7-tsu no Mizu to Densetsu no Nushi | 2004 | ps2 |
| Uoozu | 1990 | gb |
| Up'n Down | 1983 | arcade |
| Uprising X | 1998 | ps1 |
| Urachacha Mudaeri | 2002 | arcade |
| Urban Chaos | 2000 | dreamcast, ps1 |
| Urban Constructor | 2005 | ps2 |
| Urban Reign | 2005 | ps2 |
| Urban Trial Playground | 2018 | switch |
| Uta no Prince-sama - Debut | 2012 | psp |
| Uta no Prince-sama - Music 2 | 2013 | psp |
| Utaco | 2015 | nes |
| Utawarerumono: Zan | 2018 | ps4 |
| V-V | 1994 | genesis |
| V.I.P | 2001 | gba, ps1, ps2 |
| V2000 | 1998 | ps1 |
| VRog | 2016 | wiiu |
| VS Battler | 1990 | gb |
| VS Block Breaker | 1997 | arcade |
| VS. Battle City | 1985 | arcade |
| VS. Clu Clu Land | 1984 | arcade |
| VS. Pinball | 1984 | arcade |
| Vagrant Story | 2000 | ps1 |
| Valis: The Fantasm Soldier Collection | 2021 | switch |
| Valkyria Revolution | 2017 | xboxone |
| Valkyrie no Bouken - Toki no Kagi Densetsu | 1986 | nes |
| Vampir - Kyuuketsuki Densetsu | 1999 | ps1 |
| Vampire | 1983 | arcade |
| Vampire Hunter D | 1999 | ps1 |
| Vampire Panic | 2004 | ps2 |
| Van-Van Car | 1983 | arcade |
| Vanguard | 1982 | a2600, a5200 |
| Vapor Trail | 1991 | genesis |
| Vault Assault | 2001 | a2600 |
| Vectorman | 1995 | genesis, wii |
| Vectorman 2 | 1996 | genesis |
| Vectron | 1982 | intv |
| Veggie Invasion | 2020 | nes |
| Vehicle Cavalier | 1996 | ps1 |
| Velious - Roland no Majuu | 1990 | gb |
| Velldeselba Senki - Tsubasa no Kunshou | 1997 | ps1 |
| Velocibox | 2015 | vita |
| Velvet File Plus | 2001 | ps2 |
| Venture | 1981 | a2600, arcade, col, intv |
| Verlet Swing | 2019 | xboxone |
| Verytex | 1991 | genesis |
| Vessel | 2014 | ps3 |
| Vib-Ripple | 2004 | ps2 |
| Victory | 1983 | col |
| Victory Run | 1987 | pcengine, wiiu |
| Video Jogger | 1984 | a2600 |
| Video Olympics ~ Pong Sports | 1977 | a2600 |
| Video Pinball | 1979 | a2600, arcade |
| Video Pinball ~ Arcade Pinball | 1981 | a2600 |
| Video Reflex | 1984 | a2600 |
| The VideoKid | 2018 | xboxone |
| Vigilante | 1989 | pcengine |
| Vigilante | 1989 | sms |
| Vigilante | 2007 | wii |
| Vigilante 8 | 1998 | n64, ps1 |
| Vigilante 8 - 2nd Battle | 2000 | dreamcast, ps1 |
| Vigilante Ninja II | 2017 | nes |
| Viral Survival | 2010 | wii |
| Virtua Fighter 2 | 1996 | genesis |
| Virus - It Is Aware | 1999 | ps1 |
| Virus Singularity | 2025 | genesis |
| Vital Light | 1994 | cd32 |
| Vogel Flieh | 1983 | a2600 |
| Volfied | 1991 | genesis |
| Volly | 1973 | arcade |
| Vroom in the Night Sky | 2017 | switch |
| Vulcanus | 2006 | psp |
| WTA Tour Tennis Pocket | 2002 | gba |
| WWII - Battle over Europe | 2007 | ps2 |
| WWII - Tank Battles | 2006 | ps2 |
| Wabbit | 1982 | a2600 |
| Wagamama Fairy Mirumo de Pon! - Nazo no Kagi to Shinjitsu no Tobira | 2004 | gba |
| Wagyan Paradise | 1994 | snes |
| Waiwai Animal Land Jr | 1993 | arcade |
| Waku Puyo Dungeon - Ketteiban | 1999 | ps1 |
| Wall Ball | 1983 | a2600 |
| Wall Crash | 1984 | arcade |
| Wall Street | 1982 | arcade |
| Wall-Defender | 1984 | a2600 |
| Wallace & Gromit in Project Zoo | 2003 | gc, ps2, xbox |
| Walt Disney Pictures Presents Meet the Robinsons | 2007 | gc, ps2 |
| Wander and the Colossus | 2005 | ps2 |
| Wander to Kyozou | 2005 | ps2 |